You Searched For: Hepta-O-acetyl-β-lactosyl azide

Description: 1-(5-(4-Amino-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-4-fluoroindolin-1-yl)-2-(6-methylpyridin-2-yl)ethanone, Purity: 98%, CAS Number: 1337532-29-2, Appearance: White to Yellow to Brown Solid, Storage: Keep in dark place, Inert atmosphere, Store in freezer, under -20 C, Size: 1mg

Catalog Number: 77151-710

Supplier: Ambeed

Sale

Description: Anti-GSK-249320 Recombinant Antibody

Catalog Number: 76763-596

Supplier: Prosci

Sale

Description: Chemical probes can be used to help establish the relationship between a molecular target and the broader biological consequences of modulating that target in cells or organisms.

Catalog Number: TS468211000

Supplier: Thermo Scientific Chemicals

New Product Sale

Description: Anti-GSK-1223249 Recombinant Antibody

Catalog Number: 76756-316

Supplier: Prosci

Sale

Description: 3-((2-(Pyridin-2-yl)-6-(1,2,4,5-tetrahydro-3H-benzo[d]azepin-3-yl)pyrimidin-4-yl)amino)propanoic acid, Purity: 98%, CAS Number: 1373422-53-7, Appearance: White to off-white powder or crystals, Storage: Keep in dark place, Inert atmosphere, 2-8 C, Size: 5mg

Catalog Number: 77171-204

Supplier: Ambeed

Sale

Description: The Recombinant Human Active GSK-3 beta Protein from R&D Systems is derived from Sf 9 (baculovirus). The Recombinant Human Active GSK-3 beta Protein has been validated for the following applications: Bioactivity.

Catalog Number: 220009-336

Supplier: R&D Systems

Sale

Description: Glycogen Synthase Kinase 3β (GSK-3β) is a unique serine/threonine kinase that is inactivated by phosphorylation. In response to insulin binding, PKB/AKT phosphorylates GSK-3β on serine 9, which prevents GSK-3β from phosphorylating glycogen synthase. Unphosphorylated glycogen synthase is active and able to synthesize glycogen. GSK-3β is also unique in that it requires a substrate that has been phosphorylated by a distinct kinase before it can phosphorylate the substrate. This phosphate priming mechanism explains why phosphorylation of serine 9 inactivates GSK-3β. The phosphorylated serine binds to the GSK-3β priming phosphate position and prevents binding of alternative substrates. In addition to insulin signaling, GSK-3β participates in the Wnt signaling pathway, where it forms a complex with axin, beta-catenin and adenomatous polyposis coli (APC) protein. In the presence of Wnts, GSK-3β is unable to phosphorylate beta-catenin, which leads to stabilization of beta-catenin. The Wnt pathway inactivates GSK-3β via the proteins, Dishevelled and FRAT, which disrupt the interaction of GSK-3β with axin, beta-catenin, and APC. Clinically, there is considerable interest in GSK-3β inhibitors because they may mimic the effect of insulin or reduce the hyperphosphorylation of Tau that is observed in Alzheimer's Disease.

Catalog Number: 95045-932

Supplier: Enzo Life Sciences

SDS Sale

Description: GSK2830371 ≥98%

Catalog Number: 77616-932

Supplier: Ambeed

New Product Sale

Description: Anti-GSK-2398852 Recombinant Antibody

Catalog Number: 76758-584

Supplier: Prosci

Sale

Description: GSK180736A 97%

Catalog Number: 76647-192

Supplier: Ambeed

New Product Sale

Description: N-((S)-1-Amino-3-(3-fluorophenyl)propan-2-yl)-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)thiophene-2-carboxamide, Purity: 99+%, CAS Number: 1047644-62-1, Appearance: White to off-white powder, Storage: Keep in dark place, Inert atmosphere, Store in freezer, under -20 C, Size: 10mg

Catalog Number: 77234-722

Supplier: Ambeed

Sale

Description: GSK-3β Peptide Inhibitor

Catalog Number: 80603-132

Supplier: MilliporeSigma

SDS Certificates Sale

Description: N-((4,6-Dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-1-isopropyl-3-methyl-6-(6-(4-methylpiperazin-1-yl)pyridin-3-yl)-1H-indole-4-carboxamide, Purity: 98+%, CAS Number: 1346572-63-1, Appearance: White to off-white powder or crystals, Storage: Sealed in dry, Room Temperature, Size: 5mg

Catalog Number: 77116-072

Supplier: Ambeed

Sale

Description: Inhibitor of CDK and GSK

Catalog Number: 89147-538

Supplier: Enzo Life Sciences

Sale

Description: Human Glycogen Synthase Kinase 3(GSK-3) ELISA Kit

Catalog Number: 76711-630

Supplier: AFG Bioscience

Sale

Description: Rat Glycogen Synthase(GSK) ELISA Kit

Catalog Number: 76709-332

Supplier: AFG Bioscience

Sale