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Catalog Number: (10751-240)
Supplier: Prosci
Description: RBM35B Antibody: RBM35A, also known as ESRP2, is a mRNA splicing factor that with its related protein RBM35A (ESRP1) are coordinators of an epithelial cell-type-specific splicing program. Both RBM35B and RBM35A are involved in posttranscriptional regulation of a number of genes such as FGFR2, CD44, CTNND1, and ENAH by exerting a differential effect on protein translation via 5' UTRs of mRNAs, suggesting that these proteins are global regulators of an epithelial regulatory network. Loss of this global ESRP-regulated epithelial splicing programme induces the phenotypic changes in cell morphology that are observed during the epithelial-mesenchymal transition.


Supplier: Adipogen
Description: Processes such as transcription, repair and replication that require efficient DNA recognition are dependent on modulation of chromatin structure. Chromatin relaxation is a critical event that occurs during DNA repair and is associated with the negatively charged polymer of adenosine 5'-diphosphate (ADP)-ribose (PAR). PAR is synthesized from nicotinamide adenine dinucleotide (NAD+) by the poly(ADP-ribose) polymerase protein family (PARPs), of which PARP-1 (and to a lesser extent PARP-2) respond to DNA-strand breaks. PARP-1 is selectively activated by DNA strand breaks to catalyze the addition of long branched chains of PAR to a variety of nuclear proteins, most notably PARP itself. The amount of PAR formed in living cells with DNA damage is commensurate with the extent of the damage. Under DNA damage conditions, PAR undergoes a rapid turnover, with a half-life in the range of minutes, as PAR is rapidly hydrolyzed and converted to free ADP-ribose by the enzyme poly(ADP-ribose)glycohydrolase (PARG). PAR regulates not only cell survival and cell-death programmes, but also an increasing number of other biological functions with which novel members of the PARP family have been associated. These include transcriptional regulation, cell division, intracellular trafficking, inflammation and energy metabolism.

Supplier: Eppendorf
Description: The cross-over Eppendorf Centrifuge 5430 combines the small footprint of a microcentrifuge with the versatility of a multipurpose centrifuge. Extremely compact, it can accommodate rotors for microplates and 15/50 ml conical tubes as well as Eppendorf tubes and PCR strips.

Product available on GSA Advantage®

Supplier: Binder
Description: 7381610

Catalog Number: (10154-370)
Supplier: VWR International
Description: The VWR® Traceable® Logger-Trac™ Temperature datalogger is an ideal tool for monitoring material in transit, with a variety of intuitive user-programmable features and functions.

Supplier: Branson Ultrasonics
Description: CPXH Series features 99 minute timer or continuous operation, with heat with degassing capability of up to 99 minutes ideal for sample preparation applications

UL Listed cUL Listed CSA Certified

Supplier: VWR International
Description: VWR® Heated Circulating Baths offer precise temperature control, at temperature ranges from ambient +10° to 200°C (depending on the controller).

Product available on GSA Advantage®

Supplier: Eppendorf
Description: Eppendorf® Xplorer® plus multi-channel electronic pipettes offer the ideal solution for precise, efficient liquid handling in high-throughput applications, with ergonomic design, a user-friendly interface, and programmable modes for quick, reliable pipetting, enhancing reproducibility and minimizing errors.

Environmentally Preferable

Catalog Number: (MSPP-045-074)
Supplier: PROTEIN SIMPLE MS
Description: CAPILLARY ICE3 MICROINJECTOR TRANSFER


Catalog Number: (MSPP-UCT-21121)
Supplier: UNIFIED INFORMATION DEVICES MS
Description: MICROCHIP PROGRAMMABLE W/TEMPERATURE

New Product


Catalog Number: (MSPP-UCT211224)
Supplier: UNIFIED INFORMATION DEVICES MS
Description: MICROCHIP TEMPERATURE PROGRAMMABLE PK24


Catalog Number: (MSPP-704507)
Supplier: Harvard Apparatus
Description: PUMP 11ELITE NANOMITE PROGRAMMABLE


Catalog Number: (MSPP-BS8000120)
Supplier: BRAINTREE SCIENTIFIC INC MS
Description: PUMP SYRINGE PROGRAMMABLE 1-60CC

New Product


Catalog Number: (MSPP-NE-1000)
Supplier: NEW ERA PUMP SYSTEMS INC MS
Description: PUMP DUAL SYRINGE PROGRAMMABLE PUSH-PULL


Catalog Number: (10138-718)
Supplier: PerkinElmer
Description: PROGRAMMABLE ON-COLUMN INJECTOR STARTER


Catalog Number: (MSPP-NE-500)
Supplier: NEW ERA PUMP SYSTEMS INC MS
Description: SYRINGE PUMP OEM PROGRAMMABLE


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organization. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at 1-800-932-5000.
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