You Searched For: Cycloheximide


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Supplier: Thermo Scientific Chemicals
Description: A frequently used lab reagent that inhibits fungal growth by targeting protein synthesis.
Supplier: MP Biomedicals
Description: Applications
Cycloheximide is used in protein synthesis in apoptosis. It is also used in plant research to study disease resistance and as an ethylene stimulant, useful in studies involving fruit and leaf production.
Product Description
Cycloheximide is an antibiotic which is very active against many molds, yeasts, and phytopathogenic fungi. It exhibits somewhat lower activity against bacteria and certain fungi. It inhibits peptide synthesis in eukaryotic organisms but not in prokaryotes. Protein synthesis is blocked by the interaction of Cycloheximide with the translocase enzyme. This interaction prohibits the translocation of messenger RNA on the cytosolic, 80S ribosomes without inhibiting organelle protein synthesis.
Biochem/physiol Actions
Cycloheximide (CHX) is an antibiotic produced by S. griseus. Its main biological activity is translation inhibition in eukaryotes resulting in cell growth arrest and cell death. CHX is widely used for selection of CHX-resistant strains of yeast and fungi, controlled inhibition of protein synthesis for detection of short-lived proteins and super-induction of protein expression, and apoptosis induction or facilitation of apoptosis induction by death receptors.

Catalog Number: (100505-650)
Supplier: R&D Systems
Description: Inhibitor of protein synthesis


Supplier: Thermo Scientific Chemicals
Description: Cycloheximide 95%

Supplier: Enzo Life Sciences
Description: Protein synthesis inhibitor

SDS

Catalog Number: (AAJ66004-XF)
Supplier: Thermo Scientific Chemicals
Description: Cycloheximide solution, 100mg/mL in DMSO, 0.2 micron filtered. Liquid.

Supplier: MP Biomedicals
Description: Cycloheximide is a glutarimide antibiotic derived from a microbial source. Cycloheximide is an antibiotic which is very active against many molds, yeasts, and phytopathogenic fungi. It exhibits somewhat lower activity against bacteria and certain fungi. Control of various molds and fungi in gelatin-based photographic emulsions, photoengraving glues, and other light-sensitive products is suggested.
Cycloheximide is used in plant research to study disease resistance and as an ethylene stimulant, useful in studies involving fruit and leaf production. It is also used in bacteriological media to isolate or count bacteria in the presence of yeast and molds; Used in protein synthesis in apoptosis; Gene expression; Glycogenolysis, gluconeogenesis and ureogenesis in isolated rat hepatocytes; Studies involving steroidogenesis; Used in plant regulation and as a quality control measure by the food and beverage industry.
Cycloheximide (CHX) is an antibiotic produced by S. griseus. Its main biological activity is translation inhibition in eukaryotes resulting in cell growth arrest and cell death. CHX is widely used for selection of CHX-resistant strains of yeast and fungi, controlled inhibition of protein synthesis for detection of short-lived proteins and super-induction of protein expression, and apoptosis induction or facilitation of apoptosis induction by death receptors. Cycloheximide inhibits peptide synthesis in eukaryotic organisms but not in prokaryotes. Protein synthesis is blocked by the interaction of Cycloheximide with the translocase enzyme. This interaction prohibits the translocation of messenger RNA on the cytosolic, 80S ribosomes without inhibiting organelle protein synthesis. Cycloheximide is also known to induce FAS/FAS Ligand apoptosis, and triggers apoptosis in HL-60 cells, T-cell hybridomas, Burkitt's lymphoma cells in addition to a variety of other cell types. Cycloheximide will also delay or inhibit apoptosis induced by other agents.
Catalog Number: (82021-600)
Supplier: G-Biosciences
Description: Apoptosis is commonly defined as programmed mechanism of cell death and is a highly regulated process that can be initiated by a variety of internal and external stimuli (inducers).


Catalog Number: (AAJ66901-03)
Supplier: Thermo Scientific Chemicals
Description: Powder

Catalog Number: (75813-970)
Supplier: Hardy Diagnostics
Description: SabHI Agar with Blood, Chloramphenicol and Cycloheximide is used for the selective isolation of pathogenic fungi.

Product available on GSA Advantage®


Catalog Number: (77691-587)
Supplier: LGC STANDARDS
Description: Cycloheximide 100 µg/mL in Acetonitrile, Dr. Ehrenstorfer, LGC Standards

New Product


Catalog Number: (90004-936)
Supplier: BD
Description: This medium is used for the cultivation of dermatophytes and other pathogenic and nonpathogenic fungi from clinical and non-clinical specimens.

Catalog Number: (10146-968)
Supplier: Hardy Diagnostics
Description: for the isolation and cultivation of microorganisms while inhibiting Saprophytic fungal organisms.

Catalog Number: (75845-728)
Supplier: Hardy Diagnostics
Description: Buffered Charcoal Yeast Extract (BCYE) selective agar with Cephalothin, Colistin, Vancomycin, and Cycloheximide antibiotics for the selective isolation and cultivation of <i>Legionella</i> from environmental and clinical specimens.

Catalog Number: (90008-410)
Supplier: BD
Description: Brain heart infusion agar with chloramphenicol, cycloheximide and sheep blood is a selective medium used for the isolation of pathogenic fungi from specimens heavily contaminated with bacteria and saprophytic fungi.

Catalog Number: (82021-608)
Supplier: G-Biosciences
Description: Apoptosis inducers are used for induction of apoptosis in cultured cells. The selection of apoptosis inducers include actinomycin D, camptothecin, cycloheximide, dexamethasone, doxorubicin and etoposide.


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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