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Catalog Number: (470005-924)
Supplier: Dwyer Instruments
Description: Simple to Use; Requires No Calibration


Supplier: DWYER INSTRUMENTS / LOVE CONTROL
Description: Easily view flow indicator through clear plastic housing.

CE Compliant

Supplier: DWYER INSTRUMENTS / LOVE CONTROL
Description: Easy-to-read scales.

Catalog Number: (103485-238)
Supplier: Affymetrix, Inc.
Description: This antibody is predicted to react with non-human primate based on 100% sequence homology. This antibody is specific for the ~80 kDa 5-LO phosphorylated at Ser523 in Western blots of rat hippocampal lysates. The enzyme 5-lipoxygenase (5-LO) plays a key role in regulating the production of leukotrienes (LT ) (Funk, 2001). Overproduction of LT contributes to several diseases, most notably chronic inflammatory diseases, including asthma (Drazen et al. , 1994), fibrosis (Wilborn et al. , 1996) and atherosclerosis (Dwyer et al. , 2004). Recent work has demonstrated that the activity of 5-LO is regulated by PKA phosphorylation of serine-523 in 5-LO (Luo et al. , 2004). Under normal conditions, this phosphorylation may be important in limiting inflammation. Abnormal signaling through cAMP and PKA, then, could contribute to a variety of diseases, including those characterized by chronic inflammation. The phospho-pecific antibody to Ser523 on 5-LO is thus likely to provide a valuable toll for studies of the role of 5-LO regulation in diseases such as asthma, fibrosis and atherosclerosis.

Blocked

Catalog Number: (76009-700)
Supplier: Prosci
Description: ETS transcriptions factors, such as ETS1, regulate numerous genes and are involved in stem cell development, cell senescence and death, and tumorigenesis. The conserved ETS domain within these proteins is a winged helix-turn-helix DNA-binding domain that recognizes the core consensus DNA sequence GGAA/T of target genes (summary by Dwyer et al., 2007 [PubMed 17986575]).


Catalog Number: (103417-530)
Supplier: Affymetrix, Inc.
Description: This Antibody targets ETS2 in immunofluorescence, immunoprecipitation, immunocytochemistry, and Western blot applications and shows reactivity with Human samples. The immunogen is recombinant fragment corresponding to a region within amino acids 1 and 287 of Human ETS2. ETS transcriptions factors, such as ETS2, regulate numerous genes and are involved in stem cell development, cell senescence and death, and tumorigenesis. The conserved ETS domain within these proteins is a winged helix-turn-helix DNA-binding domain that recognizes the core consensus DNA sequence GGAA/T of target genes (Dwyer et al. , 2007 [PubMed 17986575]).

Blocked

Catalog Number: (10111-536)
Supplier: Prosci
Description: ETS2 contains an ETS DNA-binding domain and belongs to the ETS family. ETS2 is a target of protein kinase C and upregulates GM-CSF. Ets2 and its targets play essential roles in endothelial cell function. Coexpression of Ets-2 and SRC-1 significantly associated with the rate of recurrence and HER expression in breast cancer. Overexpression of ETS2 is associated with human esophageal squamous cell carcinoma. ETS transcriptions factors, such as ETS2, regulate numerous genes and are involved in stem cell development, cell senescence and death, and tumorigenesis. The conserved ETS domain within these proteins is a winged helix-turn-helix DNA-binding domain that recognizes the core consensus DNA sequence GGAA/T of target genes (Dwyer et al., 2007 [PubMed 17986575]).


Catalog Number: (89203-047)
Supplier: VWR International
Description: Recyclable trays feature a built-in angle to prevent separation of thermometer liquid.


Supplier: VWR International
Description: Extend the life and accuracy of your expensive and fragile instruments.

3A Sanitary approval

Catalog Number: (76457-534)
Supplier: VWR International
Description: Wide variety of VWR® student dissection kits that suit educational needs.


Catalog Number: (76457-530)
Supplier: VWR International
Description: Wide variety of VWR® student dissection kits that suit educational needs.


Catalog Number: (76221-324)
Supplier: VWR International
Description: These plates are designed to give optimum results from any instrument which reads from the top of the plate.

Catalog Number: (76644-698)
Supplier: VWR International
Description: The P6 UV/Visible single beam spectrophotometer is an easy to use instrument with advanced performance.


Catalog Number: (76644-700)
Supplier: VWR International
Description: The P9 UV/Visible double-beam spectrophotometer is an easy to use instrument with advanced performance.


Supplier: VWR International
Description: VWR® qPCR Master Mix features a distinctive universal passive reference dye that is compatible with ROX-dependent and ROX-independent qPCR instruments.
Supplier: VWR International
Description: The VWR® Anti-Vibration Table provides stability to aid in optimal performance of precision weighing instruments.

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organization. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at 1-800-932-5000.
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