You Searched For: N-(1,1,3,3-Tetramethylbutyl)acrylamide

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Anti-CLASP1 Mouse Monoclonal Antibody [clone: 6A11]

Catalog Number: (103341-208)

Supplier: Novus Biologicals

Description: The CLASP1 Antibody (6A11) from Novus Biologicals is a mouse monoclonal antibody to CLASP1. This antibody reacts with human. The CLASP1 Antibody (6A11) has been validated for the following applications: Western Blot, ELISA.

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VCV Vertical Electrophoresis Gel System, IBI Scientific

Catalog Number: (14213-244)

Supplier: IBI Scientific

Description: IBI's Variable Comb Vertical (VCV) System is designed for high resolution and rapid analysis of protein and nucleic acid samples in 18x22cm format agarose and polyacrylamide gels

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Bisacrylamide ≥99%

Supplier: BeanTown Chemical

Description: CAS: 110-26-9; EC No: 203-750-9; MDL No: MFCD00008625; RTECS: AS3678000 Powder; Linear Formula: (H2C=CHCONH)2CH2; Molecular Formula: C7H10N2O2; MW: 154.17 Melting Point: <gt/>300° Density (g/mL): 1.235 Air Sensitive, Light Sensitive

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Bisacrylamide ≥97%

Supplier: BeanTown Chemical

Description: CAS: 110-26-9; EC No: 203-750-9; MDL No: MFCD00008625; RTECS: AS3678000 Solid; Linear Formula: (CH2=CHCONH)2CH2; Molecular Formula: C7H10N2O2; MW: 154.17 Melting Point: <gt/>300° Density (g/mL): 1.235 Air Sensitive, Light Sensitive

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AV-412 ≥95%

Supplier: Adipogen

Description: AV-412 is a potent dual inhibitor of EGFR and ErbB2 tyrosine kinases, including the mutant EGFR(L858R,T790M), which is clinically resistant to the EGFR-specific kinase inhibitors erlotinib and gefitinib. In enzyme assays assay the compound inhibited the EGFR variants and ErbB2 in the nanomolar range with over 100-fold selectivity compared with other kinases, apart from ABL and FLT1, which were both moderately sensitive to the compound. In cells, AV-412 inhibited autophosphorylation of EGFR and ErbB2 with IC(50) of 43 and 282 nM, respectively. It also inhibited epidermal growth factor (EGF)-dependent cell proliferation with an IC(50) of 100nM. Moreover, AV-412 abrogated EGFR signaling in the gefitinib-resistant H1975 cell line, which harbors a double mutation of L858R and T790M in EGFR. In animal studies using cancer xenograft models, AV-412 (30mg/kg) demonstrated complete inhibition of tumor growth of the A431 and BT-474 cell lines, which overexpress EGFR and ErbB2, respectively.

Agarose, white powder for electrophoresis

Supplier: MP Biomedicals

Description: Agarose is a purified linear galactan hydrocolloid isolated from agar or agar-bearing marine algae.
Agarose is useful in separation of nucleic acids electrophoretically because agarose gels have larger pore sizes than cross linked acrylamide gels at low concentrations and in chromatographic separations by either beading the agarose or cross-linking it. Agarose gels are also used in immunoelectrophoresis (IEP) and double-diffusion Ouchterlony plates to demonstrate antibody-antigen reactions. Agarose was used to prepare 0.5% agarose gel for Southern blot analysis of the DNA extracted from primate muscles.
The following is a list of properties associated with our agaroses: Sulfate content - used as an indicator of purity, since sulfate is the major ionic group present. Gel strength - the force that must be applied to a gel to cause it to fracture. Gel point - the temperature at which an aqueous agarose solution forms a gel as it cools. Agarose solutions exhibit hysteresis in the liquid-to-gel transition - that is, their gel point is not the same as their melting temperature. Electroendosmosis (EEO) - a movement of liquid through the gel. Anionic groups in an agarose gel are affixed to the matrix and cannot move, but dissociable counter cations can migrate toward the cathode in the matrix, giving rise to EEO. Since electrophoretic movement of biopolymers is usually toward the anode, EEO can disrupt separations because of internal convection.

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