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Image Unavailable-10295-270

Anti-GADL1 Rabbit Polyclonal Antibody

Catalog Number: (10295-270)
Supplier: Bioss
Description: There are two forms of glutamic acid decarboxylases (GADs) that exist in brain: GAD-65 (also known as GAD2) and GAD-67 (also known as GAD1, GAD or SCP). GAD-65 and GAD-67 are members of the group II decarboxylase family of proteins and are responsible for catalyzing the rate limiting step in the production of GABA (gamma-aminobutyric acid) from L-glutamic acid. Although both GADs are found in brain, GAD-65 localizes to synaptic vesicle membranes in nerve terminals, while GAD-67 is distributed throughout the cell. GAD-67 is responsible for the basal levels of GABA synthesis. In the case of a heightened demand for GABA in neurotransmission, GAD-65 transiently activates to assist in GABA production. As a member of the group II decarboxylase family, GADL1 (Glutamate decarboxylase-like protein 1) is a 521 amino acid protein that utilizes pyridoxal phosphate as a cofactor for its carboxylase activity. There are two isoforms of GADL1 that exist as a result of alternative splicing events.
Product Image-75929-842

Anti-ARMET Rabbit Polyclonal Antibody

Catalog Number: (75929-842)
Supplier: Rockland Immunochemical
Description: MANF, also known as ARMET, was initially identified as a protein containing an arginine-rich region that was highly mutated in a variety of tumors. More recently it was identified as a mesencephalic astrocyte-derived neurotrophic factor with selectivity for dopaminergic neurons, similar to glial cell line-derived neurotrophic factor (GDNF) and CDNF. In rat brain slices, MANF enhanced nigral gamma-aminobutyric acid release. Like GDNF and CDNF, MANF has selective neuroprotective activity for dopaminergic neurons suggesting that it may be indicated for the treatment of Parkinson's disease. Expression of MANF has also been shown to be induced during ER stress, suggesting that it may play a role in protein quality control during ER stress.
Image Unavailable-10270-042

Anti-GABRB2 Rabbit Polyclonal Antibody (Cy5®)

Catalog Number: (10270-042)
Supplier: Bioss
Description: GAD-65 and GAD-67, glutamate decarboxylases, function to catalyze the production of GABA (gamma-aminobutyric acid). In the central nervous system GABA functions as the main inhibitory transmitter by increasing a Cl- conductance that inhibits neuronal firing. GABA has been shown to activate both ionotropic (GABAA) and metabotropic (GABAB) receptors as well as a third class of receptors called GABAC. Both GABAA and GABAC are ligand-gated ion channels, however, they are structurally and functionally distinct.
Image Unavailable-10270-046

Anti-GABRB2 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalog Number: (10270-046)
Supplier: Bioss
Description: GAD-65 and GAD-67, glutamate decarboxylases, function to catalyze the production of GABA (gamma-aminobutyric acid). In the central nervous system GABA functions as the main inhibitory transmitter by increasing a Cl- conductance that inhibits neuronal firing. GABA has been shown to activate both ionotropic (GABAA) and metabotropic (GABAB) receptors as well as a third class of receptors called GABAC. Both GABAA and GABAC are ligand-gated ion channels, however, they are structurally and functionally distinct.
Image Unavailable-10270-040

Anti-GABRB2 Rabbit Polyclonal Antibody (Cy3®)

Catalog Number: (10270-040)
Supplier: Bioss
Description: GAD-65 and GAD-67, glutamate decarboxylases, function to catalyze the production of GABA (gamma-aminobutyric acid). In the central nervous system GABA functions as the main inhibitory transmitter by increasing a Cl- conductance that inhibits neuronal firing. GABA has been shown to activate both ionotropic (GABAA) and metabotropic (GABAB) receptors as well as a third class of receptors called GABAC. Both GABAA and GABAC are ligand-gated ion channels, however, they are structurally and functionally distinct.
Image Unavailable-10801-520

Anti-GABARAP Rabbit Polyclonal Antibody

Catalog Number: (10801-520)
Supplier: Rockland Immunochemical
Description: Gamma-aminobutyric acid (GABA) is the main inhibitory transmitter by increasing a Cl-conductance that inhibits neuronal firing in the central nervous system. It has been shown to activate both ionotropic (GABAA) and metabotropic (GABAB) receptors as well as a third class of receptors called GABAC. GABARAP (GABAA receptor-associated protein) links GABAA receptors to the cytoskeleton and may play a role in intracellular transport of GABAA receptors and its interaction with the cytoskeleton. GABARAP belongs to the MAP1 or ATG8 like family and recent studies show that MAPK15/ERK8 is acting through interaction with ATG8 family proteins to regulate autophagy.
Image Unavailable-10295-178

Anti-GABRP Rabbit Polyclonal Antibody (Cy7®)

Catalog Number: (10295-178)
Supplier: Bioss
Description: GAD-65 and GAD-67, glutamate decarboxylases function to catalyze the production of GABA (Gamma-aminobutyric acid). In the central nervous system GABA functions as the main inhibitory transmitter by increasing a Cl-conductance that inhibits neuronal firing. GABA has been shown to activate both ionotropic (GABAA) and metabotropic (GABAB) receptors as well as a third class of receptors called GABAC. Both GABAA and GABAC are ligand-gated ion channels, however, they are structurally and functionally distinct.
Product Image-76075-998

Anti-GABRA2 Rabbit Polyclonal Antibody

Catalog Number: (76075-998)
Supplier: Prosci
Description: For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:10~50 For FACS starting dilution is: 1:10~50
Image Unavailable-89262-656

Anti-GABRD Mouse Monoclonal Antibody [clone: S151-3]

Catalog Number: (89262-656)
Supplier: Genetex
Description: Mouse monoclonal antibody [S151-3] to GABA-A-receptor-delta
Image Unavailable-89283-828

Anti-GABBR2 Rabbit Polyclonal Antibody

Catalog Number: (89283-828)
Supplier: Genetex
Description: Rabbit polyclonal antibody to GABAB Receptor (phospho Ser783), R2-Subunit
Image Unavailable-89284-110

Anti-GABRB3 Rabbit Polyclonal Antibody

Catalog Number: (89284-110)
Supplier: Genetex
Description: Rabbit polyclonal antibody to GABAA Receptor ß3
Image Unavailable-F-1235.0005BA

DL-2-Aminopimelic acid

Supplier: Bachem Americas
Description: Sequence: DL-2-Aminoheptanedioic acid
Synonym(s): DL-α-Aminopimelic acid#H-DL-Apm-OH

Image Unavailable-89300-312

Anti-GABRA5 Rabbit Polyclonal Antibody

Catalog Number: (89300-312)
Supplier: Genetex
Description: Rabbit polyclonal antibody to GABA A receptor alpha 5
Image Unavailable-F-1185.0025BA

DL-α-Aminoadipic acid

Supplier: Bachem Americas
Description: Sequence: H-DL-Aad-OH
Synonym(s): DL-α-Aminoadipic acid#(RS)-2-Aminohexanedioic acid#H-DL-Homoglu-OH

Image Unavailable-10414-002

Anti-GABBR1 Rabbit Polyclonal Antibody (Cy7®)

Catalog Number: (10414-002)
Supplier: Bioss
Description: Gamma-aminobutyric acid (GABA) is the main inhibitory neurotransmitter in the mammalian central nervous system. GABA exerts its effects through ionotropic [GABA(A/C)] receptors, to produce fast synaptic inhibition, and metabotropic [GABA(B)] receptors, to produce slow, prolonged inhibitory signals. The GABA(B) receptor consists of a heterodimer of two related 7-transmembrane receptors, GABA(B) receptor 1 and GABA(B) receptor 2. The GABA(B) receptor 1 gene is mapped to chromosome 6p21.3 within the HLA class I region close to the HLA-F gene. Susceptibility loci for multiple sclerosis, epilepsy, and schizophrenia have also been mapped in this region. Alternative splicing of this gene generates multiple transcript variants. [provided by RefSeq, Jun 2009].
Image Unavailable-10414-006

Anti-GABBR1 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (10414-006)
Supplier: Bioss
Description: Gamma-aminobutyric acid (GABA) is the main inhibitory neurotransmitter in the mammalian central nervous system. GABA exerts its effects through ionotropic [GABA(A/C)] receptors, to produce fast synaptic inhibition, and metabotropic [GABA(B)] receptors, to produce slow, prolonged inhibitory signals. The GABA(B) receptor consists of a heterodimer of two related 7-transmembrane receptors, GABA(B) receptor 1 and GABA(B) receptor 2. The GABA(B) receptor 1 gene is mapped to chromosome 6p21.3 within the HLA class I region close to the HLA-F gene. Susceptibility loci for multiple sclerosis, epilepsy, and schizophrenia have also been mapped in this region. Alternative splicing of this gene generates multiple transcript variants. [provided by RefSeq, Jun 2009].
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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