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Product Image-77589-830

Cell Culture Dishes, quadriPERM®

Catalog Number: (77589-830)
Supplier: SARSTEDT INC
Description: To keep cells happy, the selection of a suitable cultivation surface is essential. SARSTEDT offers a wide range of cell culture labware and accessories for many applications.

New Product


Product Image-PAV1731

PI3K (p110alpha[E545K]/p85alpha)

Catalog Number: (PAV1731)
Supplier: Promega Corporation
Description: The PI3K lipid kinase enzymes are used with ADP-Glo KInase Assay System and Lipid Kinase Substrates in a homogeneous, add-mix-read lipid kinase assay.
Product Image-76237-082

HyClone™ HyCell CHO Cell Culture Media, HyClone products (Cytiva)

Supplier: Cytiva
Description: HyCell™ CHO media has been developed for CHO cell culture for bioprocess applications.

SDS

Image Unavailable-10785-666

Accessories for PrimaCell™, Rat Colorectal Smooth Muscle Cell Culture Kit, CHI Scientific

Supplier: CHI Scientific

Image Unavailable-10783-422

Accessories for PrimaCell™, Mouse Normal Cerebellar Granule Cell Culture Kit, CHI Scientific

Supplier: CHI Scientific

Image Unavailable-10784-202

Accessories for PrimaCell™, Rat Adipose Cell Culture Kit, CHI Scientific

Supplier: CHI Scientific

Product Image-16005-088

Blood Bank Saline Solutions, Azer Scientific

Supplier: Azer Scientific Inc.
Description: Blood bank saline is pH-controlled for a pH between 6.5 and 7.0

Certificates Minority or Woman-Owned Business Enterprise Product available on GSA Advantage®

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Accessories for PrimaCell™, Human Bladder Tumor Cell Culture Kit, CHI Scientific

Supplier: CHI Scientific

Image Unavailable-10785-842

Accessories for PrimaCell™, Human Colorectal Tumor Cell Culture Kit, CHI Scientific

Supplier: CHI Scientific

Product Image-76462-606

HyClone Cell Boost™ 7b Supplement, HyClone products (Cytiva)

Supplier: Cytiva
Description: Supplements cell culture with concentrated amino acids. Manufactured to meet cGMP manufacturing standards and QC specifications.

SDS

Product Image-15705-068

Corning® Primaria™ Cell Culture Flasks, Corning

Supplier: Corning
Description: PS, tissue culture-treated, sterile, non-pyrogenic

Certificates

Product Image-76474-604

Accessories for Corning® Closed System Cell Cubes, Corning

Supplier: Corning
Description: Corning®, Cell Culture Plate, CellCube adaptor, F MPC, 1/4

Environmentally Preferable

Image Unavailable-76109-422

Anti-Histone H2A.X Ubiquityl Lys119 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (76109-422)
Supplier: Bioss
Description: Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Required for checkpoint-mediated arrest of cell cycle progression in response to low doses of ionizing radiation and for efficient repair of DNA double strand breaks (DSBs) specifically when modified by C-terminal phosphorylation.
Product Image-76452-614

HumaCoat Human Skin Collagen Type I, 1 mg/ml Solution, Humabiologics

Catalog Number: (76452-614)
Supplier: HUMABIOLOGICS, INC
Description: Clinically relevant native human skin collagen for cell culture coating applications.
Image Unavailable-102868-752

Mouse Recombinant R-Spondin 1 (from CHO cells)

Catalog Number: (102868-752)
Supplier: R&D Systems
Description: The Recombinant Mouse R-Spondin 1 (CHO-expressed) Protein from R&D Systems is derived from CHO. The Recombinant Mouse R-Spondin 1 (CHO-expressed) Protein has been validated for the following applications: Bioactivity.
Image Unavailable-10393-104

Anti-HLA-DPB1 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (10393-104)
Supplier: Bioss
Description: Binds peptides derived from antigens that access the endocytic route of antigen presenting cells (APC) and presents them on the cell surface for recognition by the CD4 T-cells. The peptide binding cleft accommodates peptides of 10-30 residues. The peptides presented by MHC class II molecules are generated mostly by degradation of proteins that access the endocytic route, where they are processed by lysosomal proteases and other hydrolases. Exogenous antigens that have been endocytosed by the APC are thus readily available for presentation via MHC II molecules, and for this reason this antigen presentation pathway is usually referred to as exogenous. As membrane proteins on their way to degradation in lysosomes as part of their normal turn-over are also contained in the endosomal/lysosomal compartments, exogenous antigens must compete with those derived from endogenous components. Autophagy is also a source of endogenous peptides, autophagosomes constitutively fuse with MHC class II loading compartments. In addition to APCs, other cells of the gastrointestinal tract, such as epithelial cells, express MHC class II molecules and CD74 and act as APCs, which is an unusual trait of the GI tract. To produce a MHC class II molecule that presents an antigen, three MHC class II molecules (heterodimers of an alpha and a beta chain) associate with a CD74 trimer in the ER to form a heterononamer. Soon after the entry of this complex into the endosomal/lysosomal system where antigen processing occurs, CD74 undergoes a sequential degradation by various proteases, including CTSS and CTSL, leaving a small fragment termed CLIP (class-II-associated invariant chain peptide). The removal of CLIP is facilitated by HLA-DM via direct binding to the alpha-beta-CLIP complex so that CLIP is released. HLA-DM stabilizes MHC class II molecules until primary high affinity antigenic peptides are bound. The MHC II molecule bound to a peptide is then transported to the cell membrane surface.
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at 1-800-932-5000.
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