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Anti-ABCA7 Rabbit Polyclonal Antibody (Cy7®)

Catalog Number: (10250-230)
Supplier: Bioss
Description: ATP-binding cassette (ABC) transporters are an evolutionarily conserved family of widely-expressed proteins that use ATP hydrolysis to catalyze the transport of various molecules across extracellular and intracellular membranes. Eukaryotic ABC transporters are largely responsible for trafficking hydrophobic compounds either within the cell as part of a metabolic process, outside the cell for transport to other organs, or for secretion from the body. The cholesterol-responsive transporter, ABCA7, maps to human chromosome 19 and mouse chromosome 10 and has been reported as a candidate regulator of ceramide transport in epidermal lipid reorganization. High expression levels of ABCA7 have been reported in myelolymphatic tissues, reticuloendothelial cells, peripheral leukocytes, thymus, spleen and bone marrow. This expression pattern of the two alternatively-spliced isoforms also indicates an involvement in lipid homeostasis in cells of the immune system, though the complete role of ABCA7 is not yet known. Full-length type I ABCA7 has shown plasma membrane localization, while the type II splicing variant has shown expression predominantly in the endoplasmic reticulum.
Image Unavailable-10250-226

Anti-ABCA7 Rabbit Polyclonal Antibody (Cy3®)

Catalog Number: (10250-226)
Supplier: Bioss
Description: ATP-binding cassette (ABC) transporters are an evolutionarily conserved family of widely-expressed proteins that use ATP hydrolysis to catalyze the transport of various molecules across extracellular and intracellular membranes. Eukaryotic ABC transporters are largely responsible for trafficking hydrophobic compounds either within the cell as part of a metabolic process, outside the cell for transport to other organs, or for secretion from the body. The cholesterol-responsive transporter, ABCA7, maps to human chromosome 19 and mouse chromosome 10 and has been reported as a candidate regulator of ceramide transport in epidermal lipid reorganization. High expression levels of ABCA7 have been reported in myelolymphatic tissues, reticuloendothelial cells, peripheral leukocytes, thymus, spleen and bone marrow. This expression pattern of the two alternatively-spliced isoforms also indicates an involvement in lipid homeostasis in cells of the immune system, though the complete role of ABCA7 is not yet known. Full-length type I ABCA7 has shown plasma membrane localization, while the type II splicing variant has shown expression predominantly in the endoplasmic reticulum.
Image Unavailable-10250-228

Anti-ABCA7 Rabbit Polyclonal Antibody (Cy5®)

Catalog Number: (10250-228)
Supplier: Bioss
Description: ATP-binding cassette (ABC) transporters are an evolutionarily conserved family of widely-expressed proteins that use ATP hydrolysis to catalyze the transport of various molecules across extracellular and intracellular membranes. Eukaryotic ABC transporters are largely responsible for trafficking hydrophobic compounds either within the cell as part of a metabolic process, outside the cell for transport to other organs, or for secretion from the body. The cholesterol-responsive transporter, ABCA7, maps to human chromosome 19 and mouse chromosome 10 and has been reported as a candidate regulator of ceramide transport in epidermal lipid reorganization. High expression levels of ABCA7 have been reported in myelolymphatic tissues, reticuloendothelial cells, peripheral leukocytes, thymus, spleen and bone marrow. This expression pattern of the two alternatively-spliced isoforms also indicates an involvement in lipid homeostasis in cells of the immune system, though the complete role of ABCA7 is not yet known. Full-length type I ABCA7 has shown plasma membrane localization, while the type II splicing variant has shown expression predominantly in the endoplasmic reticulum.
Product Image-10184-200

Micro-Cut Universal Style Biopsy Punch, OR Grade, Sklar

Supplier: Sklar
Description: Sklar's Micro-Cut Universal Style Biopsy Punch Forceps are an OB/GYN instrument used in colposcopy procedures to obtain cervical tissue samples for biopsy

Product Image-10100-114

Anti-ZNF781 Rabbit Polyclonal Antibody

Catalog Number: (10100-114)
Supplier: Prosci
Description: ZNF781 belongs to the krueppel C2H2-type zinc-finger protein family. It contains 4 C2H2-type zinc fingers. ZNF781 may be involved in transcriptional regulation. The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. The function of this peroxisomal membrane protein is unknown. However, it is speculated that it may function as a heterodimer for another peroxisomal ABC transporter and, therefore, may modify the adrenoleukodystrophy phenotype. It may also play a role in the process of peroxisome biogenesis. Alternative splicing results in at least two different transcript variants, one which is protein-coding and one which is probably not protein-coding.
Product Image-10194-070

Kevorkian Biopsy Punch, OR Grade, Sklar

Catalog Number: (10194-070)
Supplier: Sklar
Description: Kevorkian Biopsy Punch is used during colposcopy procedures to excise tissue from the endocervix for biopsy.
Product Image-10194-884

Keyes Skin Biopsy Set On Base, OR Grade, Sklar

Catalog Number: (10194-884)
Supplier: Sklar
Description: The Sklar Keyes Biopsy Punch is used to remove skin samples for biopsy
Product Image-10184-204

Kevorkian Micro-Cut Biopsy Punch Canula and Tip, OR Grade, Sklar

Catalog Number: (10184-204)
Supplier: Sklar
Description: Sklar's Kevorkian Micro-Cut Biopsy Punch Canula and Tip is part of an OB/GYN instrument
Image Unavailable-77663-724

Replacement Tips for Reusable Rapid Biopsy Punch

Supplier: WORLD PRECISION INSTRUMENTS LLC
Description: Stainless steel replacement tips for use with reusable rapid biopsy punch.

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Image Unavailable-10250-738

Anti-ABCA7 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (10250-738)
Supplier: Bioss
Description: ATP-binding cassette (ABC) transporters are an evolutionarily conserved family of widely-expressed proteins that use ATP hydrolysis to catalyze the transport of various molecules across extracellular and intracellular membranes. Eukaryotic ABC transporters are largely responsible for trafficking hydrophobic compounds either within the cell as part of a metabolic process, outside the cell for transport to other organs, or for secretion from the body. The cholesterol-responsive transporter, ABCA7, maps to human chromosome 19 and mouse chromosome 10 and has been reported as a candidate regulator of ceramide transport in epidermal lipid reorganization. High expression levels of ABCA7 have been reported in myelolymphatic tissues, reticuloendothelial cells, peripheral leukocytes, thymus, spleen and bone marrow. This expression pattern of the two alternatively-spliced isoforms also indicates an involvement in lipid homeostasis in cells of the immune system, though the complete role of ABCA7 is not yet known. Full-length type I ABCA7 has shown plasma membrane localization, while the type II splicing variant has shown expression predominantly in the endoplasmic reticulum.
Image Unavailable-10250-716

Anti-ABCA7 Rabbit Polyclonal Antibody

Catalog Number: (10250-716)
Supplier: Bioss
Description: ATP-binding cassette (ABC) transporters are an evolutionarily conserved family of widely-expressed proteins that use ATP hydrolysis to catalyze the transport of various molecules across extracellular and intracellular membranes. Eukaryotic ABC transporters are largely responsible for trafficking hydrophobic compounds either within the cell as part of a metabolic process, outside the cell for transport to other organs, or for secretion from the body. The cholesterol-responsive transporter, ABCA7, maps to human chromosome 19 and mouse chromosome 10 and has been reported as a candidate regulator of ceramide transport in epidermal lipid reorganization. High expression levels of ABCA7 have been reported in myelolymphatic tissues, reticuloendothelial cells, peripheral leukocytes, thymus, spleen and bone marrow. This expression pattern of the two alternatively-spliced isoforms also indicates an involvement in lipid homeostasis in cells of the immune system, though the complete role of ABCA7 is not yet known. Full-length type I ABCA7 has shown plasma membrane localization, while the type II splicing variant has shown expression predominantly in the endoplasmic reticulum.
Product Image-10193-958

Tischler Oval Biopsy Punch, OR Grade, Sklar

Catalog Number: (10193-958)
Supplier: Sklar
Description: Sklar's® Tischler Elliptical / Oval Biopsy Punch is a non-ratcheted, double spring OB/GYN instrument used in colposcopy procedures to obtain cervical tissue samples for biopsy.
Product Image-10194-886

Sharpening Stone for Keyes Biopsy Punches, OR Grade, Sklar

Catalog Number: (10194-886)
Supplier: Sklar
Description: Sklar's Sharpening Stone for Keyes Biopsy Punches is a stainless steel and diamond pen-like tool used to sharpen the tips of Keyes Biopsy Punch.
Product Image-10193-846

Tru-Punch™ Sterile Disposable Biopsy Punches, Sklar

Supplier: Sklar
Description: Single-use dermal biopsy punches.

Product Image-10194-148

Tischler-Kevorkian Micro-Cut Biopsy Punch, OR Grade, Sklar

Catalog Number: (10194-148)
Supplier: Sklar
Description: Tischler-Kevorkian Micro-Cut Biopsy Punch is an OB/GYN instrument used in colposcopy procedures to obtain cervical tissue samples for biopsy.
Product Image-10194-170

Micro-Cut Universal Style Biopsy Punch Kevorkian, OR Grade, Sklar

Catalog Number: (10194-170)
Supplier: Sklar
Description: Sklar® Micro-Cut Universal Style Biopsy Punch is a reusable, stainless steel, premium OR grade punch.
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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