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Catalog Number: (AAJ60355-09)
Supplier: Thermo Scientific Chemicals
Description: A non-steroidal, anti-inflammatory drug (NSAID) with potent inhibitory activity in several models of inflammation

Catalog Number: (10110-228)
Supplier: Prosci
Description: GSTZ1 is a member of the glutathione S-transferase (GSTs) super-family which are important in the detoxification of electrophilic molecules, including carcinogens, mutagens, and several therapeutic drugs, by conjugation with glutathione. This enzyme also plays a significant role in the catabolism of phenylalanine and tyrosine. Thus defects in this enzyme may lead to severe metabolic disorders including alkaptonuria, phenylketonuria and tyrosinaemia.This gene is a member of the glutathione S-transferase (GSTs) super-family which encodes multifunctional enzymes important in the detoxification of electrophilic molecules, including carcinogens, mutagens, and several therapeutic drugs, by conjugation with glutathione. This enzyme also plays a significant role in the catabolism of phenylalanine and tyrosine. Thus defects in this enzyme may lead to severe metabolic disorders including alkaptonuria, phenylketonuria and tyrosinaemia. Several transcript variants of this gene encode multiple protein isoforms.


Catalog Number: (10308-376)
Supplier: Bioss
Description: MRP5 (190-200 kDa) is closely related to MRP4, both lacking the first five membrane spanning regions. MRP5 is a GS-X multi specific organic anion pump (nucleotide analogs). MRP5 may transport DNP-GS and may be inhibited by certain inhibitors of organic anion transport (sulfinpyrazone). MRP5 may also transport organic anions with the anionic moiety of phosphate/phosphonate group, a function which provides the ability to resist against anti cancer drugs 6-MP and thioguanine as well as the anti-HIV drug PMEA.


Catalog Number: (10308-380)
Supplier: Bioss
Description: MRP5 (190-200 kDa) is closely related to MRP4, both lacking the first five membrane spanning regions. MRP5 is a GS-X multi specific organic anion pump (nucleotide analogs). MRP5 may transport DNP-GS and may be inhibited by certain inhibitors of organic anion transport (sulfinpyrazone). MRP5 may also transport organic anions with the anionic moiety of phosphate/phosphonate group, a function which provides the ability to resist against anti cancer drugs 6-MP and thioguanine as well as the anti-HIV drug PMEA.


Supplier: SAMPLING SYSTEMS LTD
Description: The SteriWare range of greduated beakers are ideal for use in the production of drugs, chemicals and cosmetics.

New Product

Catalog Number: (10103-498)
Supplier: Prosci
Description: SULT1C4 catalyzes the sulfate conjugation of many drugs, xenobiotic compounds, hormones, and neurotransmitters. It may be involved in the activation of carcinogenic hyroxylamines. SULT1C4 shows activity towards p-nitrophenol and N-hydroxy-2-acetylamino-fluorene (N-OH-2AAF).Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and length of exons) is similar among family members. This gene encodes a protein that belongs to the SULT1 subfamily, responsible for transferring a sulfo moiety from PAPS to phenol-containing compounds.


Catalog Number: (75929-930)
Supplier: Rockland Immunochemical
Description: Multidrug transporters, such as MFSD1, are membrane proteins that expel a wide spectrum of cytotoxic compounds from the cell and render cells resistant to multiple drugs. The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that include uniporters, symporters, and antiporters. Members of this family are found in all living organisms and are highly represented in bacteria. MFS members are capable of transporting various substrates such as sugars, polyols, drugs, neurotransmitters, amino acids, peptides, and inorganic anions, although most members are substrate-specific. MFS have provided important insight into the mechanism underlying multidrug transport. MFSD1 is still poorly understood.


Catalog Number: (89067-454)
Supplier: Bio-Serv
Description: Most effective oral treatment against a broad spectrum of Helicobacter strains


Supplier: Greiner Bio-One
Description: The new SCREENSTAR microplate is manufactured entirely of cycloolefin, and has been developed for new applications in high-content screening and high-resolution microscopy in drug discovery and research.
Catalog Number: (10294-234)
Supplier: Bioss
Description: In contrast with other forms of FMO it does not seem to be a drug-metabolizing enzyme.


Supplier: Owen Mumford
Description: Veterinary Unifine Pentips Paws Pen Needle, Gauge: 31G, 18mm, are designed to offer comfort for pet animals, Used with injection pens for the delivery of approved drugs, Features: DiamondPoint Technology, OptiFlow Technology, Electropolished

Supplier: Spectrum Chemicals
Description: Poloxamer 181, Surfactant is a nonionic triblock copolymer. It is made up of a main hydrophobic chain of polyoxypropylene bordered on each side by two hydrophilic chains of polyoxyethylene. These surfactants are commonly used in industrial applications, cosmetics, and pharmaceuticals. They have also been evaluated for various drug delivery applications and were shown to sensitize drug resistant cancers to chemotherapy. Ungraded products supplied by Spectrum are indicative of a grade suitable for general industrial use or research purposes and typically are not suitable for human consumption or therapeutic use. These materials may or may not have a Certificate of Analysis available.
Supplier: Bachem Americas
Description: The substrate EALFQ-pNA representing the 2C/3A cleavage site of human rhinovirus-14 (HRV-14) polyprotein was hydrolyzed by human rhinovirus-14 3C protease, which represents an attractive target for antiviral drug development. It exhibited a kcat/Km value of 840 M⁻¹s⁻¹.

Catalog Number: (76638-196)
Supplier: AZENTA US, INC
Description: These storage plates are designed for high density sample collection and storage for a wide array of applications within cell biology, molecular biology and drug discovery. Clear plate, perfect for storage applications.


Supplier: NANOCOMPOSIX, INC.
Description: 80 nm spherical gold nanoparticles for passive adsorption combine strong plasmonic optical properties with surface chemistry designed for passive adsorption. These nanoparticles are used in applications such as immunodiagnostics, lateral flow assays, nanomedicine, drug delivery, biosensors, and more.

New Product

Supplier: AAT BIOQUEST INC
Description: Calcium flux assays are preferred methods in drug discovery for screening G protein coupled receptors (GPCR).

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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