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Supplier: Avantor
Description: Battery-powered electrophoresis.

Catalog Number: (470039-968)
Supplier: Edvotek
Description: Simulate Genetic Diagnosis of Sickle Cell Anemia


Catalog Number: (470144-216)
Supplier: United Scientific Supplies
Description: This large plasmid model teaches students the basics of recombinant DNA technology.


Catalog Number: (470101-432)
Supplier: Edvotek
Description: Biotechnology-Based Diagnostic Tests


Catalog Number: (470007-838)
Supplier: Kemtec
Description: Test Properties of Enzymes in Household Products


Catalog Number: (470213-358)
Supplier: United Scientific Supplies
Description: Students solve the case with ink chromatography and STEM.


Catalog Number: (470007-374)
Supplier: Edvotek
Description: Restriction enzymes are endonucleases that recognize and cut double-stranded DNA within or near defined base sequences. They are essential tools for biotechnology.


Catalog Number: (470121-716)
Supplier: Edvotek
Description: For AP Biology Classes


Catalog Number: (470121-714)
Supplier: Edvotek
Description: The Principles and Practice of Agarose Gel Electrophoresis Kit demonstrates how electrophoresis separates molecules on the basis of size and charge.


Catalog Number: (470189-534)
Supplier: Edvotek
Description: Students perform thin-layer chromatographic separation of carotene, xanthophyll, and chlorophylls.


Catalog Number: (10101-058)
Supplier: Prosci
Description: N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate receptors. NMDA channel has been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of the key receptor subunit NMDAR1 (GRIN1) and 1 or more of the 4 NMDAR2 subunits: NMDAR2A (GRIN2A), NMDAR2B (GRIN2B), NMDAR2C (GRIN2C), and NMDAR2D (GRIN2D).


Catalog Number: (10100-594)
Supplier: Prosci
Description: PPP1CA is one of the three catalytic subunits of protein phosphatase 1 (PP1). PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription. Increased PP1 activity has been observed in the end stage of heart failure. Studies in both human and mice suggest that PP1 is an important regulator of cardiac function. Mouse studies also suggest that PP1 functions as a suppressor of learning and memory.The protein encoded by this gene is one of the three catalytic subunits of protein phosphatase 1 (PP1). PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription. Increased PP1 activity has been observed in the end stage of heart failure. Studies in both human and mice suggest that PP1 is an important regulator of cardiac function. Mouse studies also suggest that PP1 functions as a suppressor of learning and memory. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene.


Catalog Number: (103458-810)
Supplier: Affymetrix, Inc.
Description: This antibody recognizes CREB protein phosphorylated at serine 133 and ATF1 phosphorylated at serine 63. The antibody was purified from serum-free cell culture supernatant by subsequent thiophilic adsorption and size exclusion chromatography. Aliquot and freeze in liquid nitrogen. Antibody can be stored frozen at -80ºC for up to 1 year. Thaw aliquots at 37ºC; thawed aliquots may be stored at 4ºC for up to 3 months. Avoid repeated freeze/thaw cycles. This antibody was originally validated as part of a Thermo Scientific Cellomics High Content Screening Kit. The antibody sold separately may have slightly different performance and may need to be further optimized for the best results. Cyclic AMP response element binding protein (CREB) is a basic/leucine zipper transcription factor that binds the cyclic AMP response element (CRE) and activates transcription in response to a variety of extracellular signals including neurotransmitters, hormones, membrane depolarization, and growth and neurotrophic factors. Activation of CREB is dependent upon the phosphorylation of serine 133. Phosphorylation occurs via p44/42 MAP kinase and p90RSK and also via p38 MAP kinase and MSK1. Although CREB will bind DNA independent of its phosphorylation state, only the phosphorylated form is competent as a transcription factor. CREB binding protein (CBP), a transcriptional coactivator that directly interacts with CREB, binds to CREB in the region of serine 133. CREB appears to play an important role in learning and memory.

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Catalog Number: (470137-618)
Supplier: VWR International
Description: Hands-On Learning


Catalog Number: (470120-700)
Supplier: VWR International
Description: Detect the Presence of Static Electricity


Catalog Number: (470121-102)
Supplier: VWR International
Description: For class model building.


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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