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Catalog Number: (77753-602)
Supplier: VWR International
Description: Cytokines for expansion and cell culture of mouse hematopoietic stem cells. Hematopoietic stem cells are self renewing pluripotent cells often characterized by the expression of CD34. Studies have shown that decreased expression of CD34 tends to correlate with decreased self renewal properties and pluripotent potential. Culturing CD34+ cells in a cytokine mixture of TPO, SCF, and FLT-3 Ligand for short time periods allows CD34+ cells to proliferate without decreasing CD34 expression, thus retaining their stem cell properties. The combination of these cytokines allows for the ex vivo expansion of the most immature hematopoietic stem cells in cord blood or bone marrow preparations, but can be supplemented with other cytokines to promote specific lineages.

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Supplier: VWR
Description: 1X Solution Composition:137 mM NaCl,2.7 mM KCl,9.8 mM Phosphate buffer
May be sterilized by filtration.
Does not contain magnesium or calcium.
pH at 25°C (1X PBS): 7.3 – 7.5
Conductivity at 25°C (1X PBS): 13,500-17,000 umhos
Catalog Number: (102869-570)
Supplier: R&D Systems
Description: R-Spondin 3 Affinity Purified Polyclonal Antibody, Sheep IgG, Species Reactivity: Human, Immunogen: Chinese hamster ovary cell line CHO-derived recombinant human R-Spondin 3. Gln22-His272 Accession Number Q9BXY4, 100 UG


Supplier: VWR International
Description: <p>Leukemia inhibitory factor (LIF) is a member of the interleukin 6 (IL-6) family that is made by a variety of adult and embryonic tissues. LIF signals through the glycoprotein 130 (gp130)/LIF receptor (LIFR) heterodimer to activate STAT3 and MAPK signaling. LIF functions during hematopoietic differentiation, neuronal cell differentiation, kidney development, and inflammatory processes. Mouse LIF promotes mouse embryonic stem (ES) cell self-renewal and pluripotency in long-term cell culture systems, similar to the functional activity of FGF-basic in human ES cell culture systems.</p>

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Catalog Number: (102869-984)
Supplier: R&D Systems
Description: Semaphorin 4G Affinity Purified Polyclonal Antibody, Sheep IgG, Species Reactivity: Mouse, Immunogen: Mouse myeloma cell line NS0-derived recombinant mouse Semaphorin 4G. Val18-Met673 Accession Number Q9WUH7, 100 UG


Catalog Number: (102869-970)
Supplier: R&D Systems
Description: PILR-alpha Affinity Purified Polyclonal Antibody, Sheep IgG, Species Reactivity: Human, Immunogen: Mouse myeloma cell line NS0-derived recombinant human PILR-alpha . Gln20-Thr196 Accession Number Q9UKJ1, 100 UG


Catalog Number: (10100-996)
Supplier: Prosci
Description: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter.Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.


Catalog Number: (77753-606)
Supplier: VWR International
Description: Cytokines for expansion and cell culture of mouse hematopoietic stem cells to progenitor cells. Hematopoietic stem cells are self renewing pluripotent cells often characterized by the expression of CD34. Studies have shown that decreased expression of CD34 tends to correlate with the decreased self renewal properties and pluripotent potential. Culturing CD34+ cells in a cytokine mixture of SCF, FLT-3 Ligand, IL-6 and IL-3 for short time periods allows rapid expansion of immature and more mature hematopoietic progenitor cells in cord blood or bone marrow preparations. If the goal is to only expand the most immature progenitor and stem cells, it is recommended that a combination of TPO, SCF and FLT-3 Ligand are used (Catalog: PB-500-04). Either cytokine combination can also be supplemented with other cytokines to promote specific lineages.

New Product


Catalog Number: (77753-600)
Supplier: VWR International
Description: <p>Cytokines for expansion and cell culture of human hematopoietic stem cells. Hematopoietic stem cells are self renewing pluripotent cells often characterized by the expression of CD34. Studies have shown that decreased expression of CD34 tends to correlate with decreased self renewal properties and pluripotent potential.</p>

New Product


Catalog Number: (102870-130)
Supplier: R&D Systems
Description: CLEC9a Affinity Purified Polyclonal Antibody, Sheep IgG, Species Reactivity: Mouse, Immunogen: Chinese hamster ovary cell line CHO-derived recombinant mouse CLEC9a. Lys57-Ile264 Accession Number EDK99924, 100 UG


Catalog Number: (102869-632)
Supplier: R&D Systems
Description: CD39L3/ENTPD3 Affinity Purified Polyclonal Antibody, Sheep IgG, Species Reactivity: Human, Immunogen: Mouse myeloma cell line NS0-derived recombinant human CD39L3/ENTPD3. Gln44-Pro485 Accession Number O75355, 100 UG


Catalog Number: (102869-534)
Supplier: R&D Systems
Description: Granzyme A Affinity Purified Polyclonal Antibody, Goat IgG, Species Reactivity: Human, Immunogen: Mouse myeloma cell line NS0-derived recombinant human Granzyme A. Cys26-Val262 Accession Number P12544, 100 UG


Catalog Number: (102878-678)
Supplier: R&D Systems
Description: Human Cathepsin H Affinity Purified Polyclonal Antibody, Sheep IgG, Immunogen:Chinese hamster ovary cell line CHO-derived recombinant human Cathepsin H. Ala23-Val335 Accession Number CAA34734, Application: WB


Catalog Number: (102869-612)
Supplier: R&D Systems
Description: TAFA2/FAM19A2 Affinity Purified Polyclonal Antibody, Sheep IgG, Species Reactivity: Human, Immunogen: Mouse myeloma cell line NS0-derived recombinant human TAFA2/FAM19A2. Ala31-His131 Accession Number Q8N3H0, 100 UG


Catalog Number: (102869-968)
Supplier: R&D Systems
Description: CEACAM-1 Affinity Purified Polyclonal Antibody, Sheep IgG, Species Reactivity: Mouse, Immunogen: Mouse myeloma cell line NS0-derived recombinant mouse CEACAM-1/CD66a. Met1-Gly428 Accession Number P31809, 100 UG


Catalog Number: (102869-726)
Supplier: R&D Systems
Description: Siglec-E Affinity Purified Polyclonal Antibody, Goat IgG, Species Reactivity: Mouse, Immunogen: Mouse myeloma cell line NS0-derived recombinant mouse Siglec-E. Gln20-Phe355 Accession Number Q6PJ50, 100 UG


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at 1-800-932-5000.
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