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Product Image-77665-474

Microinjection Syringe Pumps

Supplier: WORLD PRECISION INSTRUMENTS LLC
Description: The UMP3 (UltraMicroPump3) is a versatile microinjection syringe pump paired with microsyringes to deliver microliter-level volumes. The UMP3 is optimal for applications requiring precise, targeted injections of extremely low-volume samples. With its touchscreen controller, our UMP3 can deliver or withdraw as little as 25 nl (using 10 µl syringe with 60 mm stroke length).

New Product

Image Unavailable-10001-652

Biotin-CF® 640R fluorescent dye

Catalog Number: (10001-652)
Supplier: Biotium
Description: Potential applications of Biotin-CF® dye include detection of biotin binding sites and the degree of biotinylation of proteins, and for the measurement of avidin and streptavidin in crude biological samples. In addition, biotin-CF® dye can be used as a polar tracer by microinjection to study the morphology of cells. CF® dyes are very photostable which make them suitable for studies where prolonged exposure to light may be necessary.
Image Unavailable-89139-202

FURA-2 pentapotassium salt ≥95% (by HPLC) fluorescent indicator, for calcium determination

Catalog Number: (89139-202)
Supplier: Biotium
Description: Fura-2, pentapotassium salt is a ratiometric fluorescent dye that binds to free intracellular calcium. It is membrane-impermeant and may be loaded into cells via microinjection or scrape loading.
Image Unavailable-10098-648

Biotin-CF® 568 fluorescent dye

Catalog Number: (10098-648)
Supplier: Biotium
Description: Potential applications of Biotin-CF® dye include detection of biotin binding sites and the degree of biotinylation of proteins, and for the measurement of avidin and streptavidin in crude biological samples. In addition, biotin-CF® dye can be used as a polar tracer by microinjection to study the morphology of cells. CF® dyes are very photostable which make them suitable for studies where prolonged exposure to light may be necessary.
Image Unavailable-10430-094

Anti-XAB2 Rabbit Polyclonal Antibody (Cy7®)

Catalog Number: (10430-094)
Supplier: Bioss
Description: XAB2 protein (XPA binding protein 2) was first identified through its interaction with XPA, a key factor in nucleotide excision repair pathways. XAB2 therefore appears to be involved in transcription coupled DNA repair and transcription. Immunoprecipitation experiments have also demonstrated that a fraction of XAB2 interacts with the transcription coupled repair specific proteins CSA and CSB as well as with RNA polymerase II. Microinjection experiments with XAB2 resulted in the inhibition of both transcription coupled repair and transcription.
Image Unavailable-10430-096

Anti-XAB2 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalog Number: (10430-096)
Supplier: Bioss
Description: XAB2 protein (XPA binding protein 2) was first identified through its interaction with XPA, a key factor in nucleotide excision repair pathways. XAB2 therefore appears to be involved in transcription coupled DNA repair and transcription. Immunoprecipitation experiments have also demonstrated that a fraction of XAB2 interacts with the transcription coupled repair specific proteins CSA and CSB as well as with RNA polymerase II. Microinjection experiments with XAB2 resulted in the inhibition of both transcription coupled repair and transcription.
Image Unavailable-89139-478

Calcein, high purity

Catalog Number: (89139-478)
Supplier: Biotium
Description: is a highly negative charged, water-soluble fluorescein derivative. Its fluorescence is nearly independent of pH in the range between 6.5 and 12. The dye can be introduced into cells by microinjection and is useful for cell tracing and the study of cell membrane integrity and fusion.
Image Unavailable-10430-076

Anti-XAB2 Rabbit Polyclonal Antibody

Catalog Number: (10430-076)
Supplier: Bioss
Description: XAB2 protein (XPA binding protein 2) was first identified through its interaction with XPA, a key factor in nucleotide excision repair pathways. XAB2 therefore appears to be involved in transcription coupled DNA repair and transcription. Immunoprecipitation experiments have also demonstrated that a fraction of XAB2 interacts with the transcription coupled repair specific proteins CSA and CSB as well as with RNA polymerase II. Microinjection experiments with XAB2 resulted in the inhibition of both transcription coupled repair and transcription.
Image Unavailable-77661-906

Footswitch for Micro-Controller

Catalog Number: (77661-906)
Supplier: WORLD PRECISION INSTRUMENTS LLC
Description: Hands-free activation of microinjection pump.

New Product


Product Image-10100-420

Anti-GLE1 Rabbit Polyclonal Antibody

Catalog Number: (10100-420)
Supplier: Prosci
Description: GLE1 is a predicted 75-kDa polypeptide with high sequence and structure homology to yeast Gle1p, which is nuclear protein with a leucine-rich nuclear export sequence essential for poly (A)+RNA export. Inhibition of human GLE1L by microinjection of antibodies against GLE1L in HeLa cells resulted in inhibition of poly (A)+RNA export. Immunoflourescence studies show that GLE1L is localized at the nuclear pore complexes. This localization suggests that GLE1L may act at a terminal step in the export of mature RNA messages to the cytoplasm.This gene encodes a predicted 75-kDa polypeptide with high sequence and structure homology to yeast Gle1p, which is nuclear protein with a leucine-rich nuclear export sequence essential for poly (A)+RNA export. Inhibition of human GLE1L by microinjection of antibodies against GLE1L in HeLa cells resulted in inhibition of poly (A)+RNA export. Immunoflourescence studies show that GLE1L is localized at the nuclear pore complexes. This localization suggests that GLE1L may act at a terminal step in the export of mature RNA messages to the cytoplasm. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Image Unavailable-10072-554

Human Recombinant Klf4-Tat (from HEK293 Cells)

Catalog Number: (10072-554)
Supplier: Prosci
Description: KLF4 is a member of the Kruppel-like factor (KLF) family of zinc finger transcription factors. Members of this family have in common 3 contiguous C2H2-type zinc fingers at the carboxyl terminus that comprise the DNA-binding domain. KLF4 is highly expressed in skin and gut epithelial tissues, but is also found in various other cells and tissues, including vascular endothelial cells, lymphocytes, lung, and testis. It is an important regulator of the cell cycle, transcription, and cell differentiation. Together with Sox2, Oct4, and cMyc, KLF4 can induce the reprogramming of primary human fibroblasts to a pluripotent state. KLF4 and other transcription factors can be introduced into cells by DNA transfection, viral infection, or microinjection. Protein transduction using TAT fusion proteins represents an alternative methodology for introducing transcription factors into primary as well as transformed cells. Recombinant human KLF4-TAT is a 51.7 kDa protein containing 483 amino acid residues, including 13- residue C-terminal TAT peptide.
Image Unavailable-100242-988

Anti-Phosphotyrosine Mouse Monoclonal Antibody (FITC (Fluorescein Isothiocyanate)) [clone: PY20]

Catalog Number: (100242-988)
Supplier: Southern Biotechnology
Description: Protein tyrosine residues are phosphorylated as a result of intracellular protein kinase activation (e.g., via growth factors) during normal growth and development and in oncogenesis. The most abundant population of target proteins for tyrosine phosphorylation is cell surface glycoproteins. Antibodies to phosphotyrosine enable the detection, isolation, and characterization of proteins containing phosphotyrosine. The monoclonal antibody PY20 prevents internalization of activated receptors (e.g., EGFR) when microinjected into cells. The affinity of PY20 for phosphotyrosine is approximately 10-6 to 10-7 M. PY20 binding to phosphorylated tyrosines can be inhibited by free phosphotyrosine and phenylphosphate but not by phosphoserine, phosphothreonine, or free phosphate.
Image Unavailable-76117-690

Anti-XAB2 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalog Number: (76117-690)
Supplier: Bioss
Description: XAB2 protein (XPA binding protein 2) was first identified through its interaction with XPA, a key factor in nucleotide excision repair pathways. XAB2 therefore appears to be involved in transcription coupled DNA repair and transcription. Immunoprecipitation experiments have also demonstrated that a fraction of XAB2 interacts with the transcription coupled repair specific proteins CSA and CSB as well as with RNA polymerase II. Microinjection experiments with XAB2 resulted in the inhibition of both transcription coupled repair and transcription.
Image Unavailable-76116-230

Anti-XAB2 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (76116-230)
Supplier: Bioss
Description: XAB2 protein (XPA binding protein 2) was first identified through its interaction with XPA, a key factor in nucleotide excision repair pathways. XAB2 therefore appears to be involved in transcription coupled DNA repair and transcription. Immunoprecipitation experiments have also demonstrated that a fraction of XAB2 interacts with the transcription coupled repair specific proteins CSA and CSB as well as with RNA polymerase II. Microinjection experiments with XAB2 resulted in the inhibition of both transcription coupled repair and transcription.
Product Image-77664-816

SMARTouch™ Microinjection Syringe Pump Controller

Catalog Number: (77664-816)
Supplier: WORLD PRECISION INSTRUMENTS LLC
Description: The touch-screen display on WPI's MICRO2T SMARTouch™ controller offers an intuitive, user-friendly interface. Our MICRO2T allows for simultaneous control of the UMP3 syringe pump.

New Product


Product Image-10200-022

FCS2® Open Mode Adapter, Bioptechs Inc.®

Catalog Number: (10200-022)
Supplier: BIOPTECHS INC.
Description: The white, top portion of a FCS2® without perfusion ports, which enables the FCS2® to be assembled without the microaqueduct slide
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at 1-800-932-5000.
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