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Mouse Recombinant EG-VEGF (from E. coli)

Supplier: Peprotech
Description: EG-VEGF is a secreted angiogenetic mitogen growth factor expressed in the steroidogenic glands, ovary, testis, adrenal gland, and placenta. EG-VEGF induces proliferation, migration, and fenestration (formation of membrane discontinuities) in capillary endothelial cells derived from endocrine glands. The murine EG-VEGF gene codes for a 105 amino acid polypeptide containing an N-terminal signal sequence of 19 amino acids. Recombinant Murine EG-VEGF is a 9.6 kDa protein consisting of 86 amino acid residues, including ten cysteine residues that potentially form five pairs of intra-molecular disulfide bonds.

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Anti-KDR Rabbit Polyclonal Antibody (Cy5.5®)

Catalog Number: (10344-100)
Supplier: Bioss
Description: Hemangioblast MarkerVascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas. [provided by RefSeq, May 2009].
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Anti-KDR Rabbit Polyclonal Antibody (Cy7®)

Catalog Number: (10344-102)
Supplier: Bioss
Description: Hemangioblast MarkerVascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas. [provided by RefSeq, May 2009].
Product Image-14233-472

SGE GC Column, BPX1, Trajan Scientific and Medical

Supplier: Trajan Scientific and Medical
Description: These non-polar columns are specifically designed for high temperature hydrocarbon analysis.

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Bradykinin

Supplier: Adipogen
Description: Pro-inflammatory peptide, acting through G-protein-coupled receptors. Endogenous bradykinin receptor agonist that displays selectivity for B2 over B1 receptors. Endogenously formed following pathophysiological stimuli such as inflammation, tissue damage or anoxia. Activator of endothelial nitric oxide synthase (eNOS; NOS III). Reduces blood pressure by inducing the release of prostacyclin, nitric oxide and endothelium-derived hyperpolarizing factor. Plays an important role in the regulation of fluid and electrolyte balance, non-vascular smooth muscle contraction, vasodilation and capillary permeability.

Product Image-AG9910035200

Barrel Nebulizers, Impact Beads and Supplies for Mark V, VI and 7 Spray Chambers

Supplier: AGILENT TECHNOLOGIES, INC (CSD)
Description: Barrel nebulizers for Agilent AA instruments that feature the Mark V or Mark VI atomization system. The adjustable impact bead in the flame atomization system helps aerosol formation.

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Liquid Waveguide Capillary Cells

Supplier: WORLD PRECISION INSTRUMENTS LLC
Description: UV/VIS/NIR absorbance spectroscopy is governed by Beer’s Law, where the absorbance signal is proportional to chemical concentration, light path length and the compound’s specific molar absorption coefficient.

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Product Image-95057-297

MiniCollect® Serum and Plasma Tubes, Greiner Bio-One

Supplier: Greiner Bio-One
Description: Tubes are suitable for collection, transport, and processing of capillary blood samples from infants, toddlers, children, geriatric patients, and patients in intensive care.

Certificates Product available on GSA Advantage®

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XYZ Goniometer Head Kits and Components, Rigaku

Supplier: Rigaku Reagents
Description: XYZ Goniometer Heads feature a IUCr standard goniometer mount for compatibility with most goniometers.

Product Image-60361-802

SGE GC Column, BPX70, Trajan Scientific and Medical

Supplier: Trajan Scientific and Medical
Description: MS-premium, high-polarity columns feature low bleed and are designed for fatty acid methyl ester (FAME) analysis.

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Accessories for MiniCollect® Serum and Plasma Tubes, Greiner Bio-One

Catalog Number: (95057-307)
Supplier: Greiner Bio-One
Description: Funnel, to be used with Greiner MiniCollect Blood Collection Tubes, 100 per pack, 1000 per case

Certificates Product available on GSA Advantage®


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CrossLab Tools and Other Spray Chamber Supplies, Agilent Technologies

Supplier: AGILENT TECHNOLOGIES, INC (CSD)
Description: Spray chamber tools help with routine maintenance of the Mark 7 flame atomization system.

Product Image-38007-080

Ashless Quantitative Paper, Grade 54, Ahlstrom

Supplier: Ahlstrom
Description: Ahlstrom Grade 54 is a fast filtering ashless (Ash 0.007%) filter paper suitable for routine quantitative gravimetric techniques.

Product Image-14705-012

Caraway Capillary Tubes, Kimble Chase, DWK Life Sciences

Supplier: DWK Life Sciences (KIMBLE)
Description: These Caraway tubes are manufactured with tapered tips for easy collection of micro blood samples.

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Anti-C4A, C4B Mouse Monoclonal Antibody [clone: SPM545]

Catalog Number: (76195-346)
Supplier: Prosci
Description: This mAb is specific to Complement 4d (C4d) and it reacts with the secreted as well as cell-bound C4d. C4d is a degradation product of the activated complement factor C4b. Complement 4b is typically activated by binding of Abs to specific target molecules. Following activation and degradation of the C4 molecule, thio-ester groups are exposed, which allow transient, covalent binding of the degradation product Complement 4d to endothelial cell surfaces and extracellular matrix components of vascular basement membranes near the sites of C4 activation. The presence of C4d in peritubular capillaries is a key indicator for acute humoral (i.e. antibody-mediated) rejection of kidney, heart, pancreas and lung allografts. As an established marker of antibody-mediated acute renal allograft rejection and its proclivity for endothelium, this component can be detected in peritubular capillaries in chronic renal allograft rejection as well as hyperacute rejection, acute vascular rejection, acute cellular rejection, and borderline rejection. It has been shown to be a significant predictor of transplant kidney graft survival. Anti-C4d, combined with anti-C3d, can be utilized as a tool for diagnosis of allograft rejection that may warrant a prompt and aggressive anti-rejection treatment.
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Anti-C4A Mouse Monoclonal Antibody [clone: C4D204]

Catalog Number: (76195-430)
Supplier: Prosci
Description: This antibody is specific to Complement 4d (C4d) and it reacts with the secreted as well as cell-bound protein. C4d is a degradation product of the activated complement factor C4b. Complement 4b is typically activated by binding of antibodies to specific target molecules. Following activation and degradation of the C4 molecule, thio-ester groups are exposed, which allow transient, covalent binding of the degradation product C4d to endothelial cell surfaces and extracellular matrix components of vascular basement membranes near the sites of C4 activation. The presence of C4d in peritubular capillaries is a key indicator for acute humoral (i.e. antibody-mediated) rejection of kidney, heart, pancreas and lung allografts. As an established marker of antibody-mediated acute renal allograft rejection and its proclivity for endothelium, this component can be detected in peritubular capillaries in chronic renal allograft rejection as well as hyperacute rejection, acute vascular rejection, acute cellular rejection, and borderline rejection. C4d has been shown to be a significant predictor of transplant kidney graft survival. C4d antibody, combined with antibody to C3d, can be utilized as a tool for diagnosis of allograft rejection that may warrant a prompt and aggressive anti-rejection treatment.
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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