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Supplier: Adipogen
Description: Most commonly-used phorbol ester. Binds to and activates protein kinase C (PKC) at nM concentrations. Induces cell growth arrest through a variety of pathways including the mitogen-activated protein kinases (MAPKs), p38 and c-Jun N-terminal kinase (JNK) pathways mediated by cyclin dependent kinase (CDK) inhibitors such as p21WAF1/CIP1, p27KIP1, p15 and p16. Potent mouse skin tumor promoter. Promoter of inducible NOS (iNOS; NOS II). Apoptosis inducer. Potential effective cancer therapeutic agent. Inhibitor of anti-lipolytic activity of insulin.

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Catalog Number: (77977-520)
Supplier: LGC Standards
Description: TRC 1-Amino-2-methylindoline

New Product


Catalog Number: (89367-202)
Supplier: Genetex
Description: Recently a BH3 only member of the Bcl2 family has been identified in human and mouse and designated as Noxa (for damage). The expression of the Noxa gene involves direct activation of its promoter by p53. Increased expression of Noxa protein occurs in normal thymocytes but not in p53 deficient thymocytes. Noxa cDNA codes for a 103 amino acid protein. The co-immunoprecipitation data suggest that Noxa protein may interact with proteins belonging to the Bcl2 family, such as, BclXL and Mcl1. It has also been shown that blocking the endogenous Noxa induction results in the suppression of apoptosis. Treatment of cells with Noxa antisense oligonucleotides blocks radiation induced apoptosis suggesting that Noxa may represent a mediator of p53 dependent apoptosis.


Catalog Number: (RK35012)
Supplier: Restek
Description: Contains: Chain, Compound (CAS#), % by Weight; C8:00 Methyl caprylate (111-11-5), 20%; C10:00 Methyl caprate (110-42-9), 20%; C12:00 Methyl laurate (111-82-0), 20%; C14:00 Methyl myristate (124-10-7), 20%; C16:00 Methyl palmitate (112-39-0), 20%


Catalog Number: (RK35017)
Supplier: Restek
Description: Contains: Chain, Compound (CAS#), % by Weight; C11:00 Methyl undecanoate (1731-86-8), 20%; C12:00 Methyl laurate (111-82-0), 20%; C13:00 Methyl tridecanoate (1731-88-0), 20%; C14:00 Methyl myristate (124-10-7), 20%; C15:00 Methyl pentadecanoate (7132-64-1), 20%


Supplier: Promocell
Description: The PromoCell Melanocyte Growth Medium is a serum-free, PMA (Phorbol Myristate Acetate) containing medium optimized for the cultivation of human melanocytes

Catalog Number: (10208-548)
Supplier: Tonbo Biosciences
Description: Cell stimulation cocktail is a ready to use cocktail that can be used for polyclonal cell activation. It is composed of the phorbol ester, PMA (Phorbol 12-Myristate 13-Acetate), a calcium ionophore (Ionomycin), and the protein transport inhibitors Brefeldin A and Monensin. It can be used to elicit cytokine production and retention in a variety of cell types allowing for detection of intracellular protein by flow cytometry.


Catalog Number: (77440-410)
Supplier: Bioss
Description: eNOS is a calcium/calmodulin dependent enzyme which undergoes several post translational modifications, including acylation with myristate and palmitate, and phosphorylation on numerous residues. As with the other members of the NOS family, eNOS derives the diffusible multifunctional second messenger NO from L arginine through a series of reactions in which L citrulline is an intermediate. eNOS plays an important role in controlling vascular tone, platelet aggregation, and cardiac myocyte function.


Catalog Number: (77977-392)
Supplier: LGC Standards
Description: TRC (Z)-2-(2-Aminothiazol-4-yl)-2-(hydroxyimino)-N-{[(2RS,5RS)-5-methyl-7-oxo-2,4,5,7-tetrahydro-1H-furo[3,4-d][1,3]thiazin-2-yl]methyl}acetamide

New Product


Catalog Number: (RK35011)
Supplier: Restek
Description: Contains: Chain, Compound (CAS#), % by Weight; C6:00 Methyl caproate (106-70-7), 20; C8:00 Methyl caprylate (111-11-5), 20; C10:00 Methyl caprate (110-42-9), 20; C12:00 Methyl laurate (111-82-0), 20; C14:00 Methyl myristate (124-10-7), 20


Catalog Number: (103008-722)
Supplier: Anaspec Inc
Description: This peptide is derived from the V1 domain of protein kinase C (PKC)d. It inhibits phorbol 12-myristate 13-acetate (PMA)-induced PKCd translocation and activation. Inhibition of PKCd reduces ischemia damage in cardiac and cerebral cells, induces proliferation of fibroblasts, and inhibits graft coronary artery disease in mice.
Sequence:SFNSYELGSL
MW:1116.2 Da
% peak area by HPLC:95
Storage condition:-20° C


Catalog Number: (10290-432)
Supplier: Bioss
Description: eNOS is a calcium/calmodulin dependent enzyme which undergoes several post translational modifications, including acylation with myristate and palmitate, and phosphorylation on numerous residues. As with the other members of the NOS family, eNOS derives the diffusible multifunctional second messenger NO from L arginine through a series of reactions in which L citrulline is an intermediate. eNOS plays an important role in controlling vascular tone, platelet aggregation, and cardiac myocyte function.


Catalog Number: (89366-880)
Supplier: Genetex
Description: Rabbit polyclonal antibody to Noxa


Catalog Number: (10290-256)
Supplier: Bioss
Description: eNOS is a calcium/calmodulin dependent enzyme which undergoes several post translational modifications, including acylation with myristate and palmitate, and phosphorylation on numerous residues. As with the other members of the NOS family, eNOS derives the diffusible multifunctional second messenger NO from L arginine through a series of reactions in which L citrulline is an intermediate. eNOS plays an important role in controlling vascular tone, platelet aggregation, and cardiac myocyte function.


Catalog Number: (89296-334)
Supplier: Genetex
Description: Goat Polyclonal antibody to Noxa


Catalog Number: (89271-428)
Supplier: Genetex
Description: Rabbit Polyclonal antibody to Noxa


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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