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Catalog Number: (10447-464)
Supplier: Bioss
Description: Binds pre-mRNA and nucleates the assembly of 40S hnRNP particles. Single HNRNPC tetramers bind 230-240 nucleotides. Trimers of HNRNPC tetramers bind 700 nucleotides. May play a role in the early steps of spliceosome assembly and pre-mRNA splicing. Interacts with poly-U tracts in the 3'-UTR or 5'-UTR of mRNA and modulates the stability and the level of translation of bound mRNA molecules.


Catalog Number: (10070-324)
Supplier: Prosci
Description: p53 is a nuclear protein which plays an essential role in the regulation of cell cycle specifically in the transition from G0 to G1. It is found in very low levels in normal cells however in a variety of transformed cell lines in high amounts and believed to contribute to transformation and malignancy. The open reading frame of p53 is 393 amino acids long, with the central region (consisting of amino acids from about 100 to 300) containing the DNA-binding domain. This proteolysis-resistant core is flanked by a C-terminal end mediating oligomerization and an N-terminal end containing a strong transcription activation signal. p53 binds as a tetramer to a PBS (p53-Binding Site) and activates the expression of downstream genes that inhibit growth and/or invasion. p53 binds as a tetramer to a p53-binding site (PBS) and to activate the expression of adjacent genes that inhibit growth and/or invasion. Deletion of one or both p53 alleles reduces the expression of tetramers, resulting in decreased expression of the growth inhibitory genes


Catalog Number: (10072-356)
Supplier: Prosci
Description: The tetramer binds two molecules of protoheme IV. It is a homotetramer involved in tryptophan catabolism. There is a broad specificity towards tryptamine and derivatives including D- and L-tryptophan, 5-hydroxytryptophan and serotonin.


Catalog Number: (10071-482)
Supplier: Prosci
Description: p53 is a nuclear protein which plays an essential role in the regulation of cell cycle specifically in the transition from G0 to G1. It is found in very low levels in normal cells however in a variety of transformed cell lines in high amounts and believed to contribute to transformation and malignancy. The open reading frame of p53 is 393 amino acids long, with the central region (consisting of amino acids from about 100 to 300) containing the DNA-binding domain. This proteolysis-resistant core is flanked by a C-terminal end mediating oligomerization and an N-terminal end containing a strong transcription activation signal. p53 binds as a tetramer to a PBS (p53-Binding Site) and activates the expression of downstream genes that inhibit growth and/or invasion. p53 binds as a tetramer to a p53-binding site (PBS) and to activate the expression of adjacent genes that inhibit growth and/or invasion. Deletion of one or both p53 alleles reduces the expression of tetramers, resulting in decreased expression of the growth inhibitory genes


Catalog Number: (10103-896)
Supplier: Prosci
Description: Casein kinase II is a serine/threonine protein kinase that phosphorylates acidic proteins such as casein. The kinase exists as a tetramer and is composed of an alpha, an alpha-prime, and two beta subunits. The alpha subunits contain the catalytic activity while the beta subunits undergo autophosphorylation. CSNK2A1 represents the alpha subunit.Casein kinase II is a serine/threonine protein kinase that phosphorylates acidic proteins such as casein. The kinase exists as a tetramer and is composed of an alpha, an alpha-prime, and two beta subunits. The alpha subunits contain the catalytic activity while the beta subunits undergo autophosphorylation. The protein encoded by this gene represents the alpha subunit. While this gene is found on chromosome 20, a related transcribed pseudogene is found on chromosome 11. Three transcript variants encoding two different proteins have been found for this gene.


Catalog Number: (AAAL16614-14)
Supplier: Thermo Scientific Chemicals
Description: HFPO tetramer acid fluoride. Grade: 97. Melting Point C. Boiling Point C: 158-161*. C12F24O4. 27639-98-1. CORROSIVE MOISTURE SENSITIVE

Catalog Number: (10363-712)
Supplier: Bioss
Description: Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton, and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. It is a tetramer made up of alpha-beta dimers linked in a head-to-head arrangement. This gene is one member of a family of alpha-spectrin genes. The encoded protein is primarily composed of 22 spectrin repeats which are involved in dimer formation. It forms weaker tetramer interactions than non-erythrocytic alpha spectrin, which may increase the plasma membrane elasticity and deformability of red blood cells. Mutations in this gene result in a variety of hereditary red blood cell disorders, including elliptocytosis type 2, pyropoikilocytosis, and spherocytic hemolytic anemia. [provided by RefSeq, Jul 2008].


Supplier: TCI America
Description: CAS Number: 108-62-3
MDL Number: MFCD00134115
Molecular Formula: C8H16O4
Molecular Weight: 176.21
Purity/Analysis Method: >97.0% (T)
Form: Crystal
Boiling point (°C): 65
Melting point (°C): 246
Flash Point (°C): 50
Storage Temperature: 0-10°C
Catalog Number: (RL100401J04S)
Supplier: Rockland Immunochemical
Description: Eg5 (Also Known As Kinesin-5 And Kif11) Is A Homo-Tetramer Which Cross-Links Anti-Parallel Microtubules In The Mitotic Spindle To Maintain Spindle Bipolarity.


Catalog Number: (76481-614)
Supplier: AAT BIOQUEST INC
Description: This bifunctional biotin-fluorescein conjugate demonstrates better binding and stronger fluorescence than biotin fluorescein.

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Catalog Number: (89367-222)
Supplier: Genetex
Description: C1q is a sub-component of the first complement component C1, which is formed by the interaction of C1q with the tetramer C1s-C1r-C1r-C1s.


Catalog Number: (RL100401J04)
Supplier: Rockland Immunochemical
Description: Eg5 (Also Known As Kinesin-5 And Kif11) Is A Homo-Tetramer Which Cross-Links Anti-Parallel Microtubules In The Mitotic Spindle To Maintain Spindle Bipolarity.


Supplier: Diagnostic Biosystems
Description: Caspase 1 and is expressed as a proenzyme in many tissues. Active Caspase 1 is a tetramer of two subunits p10 and p20 in 2:2 ratio. Overexpression of caspase 1 can induce apoptosis in fibroblast, which can be inhibited by overexpression of Crm A, a protein from pox virus.

Catalog Number: (77436-938)
Supplier: Bioss
Description: Spectrin is an actin binding protein that is a major component of the plasma membrane skeleton. Spectrins function as membrane organizers and stabilizers by forming dimers, tetramers and higher polymers. Spectrin Alpha and spectrin Beta are present in erythrocytes, whereas spectrin Alpha II (also designated fodrin Alpha) and spectrin Beta I (also designated fodrin Beta) are present in other somatic cells. The spectrin tetramers in erythrocytes act as barriers to lateral diffusion, but spectrin dimers seem to lack this function. Spectrin Beta III is highly homologous to both spectrin Beta I and spectrin Beta II. Western blot analysis shows that spectrin Beta III migrates at a higher molecular mass than predicted in the kidney. Spectrin Beta III is highly expressed in brain, kidney, pancreas, and liver, and at lower levels in lung and placenta. Specifically, spectrin Beta III constitutes a major component of the Golgi and vesicular membrane skeletons.


Supplier: Spectrum Chemicals
Description: Catalase, Lyophilized, a tetramer of four polypeptide chains, is used in the food industry to remove hydrogen peroxide from milk in order to make cheese. Ungraded products supplied by Spectrum are indicative of a grade suitable for general industrial use or research purposes and typically are not suitable for human consumption or therapeutic use. These materials may or may not have a Certificate of Analysis available.
Catalog Number: (76484-952)
Supplier: AAT BIOQUEST INC
Description: This bifunctional Cy5 biotin conjugate demonstrates excellent avidin binding and strong fluorescence.

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