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Image Unavailable-76098-624

Anti-DcR1 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalog Number: (76098-624)
Supplier: Bioss
Description: Receptor for the cytotoxic ligand TRAIL. Lacks a cytoplasmic death domain and hence is not capable of inducing apoptosis. May protect cells against TRAIL mediated apoptosis by competing with TRAIL-R1 and R2 for binding to the ligand.
Image Unavailable-102515-808

Jasplakinolide ≥98% (by HPLC), high purity

Supplier: Adipogen
Description: Cell permeable, non-fluorescent F-actin probe. Potent inducer of actin polymerization and stabilization. Competes with phallotoxins for actin binding. Antifungal and antiparasitic compound. Antiproliferative and anticancer compound. Apoptosis enhancer/inducer. Tool used for autophagy/phagocytosis research.

Image Unavailable-H-3134.0500BA

Mouse;Rabbit;Rat (Cys¹⁸)-Atrial Natriuretic Factor (4-18) amide

Supplier: Bachem Americas
Description: C-ANF 4-23 binds with high affinity to approximately 99% of ANF receptors in the isolated perfused rat kidney. It competes effectively with biologically active atrial peptides for binding sites but is devoid of agonist or antagonist action on the generation of cGMP in vascular smooth muscle and endothelial cells in culture.

Image Unavailable-102516-072

BIX 01294 ≥98%

Supplier: Adipogen
Description: Selective and cell permeable G9a histone-lysine methyltransferase (HMTase) inhibitor. Does not compete with cofactor S-adenosylmethionine. Pluripotent stem cell inducer.

Small Business Enterprise

Product Image-104013-362

igNext™ NGS DNA Library Preperation Kit, Intact Genomics

Supplier: INTACT GENOMICS, INC MS
Description: The igNext™ NGS DNA library preperation kit includes high-quality buffers and enzymes needed to make DNA fragment libraries for whole-genome sequencing on the Illumina platform. This kit facilitates consistent and proven performance for various types of samples.

Image Unavailable-76634-560

Anti-P16 Mouse Antibody [clone: JC2]

Catalog Number: (76634-560)
Supplier: Diagnostic Biosystems
Description: P16 is a mitotic inhibitor protein. It competes with D-type cyclins to bind to cdk4 and cdk6. It acts as tumor suppressor and inhibits the progression of cells through the G1 phase of the cell cycle.
Image Unavailable-102514-314

Anti-TRAIL-R4 Mouse Monoclonal Antibody [clone: HS402]

Catalog Number: (102514-314)
Supplier: Adipogen
Description: TRAIL-R4 is a receptor for the cytotoxic ligand TRAIL. Contains a truncated death domain and hence is not capable of inducing apoptosis. Protects cells against TRAIL mediated apoptosis by competing with TRAIL-R1 and R2 for binding to the ligand.
Product Image-10102-248

Anti-MAX Rabbit Polyclonal Antibody

Catalog Number: (10102-248)
Supplier: Prosci
Description: MAX is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with other family members, which include Mad, Mxi1 and Myc. Myc is an oncoprotein implicated in cell proliferation, differentiation and apoptosis. The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation.The protein encoded by this gene is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with other family members, which include Mad, Mxi1 and Myc. Myc is an oncoprotein implicated in cell proliferation, differentiation and apoptosis. The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation. Multiple alternatively spliced transcript variants have been described for this gene but the full length nature for some of them is unknown.The protein encoded by this gene is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with other family members, which include Mad, Mxi1 and Myc. Myc is an oncoprotein implicated in cell proliferation, differentiation and apoptosis. The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation. Multiple alternatively spliced transcript variants have been described for this gene but the full-length nature for some of them is unknown.
Image Unavailable-76098-622

Anti-DcR1 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (76098-622)
Supplier: Bioss
Description: Receptor for the cytotoxic ligand TRAIL. Lacks a cytoplasmic death domain and hence is not capable of inducing apoptosis. May protect cells against TRAIL mediated apoptosis by competing with TRAIL-R1 and R2 for binding to the ligand.
Image Unavailable-102514-322

Anti-TRAIL-R3 Mouse Monoclonal Antibody [clone: TR3.06]

Catalog Number: (102514-322)
Supplier: Adipogen
Description: TRAIL-R3 is a receptor for the cytotoxic ligand TRAIL. It lacks a cytoplasmic death domain and hence is not capable of inducing apoptosis. Protects cells against TRAIL mediated apoptosis by competing with TRAIL-R1 and R2 for binding to the ligand.
Image Unavailable-102514-312

Anti-TRAIL-R3 Mouse Monoclonal Antibody [clone: HS301]

Catalog Number: (102514-312)
Supplier: Adipogen
Description: TRAIL-R3 is a receptor for the cytotoxic ligand TRAIL. It lacks a cytoplasmic death domain and hence is not capable of inducing apoptosis. Protects cells against TRAIL mediated apoptosis by competing with TRAIL-R1 and R2 for binding to the ligand.
Image Unavailable-10459-350

Anti-OGT Rabbit Polyclonal Antibody

Catalog Number: (10459-350)
Supplier: Bioss
Description: Addition of nucleotide-activated sugars directly onto the polypeptide through O-glycosidic linkage with the hydroxyl of serine or threonine. Mediates the O-glycosylation of MLL5 and HCFC1. Promotes proteolytic maturation of HCFC1. Since both phosphorylation and glycosylation compete for similar serine or threonine residues, the two processes may compete for sites, or they may alter the substrate specificity of nearby sites by steric or electrostatic effects. O-GlcNAc transferase has been purified from rat liver. It exists as a heterotrimeric complex with two subunits of the same molecular mass and one shorter subunit. Both polypeptides are related; the short subunit band is either a proteolytic product of the polypeptide or the product of an alternative translation start site. O-GlcNAc transferase is expressed as multiple transcripts that are present in different amounts in various human tissues, with the highest levels of expression in pancreas. Immunofluorescence of human cells expressing rat O-GlcNAc transferase indicated that it is present in both the nucleus and cytosol. HeLa cells expressing O-GlcNAc transferase do not survive well during prolonged incubations, suggesting that this protein may be toxic to the cells.
Image Unavailable-95056-464

Iodoacetamide, Proteomics Grade

Catalog Number: (95056-464)
Supplier: Cytiva
Description: Used for the efficient alkylation of thiols while minimizing oxidation of competing thiol pairs in protein samples.

SDS Certificates Product available on GSA Advantage®


Image Unavailable-102516-200

BIX 01294 trihydrochloride ≥98%

Supplier: Adipogen
Description: Selective and cell permeable G9a histone-lysine methyltransferase (HMTase) inhibitor. Does not compete with cofactor S-adenosylmethionine. Pluripotent stem cell inducer.

Small Business Enterprise

Product Image-76011-506

Anti-SH2D4A Rabbit Polyclonal Antibody

Catalog Number: (76011-506)
Supplier: Prosci
Description: SH2D4A inhibits estrogen-induced cell proliferation by competing with PLCG for binding to ESR1, blocking the effect of estrogen on PLCG and repressing estrogen-induced proliferation. May play a role in T-cell development and function.
Product Image-10105-262

Anti-KAT2B Rabbit Polyclonal Antibody

Catalog Number: (10105-262)
Supplier: Prosci
Description: CBP and p300 are large nuclear proteins that bind to many sequence-specific factors involved in cell growth and/or differentiation, including c-jun and the adenoviral oncoprotein E1A. PCAF associates with p300/CBP. It has in vitro and in vivo binding activity with CBP and p300, and competes with E1A for binding sites in p300/CBP. It has histone acetyl transferase activity with core histones and nucleosome core particles, indicating that this protein plays a direct role in transcriptional regulation.CBP and p300 are large nuclear proteins that bind to many sequence-specific factors involved in cell growth and/or differentiation, including c-jun and the adenoviral oncoprotein E1A. The protein encoded by this gene associates with p300/CBP. It has in vitro and in vivo binding activity with CBP and p300, and competes with E1A for binding sites in p300/CBP. It has histone acetyl transferase activity with core histones and nucleosome core particles, indicating that this protein plays a direct role in transcriptional regulation.
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at 1-800-932-5000.
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