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Product Image-103568-352

HemaPrime™ Human Peripheral Blood Mononuclear Cells, Disease State, Cryopreserved

Catalog Number: (103568-352)
Supplier: Charles River Laboratories Cell Solutions
Description: Peripheral blood cells are collected from healthy donors by direct collection or by using the Spectra Optia® Apheresis system. Cell-rich leukapheresis product is extracted using continuous flow centrifugal technology directly into the collection bag.
Image Unavailable-76008-554

VWR® Basic Industrial Beard Covers

Catalog Number: (76008-554)
Supplier: VWR International
Description: VWR® Basic protection industrial beard covers are strong, lightweight, and breathable.

Certificates


Product Image-10819-832

VWR® Extra Shelves for VWR® Standard Series Laboratory Refrigerators

Supplier: VWR International
Description: Includes an extra wire frame shelf made to fit VWR® Standard series laboratory refrigerators. (Includes SLV models).

Product Image-76520-766

Corepoint™ Scientific Plasma Freezers, Horizon Scientific

Supplier: VWR International
Description: These high performance plasma freezers revolutionize plasma storage to deliver optimum temperatures and maximum protection.

Environmentally Preferable

Product Image-97058-226

VWR® General Purpose Digital Laboratory Incubators, 10.8 cubic feet

Supplier: VWR International
Description: General-purpose incubators deliver a degree of temperature uniformity usually found only in more expensive, application specific models.

Small Business Enterprise

Product Image-103701-200

Human Tropoelastin

Catalog Number: (103701-200)
Supplier: ADVANCED BIOMATRIX, INC. MS
Description: Tropoelastin is the precursor to the elastin molecule. Elastin is found in many tissues of the body including the skin, arterial walls and ligaments. Elastin confers strength and elasticity to tissues and organs.

Tropoelastin is not normally available in its native state since it becomes cross-linked immediately after its synthesis by the cell, during its export into the extracellular matrix.

This tropoelastin is produced using recombinant production methods. The product is supplied as a sterile, lyophilized powder containing 1 mg per vial. A Certificate of Analysis is available with the purchase of each product.

Tropoelastin is typically used as a thin coating on tissue culture surfaces. Specific instructions are found in the Directions for Use. This product is generally used in vitro as a substrate scaffold to enhance cell attachment, adherence and proliferation.
Product Image-60825-414

VWR® Culture Tubes, Disposable, Borosilicate Glass

Supplier: VWR International
Description: These tubes are chemically clean and well-suited for general use in chemistry, blood banks, hematology, and other laboratory procedures.

Certificates

Image Unavailable-89232-430

Heracell CO₂ Incubator Technical Services, Thermo Scientific

Supplier: VWR International
Description: Maintaining your laboratory equipment is crucial to the overall productivity of your lab, the long-term performance of your equipment and your total cost of ownership. We offer a variety of support plans to best suit the individual needs of your laboratory. A proactive maintenance strategy can maximize your technology investment by predicting and preventing problems before they occur, and as a result, can extend the life of your instrument, increase the overall productivity of your laboratory, and reduce your total cost-of-ownership. Free up your time, energy and resources to focus on your priorities. All the service options cover different Thermo Scientific CO<sub>2</sub> incubator lines.

Product Image-BDH1176-204L

Xylene (mixture of isomers), low water content 98.5-99.41% (isomers plus ethylbenzene) ACS, VWR Chemicals BDH®

Supplier: VWR International
Description: Suitable for general laboratory use, Histology and low-water applications.

Certificates

Product Image-97043-518

Accessories for General-Purpose and Enzyme Laboratory Freezers, Manual or Auto Defrost

Catalog Number: (97043-518)
Supplier: VWR International
Description: Includes 2 braking and 2 non-braking casters. no assembly required. freezer rests inside retaining walls of platform.

Small Business Enterprise Product available on GSA Advantage®


Product Image-48311-656

VWR® Premium Superfrost® Colorfrost® Microscope Slides

Supplier: VWR International
Description: VWR® Superfrost® and Colorfrost® Micro Slides feature brilliant coloring and a coating that accepts and retains laboratory markings better than comparable products.

Certificates Product available on GSA Advantage®

Product Image-10037-442

VWR® Double Beam UV-Vis Spectrophotometer

Catalog Number: (10037-442)
Supplier: VWR International
Description: A double beam spectrophotometer suitable for a wide range of applications including general research, pharmaceutical, biochemical and clinical laboratory use, new material development, and quality control.
Product Image-89141-828

Anti-CD40 Rabbit Polyclonal Antibody

Supplier: Enzo Life Sciences
Description: CD40 is a 45-50 kDa type I membrane protein and a member of the tumor necrosis factor (TNF) receptor superfamily. CD40 is also known as pb50 or CDW40.  CD40 is expressed primarily by professional antigen-presenting cells and it is also expressed on non-immune cell types. The CD40 expressed by professional antigen-presenting cells plays a critical role in co-stimulation and antigen-presenting cell activation in T cell-dependent immune responses. Signals generated through CD40 in B cells are anti-apoptotic. These signals are also required for T cell-dependent B cell activation and proliferation, isotype switching, up-regulation of costimulatory receptors, germinal center formation and memory generation. CD40 signal transduction is initiated by binding trimeric CD40 ligand (CD40L) which is found on the surface of activated T cells.  CD40 engages several signalling pathways in B cells and these include NF-kB, the mitogen-activated protein kinases p38 and c-Jun N-terminal kinase. The 62 amino acid cytoplasmic domain (CD40c) of CD40 contains two linear TNF-receptor associated factor (TRAF) binding domains. The membrane proximal site of CD40c binds TRAF6 and the membrane distal site binds TRAF1, 2 and 3. CD40c is thought to mediate the CD40-dependant signalling pathways by recruitment of TRAF to this multimerized domain. CD40 ligation has also been shown to stimulate iNOS expression, and therefore NO production, by activating NF-kB in IFN-g treated microglial cells. NO derived from microglia has been implicated in the damage of myelin-producing oligodendrocytes in demyelinating disorders like multiple sclerosis (MS) and neuronal death during Alzheimer’s disease and brain trauma. Increased CD40-CD40 ligation has been implicated in the pathogenesis of several autoimmune inflammatory diseases, such as MS, arthritis and insulin-dependant diabetes.

Product Image-77321-978

VWR® Premium Lab Drawer Kits and Accessories for Fridges and Freezers

Supplier: VWR International
Description: Explore VWR® Premium laboratory acessories to customize your Premium laboratory refrigerators and freezers.

Product Image-10819-894

VWR® Standard Series Freestanding Undercounter Refrigerator and Freezer

Supplier: VWR International
Description: These undercounter laboratory refrigerators and freezers provide versatile cold storage in a space-saving design.

Certificates Environmentally Preferable

Product Image-76491-636

VWR® General Purpose Liquid-In-Glass Thermometer, Red Spirit

Catalog Number: (76491-636)
Supplier: VWR International
Description: These thermometers contain red organic liquid against white back glass and are ideal for use in chemical laboratories, universities, scientific institutions, food and beverage processing, petrochemical laboratories, pharmaceutical industry, medical industry, manufacturers, dairies, breweries and distilleries.
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organization. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at 1-800-932-5000.
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