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You Searched For: NF-\\\\u03BAB+Activation+Inhibitor+III


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Product Image-76293-016

NF-κB Activation Inhibitor III ≥99%

Supplier: Cayman Chemical Company
Description: NF-KB Activation Inhibitor III, Purity >/=99%, CAS 380623-76-7, MF: C10H5ClN4O5S, MW: 328.7, Synonyms: SM-7368, 3-chloro-4-nitro-N-(5-nitro-2-thiazolyl)-benzamide, Formulation: A crystalline solid, Storage: -20C, Size: 5mg

Product Image-10068-698

Anti-CHUK Rabbit Polyclonal Antibody

Catalog Number: (10068-698)
Supplier: Prosci
Description: Acts as part of the IKK complex in the conventional pathway of NF-κ-B activation and phosphorylates inhibitors of NF-κ-B thus leading to the dissociation of the inhibitor/NF-κ-B complex and ultimately the degradation of the inhibitor. As part of the non-canonical pathway of NF-κ-B activation, the MAP3K14-activated CHUK/IKKA homodimer phosphorylates NFKB2/p100 associated with RelB, inducing its proteolytic processing to NFKB2/p52 and the formation of NF-κ-B RelB-p52 complexes. Also phosphorylates NCOA3. Phosphorylates 'Ser-10' of histone H3 at NF-κ-B-regulated promoters during inflammatory responses triggered by cytokines.
Image Unavailable-77439-660

Anti-IKK Gamma Rabbit Polyclonal Antibody

Catalog Number: (77439-660)
Supplier: Bioss
Description: Regulatory subunit of the IKK core complex which phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Also considered to be a mediator for TAX activation of NF-kappa-B. Could be implicated in NF-kappa-B-mediated protection from cytokine toxicity (By similarity). Essential for viral activation of IRF3.

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Product Image-10813-826

Anti-CHUK Rabbit Polyclonal Antibody

Catalog Number: (10813-826)
Supplier: Prosci
Description: Acts as part of the IKK complex in the conventional pathway of NF-kappa-B activation and phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. As part of the non-canonical pathway of NF-kappa-B activation, the MAP3K14-activated CHUK/IKKA homodimer phosphorylates NFKB2/p100 associated with RelB, inducing its proteolytic processing to NFKB2/p52 and the formation of NF-kappa-B RelB-p52 complexes. Also phosphorylates NCOA3.
Image Unavailable-102979-958

Anti-Nuclear Factor NF-kappaB Essential Modulator;NEMO;IKKG;FIP-3 Rabbit Polyclonal Antibody

Catalog Number: (102979-958)
Supplier: Adipogen
Description: IKK-gamma is the regulatory subunit of the IKK core complex which phosphorylates inhibitors of NF-kappaB, thus leading to the dissociation of the inhibitor/NF-kappaB complex and ultimately the degradation of the inhibitor. Its binding to scaffolding polyubiquitin seems to play a role in IKK activation by multiple signaling receptor pathways. IKK-gamma is also considered to be a mediator for TAX activation of NF-kappaB and it could be implicated in NF-kappaB-mediated protection from cytokine toxicity. It is essential for viral activation of IRF3 and is involved in TLR3- and IFIH1-mediated antiviral innate response.
Product Image-76293-022

NF-κB Inhibitor (SN50)

Supplier: Cayman Chemical Company
Description: A synthetic peptide corresponding to the nuclear localization sequence of NF-κB p105 subunit (also known as p50) appended to a hydrophobic sequence to facilitate import into living cells; blocks the nuclear import of p105 in cells treated with activators of NF-κB signaling, including LPS and TNF-α.

Image Unavailable-102516-104

CHS-828 ≥98%

Supplier: Adipogen
Description: Antitumor compound. Programmed cell death inducer. Cytotoxic. Antiproliferative. p53 activator. IkappaB kinase inhibitor. NF-kappaB inhibitor. Nampt/visfatin inhibitor.

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Product Image-10068-838

Anti-CHUK Rabbit Polyclonal Antibody

Catalog Number: (10068-838)
Supplier: Prosci
Description: Acts as part of the IKK complex in the conventional pathway of NF-κ-B activation and phosphorylates inhibitors of NF-κ-B thus leading to the dissociation of the inhibitor/NF-κ-B complex and ultimately the degradation of the inhibitor. As part of the non-canonical pathway of NF-κ-B activation, the MAP3K14-activated CHUK/IKKA homodimer phosphorylates NFKB2/p100 associated with RelB, inducing its proteolytic processing to NFKB2/p52 and the formation of NF-κ-B RelB-p52 complexes. Also phosphorylates NCOA3. Phosphorylates 'Ser-10' of histone H3 at NF-κ-B-regulated promoters during inflammatory responses triggered by cytokines.
Product Image-89146-810

Protease Inhibitor I aldehyde

Supplier: Enzo Life Sciences
Description: Cell permeable inhibitor of the 26S proteasome (MCP; multicatalytic proteinase complex) in HT4 cells. Causes accumulation of ubiquitinylated proteins in neuronal cells. Prevents the activation of NF-κB in response to TNF-α or okadaic acid through inhibition of IκBα degradation.

Image Unavailable-103008-418

NF-kB Inhibitor

Catalog Number: (103008-418)
Supplier: Anaspec Inc
Description: SN50 is a NF-κB cell-permeable inhibitory peptide. it consists of the hydrophobic region of the signal peptide of Kaposi fibroblast growth factor (K-FGF) attached to a NF-kB p50 nuclear localization sequence (NLS). SN50 inhibits translocation of the NF-kB active complex into the nucleus.
Sequence:AAVALLPAVLLALLAPVQRKRQKLMP
MW:2781.5 Da
% peak area by HPLC:95
Storage condition:-20° C
Image Unavailable-89149-082

Panepoxydone (from Lentinus crinitus) ≥95% (by HPLC, MS)

Catalog Number: (89149-082)
Supplier: Enzo Life Sciences
Description: Antibiotic. Inhibitor of NF-κB activation by preventing the phosphorylation of IκB protein and thereby interrupts the signalling pathway. Strongly inhibits the expression of several NF-κB dependent pro-inflammatory genes.
Image Unavailable-76293-012

JSH-23 ≥98%

Supplier: Cayman Chemical Company
Description: JSH-23, Purity >/=98%, CAS 749886-87-1, MF: C16H20N2, MW: 240.3, Synonyms: NF-KB Activation Inhibitor II, 4-methyl-N1-(3-phenylpropyl)-1,2-benzenediamine, Formulation: A crystalline solid, Storage: -20C, Size: 5mg

Product Image-10069-028

Anti-IKBKB Rabbit Polyclonal Antibody

Catalog Number: (10069-028)
Supplier: Prosci
Description: Acts as part of the IKK complex in the conventional pathway of NF-κ-B activation and phosphorylates inhibitors of NF-κ-B thus leading to the dissociation of the inhibitor/NF-κ-B complex and ultimately the degradation of the inhibitor. Also phosphorylates NCOA3.
Product Image-10354-634

Anti-IKBKG Rabbit Polyclonal Antibody

Catalog Number: (10354-634)
Supplier: Bioss
Description: Regulatory subunit of the IKK core complex which phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Its binding to scaffolding polyubiquitin seems to play a role in IKK activation by multiple signaling receptor pathways. However, the specific type of polyubiquitin recognized upon cell stimulation (either 'Lys-63'-linked or linear polyubiquitin) and its functional importance is reported conflictingly. Also considered to be a mediator for TAX activation of NF-kappa-B. Could be implicated in NF-kappa-B-mediated protection from cytokine toxicity. Essential for viral activation of IRF3. Involved in TLR3- and IFIH1-mediated antiviral innate response; this function requires 'Lys-27'-linked polyubiquitination.
Image Unavailable-10432-830

Anti-TRAF3IP2 Rabbit Polyclonal Antibody

Catalog Number: (10432-830)
Supplier: Bioss
Description: Could be involved in the activation of both NF-kappa-B via a NF-kappa-B inhibitor kinase (IKK)-dependent mechanism and stress-activated protein kinase (SAPK)/JNK.
Image Unavailable-102515-828

Avarol ≥97% (by HPLC)

Catalog Number: (102515-828)
Supplier: Adipogen
Description: Antibacterial against selected Gram-positive strains, antifungal. Anticancer compound. Antileukemic. Antimitotic agent. Antiviral compound. Inhibits HIV activity. Anti-inflammatory. Synovial phospholipase A2, cyclooxygenase and lipoxygenase inhibitor. Modulator of superoxide dismutase and glutathione peroxidase. Platelet aggregation inhibitor. Anti-psoriatic, mediated by inhibition of TNF-alpha generation and NF-kappaB activation. Reviews.

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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