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Image Unavailable-10241-734

Anti-GAD2 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalog Number: (10241-734)
Supplier: Bioss
Description: This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Oct 2008]
Image Unavailable-10270-428

Anti-GABRQ Rabbit Polyclonal Antibody (Cy3®)

Catalog Number: (10270-428)
Supplier: Bioss
Description: Gamma-aminobutyric acid type A (GABAA) receptors mediate inhibitory neurotransmission in the mammalian central nervous system. The receptor exists as a pentameric ion channel composed by heteromeric combinations of alpha, beta, gamma, delta, epsilon, theta, or pi subunits. Only specific subunit combinations produce viable receptors, while others never translocate to the cell surface from the ER where they are synthesized, and subsequently degraded. The theta subunit forms a receptor in combination with alpha3 subunits in monoaminergic cell groups. These receptors, found especially in the septum, preoptic areas, hypothalamic nuclei, amygdala and thalamus, likely have unique pharmacological properties linked to their expression in this particular cell type and not cholinergic cell groups, and may play a role in opiate withdrawl symptoms.
Product Image-10748-766

Anti-ALDH5A1 Rabbit Polyclonal Antibody

Catalog Number: (10748-766)
Supplier: Prosci
Description: Aldh5A1 Antibody: Aldh5A1 is a member of the aldehyde dehydrogenase superfamily, a group of NAD(P)(+)-dependent enzymes that catalyze the oxidation of a wide spectrum of aliphatic and aromatic aldehydes. Aldehyde dehydrogenase enzymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. Aldh5A1 is a mitochondrial NAD(+)-dependent succinic semialdehyde dehydrogenase. A deficiency of this enzyme, known as 4-hydroxybutyricaciduria, results in a disorder of the neurotransmitter 4-aminobutyric acid (GABA). Symptoms usually include static encephalopathy, associated with developmental delays, hypotonia, ataxia, speech defects, and seizures. At least two isoforms of Aldh5A1 are known to exist.
Image Unavailable-89271-060

Anti-GABRR1 Rabbit Polyclonal Antibody

Catalog Number: (89271-060)
Supplier: Genetex
Description: Rabbit polyclonal antibody to GABRR1 (N-terminal)
Image Unavailable-89264-826

Anti-GABBR1 Rabbit Polyclonal Antibody

Catalog Number: (89264-826)
Supplier: Genetex
Description: Rabbit polyclonal to GABA B receptor 1
Image Unavailable-89366-240

Anti-GABRA2 Rabbit Polyclonal Antibody

Catalog Number: (89366-240)
Supplier: Genetex
Description: Rabbit Polyclonal Antibody to GABRA2
Image Unavailable-10241-732

Anti-GAD2 Rabbit Polyclonal Antibody (Cy7®)

Catalog Number: (10241-732)
Supplier: Bioss
Description: This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Oct 2008]
Image Unavailable-89284-116

Anti-GABRA6 Rabbit Polyclonal Antibody

Catalog Number: (89284-116)
Supplier: Genetex
Description: Rabbit polyclonal antibody to GABAA Receptor a 6
Product Image-10752-190

Anti-GABARAPL2 Rabbit Polyclonal Antibody

Catalog Number: (10752-190)
Supplier: Prosci
Description: Gamma-aminobutyric acid (GABA) is the main inhibitory transmitter by increasing a Cl-conductance that inhibits neuronal firing in the central nervous system. It has been shown to activate both ionotropic (GABAA) and metabotropic (GABAB) receptors as well as a third class of receptors called GABAC. GABARAPL2 (GABAA receptor-associated protein-like 2), also known as GATE16, was initially identified as a membrane transport modulator and is a mammalian ortholog to the autophagy protein ATG8. It is thought that GABARAPL2 and other members of the ATG8 family act as scaffolds for assembly of the Unc-51 like kinase (ULK) complex in the formation of autophagosomes.
Image Unavailable-89294-674

Anti-GABRB3 Goat Polyclonal Antibody

Catalog Number: (89294-674)
Supplier: Genetex
Description: Goat polyclonal antibody to GABRB3
Image Unavailable-10295-174

Anti-GABRP Rabbit Polyclonal Antibody (Cy3®)

Catalog Number: (10295-174)
Supplier: Bioss
Description: GAD-65 and GAD-67, glutamate decarboxylases function to catalyze the production of GABA (Gamma-aminobutyric acid). In the central nervous system GABA functions as the main inhibitory transmitter by increasing a Cl-conductance that inhibits neuronal firing. GABA has been shown to activate both ionotropic (GABAA) and metabotropic (GABAB) receptors as well as a third class of receptors called GABAC. Both GABAA and GABAC are ligand-gated ion channels, however, they are structurally and functionally distinct.
Image Unavailable-10284-558

Anti-GABRP Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (10284-558)
Supplier: Bioss
Description: GAD-65 and GAD-67, glutamate decarboxylases function to catalyze the production of GABA (Gamma-aminobutyric acid). In the central nervous system GABA functions as the main inhibitory transmitter by increasing a Cl-conductance that inhibits neuronal firing. GABA has been shown to activate both ionotropic (GABAA) and metabotropic (GABAB) receptors as well as a third class of receptors called GABAC. Both GABAA and GABAC are ligand-gated ion channels, however, they are structurally and functionally distinct.
Image Unavailable-10270-048

Anti-GABRB2 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (10270-048)
Supplier: Bioss
Description: GAD-65 and GAD-67, glutamate decarboxylases, function to catalyze the production of GABA (gamma-aminobutyric acid). In the central nervous system GABA functions as the main inhibitory transmitter by increasing a Cl- conductance that inhibits neuronal firing. GABA has been shown to activate both ionotropic (GABAA) and metabotropic (GABAB) receptors as well as a third class of receptors called GABAC. Both GABAA and GABAC are ligand-gated ion channels, however, they are structurally and functionally distinct.
Image Unavailable-10272-476

Anti-GABRR2 Rabbit Polyclonal Antibody (Cy3®)

Catalog Number: (10272-476)
Supplier: Bioss
Description: Gamma-aminobutyric acid (GABA) receptors are pentameric membrane proteins that operate GABA-gated chloride channels and inhibit neurotransmission in the central nervous system. The rho receptor subunits do not exhibit sensitivity to typical GABA receptor modulators such as bicuculline, hexobarbital, and diazepam. While the rho 1 subunit localizes specifically to the retina, rho 2 expresses in all regions of the brain, though levels were still highest in the retina, implying a role for both subunits in visual pathways.
Image Unavailable-10295-176

Anti-GABRP Rabbit Polyclonal Antibody (Cy5®)

Catalog Number: (10295-176)
Supplier: Bioss
Description: GAD-65 and GAD-67, glutamate decarboxylases function to catalyze the production of GABA (Gamma-aminobutyric acid). In the central nervous system GABA functions as the main inhibitory transmitter by increasing a Cl-conductance that inhibits neuronal firing. GABA has been shown to activate both ionotropic (GABAA) and metabotropic (GABAB) receptors as well as a third class of receptors called GABAC. Both GABAA and GABAC are ligand-gated ion channels, however, they are structurally and functionally distinct.
Image Unavailable-89286-642

Anti-GABRP Rabbit Polyclonal Antibody

Catalog Number: (89286-642)
Supplier: Genetex
Description: Rabbit Polyclonal Antibody to GABRP
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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