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Product Image-89351-314

Anti-CD15 Mouse Monoclonal Antibody [clone: MMA]

Catalog Number: (89351-314)
Supplier: Genetex
Description: The CD15 antigen is expressed on approximately 90% human circulating granulocytes (membranes and granules), 30 to 60% of circulating monocytes and is absent from normal lymphocytes. CD15 antigen is also expressed on Reed Sternberg cells of Hodgkin's disease, on T cell lymphomas including mycosis fungoides and on some leukemias. Outside the hematopoietic system, CD15 expression is described in certain normal and neoplastic epithelial cells and in astrocytes. CD15 antibodies recognize the tri saccharide 3 fucosyllactosamine (3Fl) which is present in lacto N fucopentaose III and in the blood group antigen X hapten. At least 5 major CD15 antigens (105, 135, 165, 185, 220 kDa) are present on the surface membranes of polymorphonuclear cells. The hapten occurs also in glycolipids. CD15 plays a role in mediating phagocytosis, bactericidal activity and chemotaxis.
Product Image-76287-968

Vaplock™ Nalgene® Waste Caps and Waste Kits, 83B, Cole-Parmer

Supplier: Antyila Scientific
Description: The Vaplock™ closed system design reduces chemical evaporation and exposure to hazardous vapors.

Product Image-76287-826

Vaplock™ Nalgene® Waste Caps and Waste Kits, 53B, Cole-Parmer

Supplier: Antyila Scientific
Description: The Vaplock™ closed system design reduces chemical evaporation and exposure to hazardous vapors.

Product Image-76287-446

Vaplock™ 61 mm Waste Caps and Waste Kits, Cole-Parmer

Supplier: Antyila Scientific
Description: The Vaplock™ closed system design reduces chemical evaporation and exposure to hazardous vapors.

Product Image-PAV6273

ALK6 Kinase Enzyme System, Promega

Supplier: Promega Corporation
Description: ALK6 (also known as BMPR1B) is a member of the transmembrane serine/threonine kinase that is the member of the bone morphogenetic protein (BMP) receptor, which is closely related to the activin receptors, ACVR1 and ACVR2.

Product Image-76287-552

Vaplock™ GL 38 Waste Caps and Waste Kits, Cole-Parmer

Supplier: Antyila Scientific
Description: Vaplock™ closed system design reduces chemical evaporation and exposure to hazardous vapors.

Image Unavailable-10263-964

Anti-CCR4 Rabbit Polyclonal Antibody (Cy5®)

Catalog Number: (10263-964)
Supplier: Bioss
Description: High affinity receptor for the C-C type chemokines CCL17/TARC and CCL22/MDC. The activity of this receptor is mediated by G(i) proteins which activate a phosphatidylinositol-calcium second messenger system. Can function as a chemoattractant homing receptor on circulating memory lymphocytes and as a coreceptor for some primary HIV-2 isolates. In the CNS, could mediate hippocampal-neuron survival.
Product Image-75846-410

Forced Air Fine Oven, Yamato

Supplier: Yamato Scientific
Description: This oven has high-accuracy temperature control and a manual exhaust damper.

Product Image-76278-838

FreeZone® Triad® Benchtop Freeze Dryers, Labconco®

Supplier: Labconco
Description: FreeZone® Triad® Benchtop Freeze Dryers are designed for multiple types of lyophilization: flask, bulk and stoppering vials. With the ability to freeze dry samples in so many different forms, the Triad’s versatility and compact design make it perfect for busy labs. Now with Lyo-Works™ OS the Triad is smarter than ever, making freeze drying even challenging samples easy.

Irregular Voltage

Product Image-76287-554

Vaplock™ Nalgene® Waste Caps and Waste Kits, 38-430, Cole-Parmer

Supplier: Antyila Scientific
Description: The Vaplock™ closed system design reduces chemical evaporation and exposure to hazardous vapors.

Product Image-76287-870

Vaplock™ Panel Mount Waste Caps and Waste Kits, Cole-Parmer

Supplier: Antyila Scientific
Description: The Vaplock™ closed system design reduces chemical evaporation and exposure to hazardous vapors.

Product Image-10467-584

Anti-Renalase Rabbit Polyclonal Antibody

Catalog Number: (10467-584)
Supplier: Bioss
Description: Catalyzes the oxidation of the less abundant alpha-NAD(P)H isoform to form beta-NAD(P)(+). The enzyme hormone is secreted by the kidney, and circulates in blood and modulates cardiac function and systemic blood pressure. Lowers blood pressure in vivo by decreasing cardiac contractility and heart rate and preventing a compensatory increase in peripheral vascular tone, suggesting a causal link to the increased plasma catecholamine and heightened cardiovascular risk. High concentrations of catecholamines activate plasma renalase and promotes its secretion and synthesis.
Product Image-76287-844

Vaplock™ 63 mm Waste Caps (Rieke/Nowpak) and Waste Kits, Cole-Parmer

Supplier: Antyila Scientific
Description: Vaplock™ closed system design reduces chemical evaporation and exposure to hazardous vapors.

Product Image-102830-674

Human Recombinant Serglycin (from E. coli)

Catalog Number: (102830-674)
Supplier: BioVendor
Description: Serglycin was found to be among the most abundantly expressed proteins in adipocytes of epicardial adipose tissue in patients with coronary artery disease (CAD). It was demonstrated that TNFα induces expression and secretion of serglycin in adipocytes. Circulating serglycin might also participate in the mechanism of systemic vascular insult and atheromatous change. Serglycin is a dominant intracellular proteoglycan expressed by immune cells, where it interacts with numerous inflammatory mediators, such as proteases, chemokines, cytokines, and growth factors. Serglycin is implicated in their storage into the granules and their protection since they are secreted as complexes and delivered to their targets after secretion.
Image Unavailable-75791-082

Mouse Recombinant MIF (from E. coli)

Catalog Number: (75791-082)
Supplier: Prosci
Description: Macrophage migration inhibitory factor(MIF) is a secreted protein and belongs to the MIF family. MIF is an important regulator of innate immunity. The circulating MIF binds to CD74 on other immune cells to trigger an acute immune response. Hence MIF is classified as an inflammatory cytokine. Furthermore glucocorticoids also stimulate white blood cells to release MIF and hence MIF partially counter acts the inhibitory effects that glucocorticoids have on the immune system. Finally trauma activates the anterior pituitary gland to release MIF.
Product Image-89511-302

Corning® Polycarbonate Erlenmeyer Flask, Male Luer Lock, Corning

Supplier: Corning
Description: Corning closed system Erlenmeyer flasks will both reduce contamination risk and enhance the productivity of your shaker culture operations when adding or removing medium and cells.

Certificates Environmentally Preferable Product available on GSA Advantage®

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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