Print…

You Searched For: Apoptosis+activator+2


65,408  results were found

Refine Results Sort by
SearchResultCount:"65408"

Sort Results

List View Easy View

Rate These Search Results

Product Image-77753-430

Human/Mouse/Rat Recombinant Activin-A (from E. coli)

Supplier: VWR International
Description: Activin A is a member of the transforming growth factor beta (TGF-β) family of proteins and functions to stimulate follicle-stimulating hormone (FSH) secretion.  Activins are produced in many tissue types including the skin, gonads, lungs, and pituitary gland. Activins interact with receptor type I and type II serine/threonine protein kinases, to activate SMAD signaling and regulate diverse cellular functions, such as cell proliferation, differentiation, wound healing, apoptosis, and metabolism.  Activin A is a homodimer comprised of two activin βA chains. Cleavage of the N-terminal propeptide renders the Activin protein biologically active. Human Activin A shares 100% amino acid sequence identity with mouse, rat, porcine, bovine, and feline Activin A proteins.

New Product

Product Image-77753-362

Human Recombinant RH IL-4 (from E. coli)

Supplier: VWR International
Description: IL-4 is an immunomodulatory cytokine that stimulates B cell proliferation and activates eosinophils, basophils, and mast cells. Induces vascular cell adhesion molecule (VCAM)-1 expression on endothelial cells and involved in collagen production by fibroblasts. Plays a key role in promotion of Th2 differentiation from naïve helper T cells. Defines the Th2 phenotype of lymphocytes. Regulates cell proliferation, apoptosis, and expression of numerous genes in various cell types. The biological activity of CTGrade GMP interleukins and growth factors is standardized, where applicable, to WHO International standards, providing cell and gene therapy developers consistent, lot-to-lot biological activity and performance.

New Product

Product Image-77750-446

Human Recombinant FGF-21 (from E. coli)

Supplier: VWR International
Description: Fibroblast growth factor 21 (FGF-21) is an endocrine hormone that regulates energy homeostasis and exerts cardioprotective functions during heart injury. FGF-21 is expressed in the liver, pancreas, heart, and adipose tissues. FGF-21 signaling is activated through the FGFR1c receptor and β-Klotho co-receptor. FGF-21 is an important regulator of glucose uptake and reduces cell apoptosis under stress conditions.

New Product

Product Image-77753-438

Human/Mouse/Rat Recombinant Activin-A (from E. coli)

Supplier: VWR International
Description: Activin A is a member of the transforming growth factor beta (TGF-β) family of proteins and functions to stimulate follicle-stimulating hormone (FSH) secretion.  Activins are produced in many tissue types including the skin, gonads, lungs, and pituitary gland. Activins interact with receptor type I and type II serine/threonine protein kinases, to activate SMAD signaling and regulate diverse cellular functions, such as cell proliferation, differentiation, wound healing, apoptosis, and metabolism.  Activin A is a homodimer comprised of two activin βA chains. Cleavage of the N-terminal propeptide renders the Activin protein biologically active. Human Activin A shares 100% amino acid sequence identity with mouse, rat, porcine, bovine, and feline Activin A proteins.

New Product

Image Unavailable-89155-990

Apoptosis inducer set, Enzo Life Sciences

Catalog Number: (89155-990)
Supplier: Enzo Life Sciences
Description: The set contains 5 ready-to-use reagents that induce apoptosis through different mechanisms. Actinomycin D, an antineoplastic antibiotic, inhibits RNA synthesis. Camptothecin, an inhibitor of nuclear topoisomerase, induces apoptosis in many types of cells. Cycloheximide, an active antibiotic against many yeast and fungi, inhibits protein synthesis. Dexamethasone, an active and highly stable glucocorticoid, probably induces apoptosis by binding and activating the intracellular glucocorticoid receptor. Etoposide, a derivative of podophyllotoxin, inhibits topoisomerase activity.
Image Unavailable-82603-578

CD437 ≥98% (by HPLC), Calbiochem®, Sigma-Aldrich®

Catalog Number: (82603-578)
Supplier: MilliporeSigma
Description: The Apoptosis Activator VI, CD437/AHPN, also referenced under CAS 125316-60-1, modulates Apoptosis. This small molecule/inhibitor is primarily used for Cancer applications.

SDS Certificates


Product Image-76714-600

Human Apoptosis Protease Activating Factor-1(APAF-1) ELISA Kit

Catalog Number: (76714-600)
Supplier: AFG Bioscience
Description: Human Apoptosis Protease Activating Factor-1(APAF-1) ELISA Kit
Image Unavailable-80603-046

Ns3694, Calbiochem®

Catalog Number: (80603-046)
Supplier: MilliporeSigma
Description: The Apoptosis Inhibitor II, NS3694, controls the biological activity of Apoptosis

SDS Certificates


Product Image-76482-082

FAM-LETD-FMK

Catalog Number: (76482-082)
Supplier: AAT BIOQUEST INC
Description: Activation of caspases plays a central role in apoptosis.

Small Business Enterprise Minority or Woman-Owned Business Enterprise


Product Image-89415-596

Anti-PHAP Rabbit Polyclonal Antibody

Catalog Number: (89415-596)
Supplier: Prosci
Description: PHAP Antibody: Apoptosis is related to many diseases and development. Caspase-9 plays a central role in cell death induced by a variety of apoptosis activators. Cytochrome c, after released from mitochondria, binds to Apaf-1, which forms an apoptosome that in turn binds to and activate procaspase-9. Activated caspase-9 cleaves and activates the effector caspases (caspase-3, -6 and -7), which are responsible for the proteolytic cleavage of many key proteins in apoptosis. The tumor suppressor putative HLA-DR-associated proteins (PHAPs) were recently identified as important regulators of mitochondrion apoptosis. PHAP appears to facilitate apoptosome-medicated caspase-9 activation and to stimulate the mitochondrial apoptotic pathway. PHAP was also shown to oppose both Ras- and Myc-medicated cell transformation.
Product Image-89415-592

Anti-PHAP Rabbit Polyclonal Antibody

Catalog Number: (89415-592)
Supplier: Prosci
Description: PHAP Antibody: Apoptosis is related to many diseases and development. Caspase-9 plays a central role in cell death induced by a variety of apoptosis activators. Cytochrome c, after released from mitochondria, binds to Apaf-1, which forms an apoptosome that in turn binds to and activate procaspase-9. Activated caspase-9 cleaves and activates the effector caspases (caspase-3, -6 and -7), which are responsible for the proteolytic cleavage of many key proteins in apoptosis. The tumor suppressor putative HLA-DR-associated proteins (PHAPs) were recently identified as important regulators of mitochondrion apoptosis. PHAP appears to facilitate apoptosome-medicated caspase-9 activation and to stimulate the mitochondrial apoptotic pathway. PHAP was also shown to oppose both Ras- and Myc-medicated cell transformation.
Product Image-10230-292

Anti-APAF1 Rabbit Polyclonal Antibody

Catalog Number: (10230-292)
Supplier: Bioss
Description: Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. Isoform 6 is less effective in inducing apoptosis.
Product Image-89415-590

Anti-PHAP3 Rabbit Polyclonal Antibody

Catalog Number: (89415-590)
Supplier: Prosci
Description: PHAP III Antibody: Apoptosis is related to many diseases and development. Caspase-9 plays a central role in cell death induced by a variety of apoptosis activators. Cytochrome c, after released from mitochondria, binds to Apaf-1, which forms an apoptosome that in turn binds to and activate procaspase-9. Activated caspase-9 cleaves and activates the effector caspases (caspase-3, -6 and -7), which are responsible for the proteolytic cleavage of many key proteins in apoptosis. The tumor suppressor putative HLA-DR-associated proteins (PHAPs) were recently identified as important regulators of mitochondrion apoptosis. PHAP appears to facilitate apoptosome-medicated caspase-9 activation and to stimulate the mitochondrial apoptotic pathway. PHAP was also shown to oppose both Ras- and Myc-medicated cell transformation.
Product Image-89415-588

Anti-PHAP1 Rabbit Polyclonal Antibody

Catalog Number: (89415-588)
Supplier: Prosci
Description: PHAP I Antibody: Apoptosis is related to many diseases and development. Caspase-9 plays a central role in cell death induced by a variety of apoptosis activators. Cytochrome c, after released from mitochondria, binds to Apaf-1, which forms an apoptosome that in turn binds to and activate procaspase-9. Activated caspase-9 cleaves and activates the effector caspases (caspase-3, -6 and -7), which are responsible for the proteolytic cleavage of many key proteins in apoptosis. The tumor suppressor putative HLA-DR-associated proteins (PHAPs) were recently identified as important regulators of mitochondrion apoptosis. PHAP appears to facilitate apoptosome-medicated caspase-9 activation and to stimulate the mitochondrial apoptotic pathway. PHAP was also shown to oppose both Ras- and Myc-medicated cell transformation.
Image Unavailable-AAJ63827-06

Harmol hydrochloride dihydrate 98%

Supplier: Thermo Scientific Chemicals
Description: Induces apoptosis by Caspase-8 activation

SDS Certificates

Image Unavailable-10230-080

Anti-APAF1 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalog Number: (10230-080)
Supplier: Bioss
Description: Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. Isoform 6 is less effective in inducing apoptosis.
Inquire for Price
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organization. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at 1-800-932-5000.
17 - 32 of 65,408
no targeter for Bottom