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Supplier: Biotium

Description: Fibronectin Monoclonal antibody, Clone: 2755-8, Host: Mouse, Species reactivity: Mouse, Pig, Rat, Human, Isotype: IgG1, kappa, Conjugate: purified, Immunogen: T-cell lymphoma biopsy, Synonyms: FN1, FNZ, GFND, GFND2, Application: IF, IHC, Size: 100uL

Supplier: Biotium

Description: Cytokeratin 8 (CK8) belongs to the type II (or B or basic) subfamily of high molecular weight cytokeratins and exists in combination with cytokeratin 18 (CK18). CK8 is primarily found in the non-squamous epithelia and is present in majority of adenocarcinomas and ductal carcinomas. It is absent in squamous cell carcinomas. Hepatocellular carcinomas are defined by the use of antibodies that recognize only cytokeratin 8 and 18. CK8 exists on several types of normal and neoplastic epithelia, including many ductal and glandular epithelia such as colon, stomach, small intestine, trachea, and esophagus as well as in transitional epithelium. Anti-CK8 does not react with skeletal muscle or nerve cells. Epithelioid sarcoma, chordoma, and adamantinoma show strong positivity corresponding to that of simple epithelia (with antibodies against CK8, CK18 and CK19). Reportedly, anti-CK8 is useful for the differentiation of lobular (ring-like, perinuclear) from ductal (peripheral-predominant) carcinoma of the breast.

Supplier: Biotium

Description: Nuclear Membrane, Monoclonal antibody, Clone: NM97, Host: Mouse, Species reactivity: Human, Isotype: IgM, kappa, Conjugate: CF647, Immunogen: Nuclei of myeloid leukemia biopsy cells, Application: Immunofluorescence, Size: 500uL

Supplier: Biotium

Description: TGF-alpha, Monoclonal antibody, Clone: TGFA/1119, Host: Mouse, Species reactivity: Rabbit, Zebrafish, Human, Isotype: IgG1, kappa, Conjugate: CF640R, Immunogen: A 10-amino acid synthetic peptide (aa34-43), Synonyms: EGF-like TGF; ETGF, Application: IF, Size: 100uL

Supplier: Biotium

Description: MUC2, Monoclonal antibody, Clone: MLP/842, Host: Mouse, Species reactivity: Human, Isotype: IgG1, kappa, Conjugate: CF488A, Immunogen: synthetic peptide of 29 amino acids, from MUC2 protein, Synonyms: Mucin-2, Intestinal mucin-2, Application: IF, Size: 100uL

Supplier: Biotium

Description: Eukaryotic histones are basic and water-soluble nuclear proteins. They form hetero-octameric nucleosome particles by wrapping 146 base pairs of DNA in a left-handed super-helical turn sequentially to form chromosomal fiber. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form the octamer; formed of two H2A-H2B dimers and two H3-H4 dimers, forming two nearly symmetrical halves by tertiary structure. Over 80% of nucleosomes contain the linker Histone H1, derived from an intronless gene that interacts with linker DNA between nucleosomes and mediates compaction into higher order chromatin. Histones are subject to posttranslational modification by enzymes primarily on their N-terminal tails, but also in their globular domains. Such modifications include methylation, citrullination, acetylation, phosphorylation, sumoylation, ubiquitination and ADP-ribosylation.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®405S is a blue fluorescent dye (Ex/Em 404/431 nm) with superior brightness compared to other blue dyes; it is also compatible with super-resolution imaging by SIM. Note: Conjugates of blue fluorescent dyes are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Supplier: Biotium

Description: This antibody recognizes actin of skeletal, cardiac, and smooth muscle cells. It is not reactive with other mesenchymal cells except for myoepithelium. Actin can be resolved on the basis of its isoelectric points into three distinctive components: alpha, beta, and gamma in order of increasing isoelectric point. Anti-muscle specific actin recognizes alpha and gamma isotypes of all muscle groups. Non-muscle cells such as vascular endothelial cells and connective tissues are non-reactive. Also, neoplastic cells of non-muscle-derived tissue such as carcinomas, melanomas, and lymphomas are negative.It stains tumors of smooth muscle (leiomyomas and leiomyosarcomas) as well as skeletal muscle (rhabdomyomas and rhabdomyosarcomas).

CF® dyes are Biotium's next-generation fluorescent dyes. CF®405S is a blue fluorescent dye (Ex/Em 404/431 nm) with superior brightness compared to other blue dyes; it is also compatible with super-resolution imaging by SIM. Note: Conjugates of blue fluorescent dyes are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Supplier: Biotium

Description: Tyrosinase, Monoclonal antibody, Clone: T311, Host: Mouse, Species reactivity: Human, Isotype: IgG's, Conjugate: CF647, Immunogen: Recombinant tyrosinase protein (T311); Recombinant human TYR protein, Synonyms: CMM8, LB24-AB, Application: IF, Size: 100uL

Supplier: Biotium

Description: CD37 Monoclonal antibody, Clone: IPO-24, Host: Mouse, Species reactivity: Human, Isotype: IgG2b, kappa, Conjugate: CF568, Immunogen: Spleen cells of a patient with hairy cell leukemia, Synonyms: GP52 40, Tspan-26, TSPAN26, Application: IF, FC, Size: 100uL

Supplier: Biotium

Description: CD45 / LCA Monoclonal antibody, Clone: 136-4B5, Host: Mouse, Species reactivity: Human, Isotype: IgG1, kappa, Conjugate: purified, Immunogen: Stimulated human leukocytes, Synonyms: B220, CD45R, Application: IF, IHC, FC, Size: 100uL

Catalog Number: (89139-598)

Supplier: Biotium

Description: The fluorescence of NBD is highly dependent on the environment; it is virtually nonfluorescent in water but becomes strongly green fluorescent in hydrophobic media. NBD-ethylenediamine can be readily coupled to activated carboxy groups or sulfonyl chlorides.

Supplier: Biotium

Description: PGP9.5 (UCHL-1), Monoclonal antibody, Clone: 31A3, Host: Mouse, Species reactivity: Zebrafish, Pig, Dog, Cow, Sheep, Rat, Human, Guinea Pig, Rabbit, Isotype: IgG2a, kappa, Conjugate: biotin, Immunogen: Native UchL1 (PGP9.5) protein from brain, Application: IF, Size: 100uL

Supplier: Biotium

Description: This antibody recognizes a single protein of 33-34 kDa, identified as the prostate specific antigen (PSA). This MAb is highly specific to PSA and stains prostatic secretory and ductal epithelium in both normal and neoplastic tissues. PSA is a chymotrypsin-like serine protease (kallikrein family) exclusively produced by the prostate epithelium, and abundant in seminal fluid. PSA can be detected in the sera of patients with prostatic carcinoma. It is predominantly complexed to a liver-derived serine protease inhibitor, alpha-1-antichymotrypsin (ACT). A higher proportion of serum PSA is complexed to ACT in prostate cancer than in benign prostate hyperplasia. This MAb makes an excellent pair with MAb 1A7G6B6 for PSA tests.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®594 is a deep red fluorescent dye (Ex/Em 593/614 nm). It yields the brightest conjugates among spectrally similar dyes, and has excellent photostability.

Supplier: Biotium

Description: CD74 Monoclonal antibody, Clone: LN-2 + CLIP/813, Host: Mouse, Species reactivity: Human, Isotype: IgG's, Conjugate: biotin, Immunogen: SU-DHL-4 lymphoma cells ; Recombinant full-length human CD74 protein, Application: IF, IHC, FC, Size: 100uL

Supplier: Biotium

Description: PAX6, Monoclonal antibody, Clone: PAX6/1166, Host: Mouse, Species reactivity: Human, Isotype: IgG2a, kappa, Conjugate: CF405S, Immunogen: Recombinant fragment (N-terminus; aa 1-300) of human PAX6 protein, Synonyms: AN2; Aniridia type II protein, Application: IF, Size: 500uL

Supplier: Biotium

Description: Human Nuclear Antigen, Monoclonal antibody, Clone: 235-1, Host: Mouse, Species reactivity: Human, Non-human primates, Isotype: IgG1, kappa, Conjugate: purified, Immunogen: Nuclei of human myeloid leukemia biopsy cells, Synonyms: HNA, Application: IF, Size: 500uL