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Product Image-89177-044

CentriVap® micro IR Vacuum Concentrator, Labconco

Catalog Number: (89177-044)
Supplier: Labconco
Description: With the smallest footprint available, the new CentriVap® micro IR Vacuum Concentrator fits in tight spaces and is ideal for small throughput in molecular biology, proteomics, genomics, genetics, cell biology and drug discovery labs

Product available on GSA Advantage®


Product Image-10291-430

Anti-FMO5 Rabbit Polyclonal Antibody

Catalog Number: (10291-430)
Supplier: Bioss
Description: In contrast with other forms of FMO it does not seem to be a drug-metabolizing enzyme.
Product Image-10109-330

Anti-FMO3 Rabbit Polyclonal Antibody

Catalog Number: (10109-330)
Supplier: Prosci
Description: FMO3 is involved in the oxidative metabolism of a variety of xenobiotics such as drugs and pesticides. It N-oxygenates primary aliphatic alkylamines as well as secondary and tertiary amines. It acts on TMA to produce TMA-N-oxide.
Product Image-10237-716

Anti-ABCB1A Rabbit Polyclonal Antibody

Catalog Number: (10237-716)
Supplier: Bioss
Description: Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells.
Product Image-12777-042

BioCoat™ HTS Caco-2 Assay Systems, PET Membrane, Corning

Catalog Number: (12777-042)
Supplier: Corning
Description: HTS insert plates are arrays of individual cell culture inserts connected by a rigid, robotics-friendly holder. This single-unit design makes insert plates ideal for running automated, high throughput drug transport (Caco-2 cells) cell toxicity studies or cell migration and invasion studies.

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Image Unavailable-ALE491942250MG

Eptifibatide acetate

Supplier: ALADDIN SCIENTIFIC
Description: Product descriptionEptifibatide acetate is a cyclic heptapeptide. It is the member of the class arginin-glycin-aspartat-mimetics. Eptifibatide has a short half-life. The drug decreases the risk of myocardial infarction (MI). Eptifibatide acetate might be associated with thrombocytopenia.

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Product Image-75935-384

Anti-SLC22A17 Rabbit Polyclonal Antibody

Catalog Number: (75935-384)
Supplier: Rockland Immunochemical
Description: The Slc22 family of organic anion and cation transporters (OATs, OCTs, OCTNs) are transmembrane proteins expressed predominantly in kidney and liver. Each contain 12 predicted alpha-helical transmembrane domains (TMDs) and one large extracellular loop between TMDs 1 and 2. Transporters of the SLC22 family function in different ways such as uniporters that mediate facilitated diffusion in either direction (OCTs), as anion exchangers (OAT1, OAT3 and URAT1), and as Na(+)/l-carnitine cotransporter (OCTN2). Slc22 family members participate in the absorption and/or excretion of drugs, xenobiotics, and endogenous compounds in intestine, liver, and kidney, and perform homeostatic functions in brain and heart. Mutations in the Slc22 family may cause specific diseases such as primary systemic carnitine deficiency or idiopathic renal hypouricemia and may change drug absorption or excretion. Recent studies show the expression of Slc22A17 as receptor for Lipocalin 2 is relatively high in hematopoietic stem cells.
Product Image-10108-294

Anti-SLC22A1 Rabbit Polyclonal Antibody

Catalog Number: (10108-294)
Supplier: Prosci
Description: Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. The protein contains twelve putative transmembrane domains and is a plasma integral membrane protein.Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. This gene is one of three similar cation transporter genes located in a cluster on chromosome 6. The encoded protein contains twelve putative transmembrane domains and is a plasma integral membrane protein. Two transcript variants encoding two different isoforms have been found for this gene, but only the longer variant encodes a functional transporter.
Product Image-10104-578

Anti-BPNT1 Rabbit Polyclonal Antibody

Catalog Number: (10104-578)
Supplier: Prosci
Description: BPNT1, also called bisphosphate 3-prime-nucleotidase, or BPntase, is a member of a magnesium-dependent phosphomonoesterase family. Lithium, a major drug used to treat manic depression, acts as an uncompetitive inhibitor of BPntase. The predicted human protein is 92% identical to mouse BPntase. BPntase's physiologic role in nucleotide metabolism may be regulated by inositol signaling pathways. The inhibition of human BPntase may account for lithium-induced nephrotoxicity.BPNT1, also called bisphosphate 3-prime-nucleotidase, or BPntase, is a member of a magnesium-dependent phosphomonoesterase family. Lithium, a major drug used to treat manic depression, acts as an uncompetitive inhibitor of BPntase. The predicted human protein is 92% identical to mouse BPntase. BPntase's physiologic role in nucleotide metabolism may be regulated by inositol signaling pathways. The inhibition of human BPntase may account for lithium-induced nephrotoxicity.
Image Unavailable-102988-064

Andrastin A ≥95% (by HPLC)

Supplier: Adipogen
Description: Mycotoxin. Protein farnesyltransferase (PFTase) inhibitor. Anti-cancer compound. Directly interacts with P-glycoprotein and inhibits the efflux of antitumor agents in drug resistant cells.

Product Image-IC19150291

Anthralin ≥99%, yellow powder

Supplier: MP Biomedicals
Description: Dithranol (1, 8 - dihydroxy-9-anthrone) is also known as anthralin. It is a vital topical antipsoriatic drugs. Dithranol, an athracene derivative, is a free radical generating mitochondrial poison that induces apoptosis in keratinocytes.

Image Unavailable-CH03283-100MG

Ala-Gly-Gly-Gly-OH

Catalog Number: (CH03283-100MG)
Supplier: CHEM-IMPEX INTERNATIONAL, INC
Description:
Ala-Gly-Gly-Gly-OH, also known as A Glycine derivative, is a peptide that plays a significant role in various biochemical applications. This compound is particularly valued in the fields of biochemistry and molecular biology for its ability to serve as a building block in peptide synthesis. Its unique structure allows it to participate in the formation of larger peptides and proteins, making it essential for researchers focused on protein engineering and drug development. Additionally, Ala-Gly-Gly-Gly-OH has been explored for its potential therapeutic applications, including its role in enhancing the stability and efficacy of peptide-based drugs.

Researchers and industry professionals can leverage Ala-Gly-Gly-Gly-OH in the development of novel therapeutic agents, particularly in the areas of cancer treatment and regenerative medicine. Its compatibility with various biochemical assays and its ability to modulate biological activity make it a versatile tool in laboratory settings. Furthermore, its relatively simple synthesis and stability under physiological conditions provide significant advantages over more complex peptides, making it an attractive option for both academic and industrial applications.

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Image Unavailable-76085-100

Anti-ADCY8 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (76085-100)
Supplier: Bioss
Description: This is a membrane-bound, calcium-stimulable adenylyl cyclase. May be involved in learning, in memory and in drug dependence (By similarity).
Product Image-75878-094

Isocitrate Dehydrogenase Assay Kit, BioAssay Systems

Catalog Number: (75878-094)
Supplier: BIOASSAY SYSTEMS
Description: For quantitative colorimetric kinetic determination of isocitrate dehydrogenase activity and evaluation of drug effects on its metabolism
Product Image-76012-150

Anti-GSTM5 Rabbit Polyclonal Antibody

Catalog Number: (76012-150)
Supplier: Prosci
Description: Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Diversification of these genes has occurred in regions encoding substrate-binding domains, as well as in tissue expression patterns, to accommodate an increasing number of foreign compounds.
Product Image-95040-274

Polyadenylic acid (poly-A)

Supplier: Cytiva
Description: Poly(A) (polyadenylic acid) can be used to evaluate the binding of potential therapeutic agents to mRNA in drug development research.

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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