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Product Image-77512-598

Rat PYGL (Glycogen Phosphorylase, Liver) ELISA Kit

Catalog Number: (77512-598)
Supplier: AFG BIOSCIENCE LLC
Description: 36246968

New Product


Image Unavailable-89361-254

Anti-GYS1 Rabbit Polyclonal Antibody

Catalog Number: (89361-254)
Supplier: Genetex
Description: Human muscle glycogen synthase (GS) is responsible for the biosynthesis of glycogen from phosphorylated glucose units. Mammalian liver and muscle contain GS consisting of four subunits with a total molecular weight of 360,000. GS is subject to regulation through both allosteric and covalent modification and occurs in two forms: the phosphorylated inactive form, and the dephosphorylated active form. GS is inactivated by the serine/threonine kinase called glycogen synthase kinase-3b that mainly functions to phosphorylate muscle glycogen synthase. This antibody is specific for the phosphorylated form of GS at Ser 640. Phosphorylation of GS at S640 has been associated with Antiphospholipid Antibody Syndrome.
Image Unavailable-76082-730

Anti-PDPK1 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalog Number: (76082-730)
Supplier: Bioss
Description: PDK1 (3 Phosphoinositide Dependent Protein Kinase 1) phosphorylates AGC kinases. PDK1 activates conventional PKC and PKC zeta through phosphorylation of critical threonine residues in the activation loop. PDK1 also phosphorylates Protein Kinase B (PKB) at threonine 308 in the presence of phosphatidylinositol-3,4,5-trisphosphate. Active Akt inactivates Glycogen Synthase Kinase 3 (GSK3), eventually leading to the dephosphorylation and activation of Glycogen synthase and the stimulation of Glycogen synthesis. Because of the role that PDK plays in insulin-induced Glycogen synthesis and PKC activation it is a potentially important target for metabolic drug research. There are three named isoforms.
Image Unavailable-76080-704

Anti-PDPK1 Ser393 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalog Number: (76080-704)
Supplier: Bioss
Description: PDK1 (3 Phosphoinositide Dependent Protein Kinase 1) phosphorylates AGC kinases. PDK1 activates conventional PKC and PKC zeta through phosphorylation of critical threonine residues in the activation loop. PDK1 also phosphorylates Protein Kinase B (PKB) at threonine 308 in the presence of phosphatidylinositol-3,4,5-trisphosphate. Active Akt inactivates Glycogen Synthase Kinase 3 (GSK3), eventually leading to the dephosphorylation and activation of Glycogen synthase and the stimulation of Glycogen synthesis. Because of the role that PDK plays in insulin-induced Glycogen synthesis and PKC activation it is a potentially important target for metabolic drug research. There are three named isoforms.
Image Unavailable-10391-242

Anti-GYG1 Rabbit Polyclonal Antibody (Cy5.5®)

Catalog Number: (10391-242)
Supplier: Bioss
Description: This gene encodes a member of the glycogenin family. glycogenin is a glycosyltransferase that catalyzes the formation of a short glucose polymer from uridine diphosphate glucose in an autoglucosylation reaction. This reaction is followed by elongation and branching of the polymer, catalyzed by glycogen synthase and branching enzyme, to form glycogen. This gene is expressed in muscle and other tissues. Mutations in this gene result in glycogen storage disease XV. This gene has pseudogenes on chromosomes 1, 8 and 13 respectively. Alternatively spliced transcript variants encoding different isoforms have been identified.[provided by RefSeq, Sep 2010].
Image Unavailable-101777-840

ω,4-Dibromoacetophenone 98

Catalog Number: (101777-840)
Supplier: Matrix Scientific
Description: ω,4-Dibromoacetophenone 98

SDS


Image Unavailable-10346-590

Anti-PDPK1 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (10346-590)
Supplier: Bioss
Description: PDK1 (3 Phosphoinositide Dependent Protein Kinase 1) phosphorylates AGC kinases. PDK1 activates conventional PKC and PKC zeta through phosphorylation of critical threonine residues in the activation loop. PDK1 also phosphorylates Protein Kinase B (PKB) at threonine 308 in the presence of phosphatidylinositol-3,4,5-trisphosphate. Active Akt inactivates Glycogen Synthase Kinase 3 (GSK3), eventually leading to the dephosphorylation and activation of Glycogen synthase and the stimulation of Glycogen synthesis. Because of the role that PDK plays in insulin-induced Glycogen synthesis and PKC activation it is a potentially important target for metabolic drug research. There are three named isoforms.
Image Unavailable-10298-256

Anti-GYG1 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalog Number: (10298-256)
Supplier: Bioss
Description: Glycogen synthesis is initiated by the autoglucosylation of Glycogenin-1. Specifically, Glycogenin-1 glucosylates itself to begin the synthesis of Glycogen in mammalian skeletal muscle. It acts as the primer to which further glucose monomers may be added. All of the Glycogenin-1 molecules contain at least one glucosyl residue before autoglucosylation begins. The first step of the Glycogen synthesis occurs when a glucose molecule from UDP-glucose binds to the hydroxyl group of Tyr 194 on the Glycogenin-1 molecule. Using its glucosyltransferase activity, Glycogenin-1 adds more glucoses, each one coming from UDP-glucose. The glycosylation process reaches a plateau when five new glucose residues have been added, at which point Glycogen synthase (GS) takes over and further elongates the chain. Glycogenin-1 remains covalently attached to the reducing end of the Glycogen molecule.
Image Unavailable-10298-254

Anti-GYG1 Rabbit Polyclonal Antibody (Cy7®)

Catalog Number: (10298-254)
Supplier: Bioss
Description: Glycogen synthesis is initiated by the autoglucosylation of Glycogenin-1. Specifically, Glycogenin-1 glucosylates itself to begin the synthesis of Glycogen in mammalian skeletal muscle. It acts as the primer to which further glucose monomers may be added. All of the Glycogenin-1 molecules contain at least one glucosyl residue before autoglucosylation begins. The first step of the Glycogen synthesis occurs when a glucose molecule from UDP-glucose binds to the hydroxyl group of Tyr 194 on the Glycogenin-1 molecule. Using its glucosyltransferase activity, Glycogenin-1 adds more glucoses, each one coming from UDP-glucose. The glycosylation process reaches a plateau when five new glucose residues have been added, at which point Glycogen synthase (GS) takes over and further elongates the chain. Glycogenin-1 remains covalently attached to the reducing end of the Glycogen molecule.
Image Unavailable-10298-178

Anti-GYG1 Rabbit Polyclonal Antibody

Catalog Number: (10298-178)
Supplier: Bioss
Description: Glycogen synthesis is initiated by the autoglucosylation of Glycogenin-1. Specifically, Glycogenin-1 glucosylates itself to begin the synthesis of Glycogen in mammalian skeletal muscle. It acts as the primer to which further glucose monomers may be added. All of the Glycogenin-1 molecules contain at least one glucosyl residue before autoglucosylation begins. The first step of the Glycogen synthesis occurs when a glucose molecule from UDP-glucose binds to the hydroxyl group of Tyr 194 on the Glycogenin-1 molecule. Using its glucosyltransferase activity, Glycogenin-1 adds more glucoses, each one coming from UDP-glucose. The glycosylation process reaches a plateau when five new glucose residues have been added, at which point Glycogen synthase (GS) takes over and further elongates the chain. Glycogenin-1 remains covalently attached to the reducing end of the Glycogen molecule.
Product Image-76707-666

Mouse Glycogen Synthase Kinase 3 Beta (GSK3B) ELISA Kit

Catalog Number: (76707-666)
Supplier: AFG BIOSCIENCE LLC
Description: 36246968
Product Image-76703-652

Mouse Glycogen [starch] Synthase, Liver(GYS2) ELISA Kit

Catalog Number: (76703-652)
Supplier: AFG BIOSCIENCE LLC
Description: 36246968
Image Unavailable-10346-588

Anti-PDPK1 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalog Number: (10346-588)
Supplier: Bioss
Description: PDK1 (3 Phosphoinositide Dependent Protein Kinase 1) phosphorylates AGC kinases. PDK1 activates conventional PKC and PKC zeta through phosphorylation of critical threonine residues in the activation loop. PDK1 also phosphorylates Protein Kinase B (PKB) at threonine 308 in the presence of phosphatidylinositol-3,4,5-trisphosphate. Active Akt inactivates Glycogen Synthase Kinase 3 (GSK3), eventually leading to the dephosphorylation and activation of Glycogen synthase and the stimulation of Glycogen synthesis. Because of the role that PDK plays in insulin-induced Glycogen synthesis and PKC activation it is a potentially important target for metabolic drug research. There are three named isoforms.
Image Unavailable-77558-008

Synthetic GS Peptide

Catalog Number: (77558-008)
Supplier: Sino Biological
Description: The GS peptide sequence (PLSRTLSVSS) is derived from an N to terminus of glycogen synthase and is suitable for use as the substrate for DCAMKL1 and CAMKII family.

New Product


Product Image-101411-222

McManus’ Method (PAS) for Glycogen, Electron Microscopy Sciences

Supplier: Electron Microscopy Sciences
Description: Coleman's Feulgen

Minority or Woman-Owned Business Enterprise

Image Unavailable-10417-344

Anti-PDPK1 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (10417-344)
Supplier: Bioss
Description: PDK1 (3 Phosphoinositide Dependent Protein Kinase 1) phosphorylates AGC kinases. PDK1 activates conventional PKC and PKC zeta through phosphorylation of critical threonine residues in the activation loop. PDK1 also phosphorylates Protein Kinase B (PKB) at threonine 308 in the presence of phosphatidylinositol-3,4,5-trisphosphate. Active Akt inactivates Glycogen Synthase Kinase 3 (GSK3), eventually leading to the dephosphorylation and activation of Glycogen synthase and the stimulation of Glycogen synthesis. Because of the role that PDK plays in insulin-induced Glycogen synthesis and PKC activation it is a potentially important target for metabolic drug research. There are three named isoforms.
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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