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Phorbol 12-myristate 13-acetate ≥98% (by HPLC)

Supplier: Adipogen

Description: Most commonly-used phorbol ester. Binds to and activates protein kinase C (PKC) at nM concentrations. Induces cell growth arrest through a variety of pathways including the mitogen-activated protein kinases (MAPKs), p38 and c-Jun N-terminal kinase (JNK) pathways mediated by cyclin dependent kinase (CDK) inhibitors such as p21WAF1/CIP1, p27KIP1, p15 and p16. Potent mouse skin tumor promoter. Promoter of inducible NOS (iNOS; NOS II). Apoptosis inducer. Potential effective cancer therapeutic agent. Inhibitor of anti-lipolytic activity of insulin.

TRC 1-Amino-2-methylindoline

Catalog Number: (77977-520)

Supplier: LGC Standards

Description: TRC 1-Amino-2-methylindoline

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Anti-PMAIP1 Mouse Monoclonal Antibody [clone: 114C307]

Catalog Number: (89367-202)

Supplier: Genetex

Description: Recently a BH3 only member of the Bcl2 family has been identified in human and mouse and designated as Noxa (for damage). The expression of the Noxa gene involves direct activation of its promoter by p53. Increased expression of Noxa protein occurs in normal thymocytes but not in p53 deficient thymocytes. Noxa cDNA codes for a 103 amino acid protein. The co-immunoprecipitation data suggest that Noxa protein may interact with proteins belonging to the Bcl2 family, such as, BclXL and Mcl1. It has also been shown that blocking the endogenous Noxa induction results in the suppression of apoptosis. Treatment of cells with Noxa antisense oligonucleotides blocks radiation induced apoptosis suggesting that Noxa may represent a mediator of p53 dependent apoptosis.

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FAME #3 Mix (5 components), Restek

Catalog Number: (RK35012)

Supplier: Restek

Description: Contains: Chain, Compound (CAS#), % by Weight; C8:00 Methyl caprylate (111-11-5), 20%; C10:00 Methyl caprate (110-42-9), 20%; C12:00 Methyl laurate (111-82-0), 20%; C14:00 Methyl myristate (124-10-7), 20%; C16:00 Methyl palmitate (112-39-0), 20%

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FAME #8 Mix (5 components), Restek

Catalog Number: (RK35017)

Supplier: Restek

Description: Contains: Chain, Compound (CAS#), % by Weight; C11:00 Methyl undecanoate (1731-86-8), 20%; C12:00 Methyl laurate (111-82-0), 20%; C13:00 Methyl tridecanoate (1731-88-0), 20%; C14:00 Methyl myristate (124-10-7), 20%; C15:00 Methyl pentadecanoate (7132-64-1), 20%

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Melanocyte Growth Medium, PromoCell

Supplier: Promocell

Description: The PromoCell Melanocyte Growth Medium is a serum-free, PMA (Phorbol Myristate Acetate) containing medium optimized for the cultivation of human melanocytes

Cell Stimulation Cocktail, Tonbo Biosciences

Catalog Number: (10208-548)

Supplier: Tonbo Biosciences

Description: Cell stimulation cocktail is a ready to use cocktail that can be used for polyclonal cell activation. It is composed of the phorbol ester, PMA (Phorbol 12-Myristate 13-Acetate), a calcium ionophore (Ionomycin), and the protein transport inhibitors Brefeldin A and Monensin. It can be used to elicit cytokine production and retention in a variety of cell types allowing for detection of intracellular protein by flow cytometry.

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Anti-eNOS Ser1176 Rabbit Polyclonal Antibody

Catalog Number: (77440-410)

Supplier: Bioss

Description: eNOS is a calcium/calmodulin dependent enzyme which undergoes several post translational modifications, including acylation with myristate and palmitate, and phosphorylation on numerous residues. As with the other members of the NOS family, eNOS derives the diffusible multifunctional second messenger NO from L arginine through a series of reactions in which L citrulline is an intermediate. eNOS plays an important role in controlling vascular tone, platelet aggregation, and cardiac myocyte function.

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TRC (Z)-2-(2-Aminothiazol-4-yl)-2-(hydroxyimino)-N-{[(2RS,5RS)-5-methyl-7-oxo-2,4,5,7-tetrahydro-1H-furo[3,4-d][1,3]thiazin-2-yl]methyl}acetamide

Catalog Number: (77977-392)

Supplier: LGC Standards

Description: TRC (Z)-2-(2-Aminothiazol-4-yl)-2-(hydroxyimino)-N-{[(2RS,5RS)-5-methyl-7-oxo-2,4,5,7-tetrahydro-1H-furo[3,4-d][1,3]thiazin-2-yl]methyl}acetamide

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FAME #2 Mix (5 components), Restek

Catalog Number: (RK35011)

Supplier: Restek

Description: Contains: Chain, Compound (CAS#), % by Weight; C6:00 Methyl caproate (106-70-7), 20; C8:00 Methyl caprylate (111-11-5), 20; C10:00 Methyl caprate (110-42-9), 20; C12:00 Methyl laurate (111-82-0), 20; C14:00 Methyl myristate (124-10-7), 20

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delta PKC (8-17)

Catalog Number: (103008-722)

Supplier: Anaspec Inc

Description: This peptide is derived from the V1 domain of protein kinase C (PKC)d. It inhibits phorbol 12-myristate 13-acetate (PMA)-induced PKCd translocation and activation. Inhibition of PKCd reduces ischemia damage in cardiac and cerebral cells, induces proliferation of fibroblasts, and inhibits graft coronary artery disease in mice.
Sequence:SFNSYELGSL
MW:1116.2 Da
% peak area by HPLC:95
Storage condition:-20° C