You Searched For: Ac-Lys-AMC+(acetate+salt)


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Supplier: AVANTOR PERFORMANCE MATERIALS US
Description: AR—The standard Macron Fine Chemicals™ grade of analytical reagents; suitable for laboratory and general use.
Catalog Number: (89160-348)
Supplier: Enzo Life Sciences
Description: Fluor de Lys®-HDAC8 is a fluorogenic, diacetylated peptide substrate for HDAC8 (histone deacetylase-8). Based on residues 379-382 of p53 (Arg-His-Lys(Ac)-Lys(Ac)), a site of regulatory acetylation by the p300 and CBP acetyltransferases (lysines 381, 382), it was the best for HDAC8 from among a panel of substrates patterned on p53, histone H3 and histone H4 acetylation sites. Fluor de Lys®-HDAC8 is deacetylated by HDAC8 at a rate of more than 10-fold that of the acetylated lysine substrate, Fluor de Lys® (BML-KI104; substrates both at 100 µM). Although named because of HDAC8’s preference for it, it is also an excellent substrate for SIRT1 (BMl-SE239; 5x the rate of BML-KI104 at 25 µM, 0.5 mM NAD+), SIRT2 and HeLa Nuclear Extract (BML-KI140; 3x KI-104 rate, 25 µM). Must be used in conjunction with Fluor de Lys® Developer II (BML-KI176). Sufficient for 100-200 assays of human recombinant HDAC8 (BML-SE145; 1 U/well, 50-100 µM substrate).


Catalog Number: (103008-544)
Supplier: Anaspec Inc
Description: This peptide is histone H4 (1-21), acetylated at lysine 12. The N-terminus contains a C-terminus GG linker followed by a biotinylated lysine. The acetylation of histone H4 plays a crucial role in structural changes that amplifies the binding of transcription factors to their recognition sites within the nucleosomes. Provided at >95% peptide purity, this peptide was dissolved in distilled water at 1 mg/ml and re-lyophilized to powder form.
Sequence:Ac-SGRGKGGKGLG-K(Ac)-GGAKRHRKV-GGK(Biotin)
MW:2644.1 Da
% peak area by HPLC:95
Storage condition:-20° C


Catalog Number: (M-2295.0001BA)
Supplier: Bachem Americas
Description: Ac-ED(edans)KPILFFRLGK(dabcyl)E-amide, a sensitive fluorescent (FRET) peptide substrate for cathepsin D. This enzyme can degrade extracellular matrix components and may facilitate the spread of tumor cells. High levels of active cathepsin D were found within senile plaques in brains of Alzheimer's patients.


Catalog Number: (97061-890)
Supplier: VWR
Description: A pH indicator (Yellow to Blue; range 3.8 - 5.4).

Catalog Number: (103008-678)
Supplier: Anaspec Inc
Description: This is an amidated peptide derived from residues 361-393 of human p53 tumor suppressor protein with acetylation at Lys382. This peptide is biotin-labeled at its N-terminus with a 6-carbon LC linker. Activated p53 functions to induce cell cycle arrest and apoptosis in response to signals such as DNA damage. Acetylation of p53 reduces ubiquitination by MDM2 and increases p53 half-life in vivo.
Sequence:Biotin-LC-GSRAHSSHLKSKKGQSTSRHK-K(Ac)-LMFKTEGPDSD-NH2
MW:4034.7 Da
% peak area by HPLC:95
Storage condition:-20° C


Supplier: TCI America
Description: CAS Number: 1946-82-3
MDL Number: MFCD00008233
Molecular Formula: C8H16N2O3
Molecular Weight: 188.23
Purity/Analysis Method: >97.0% (T)
Form: Crystal
Melting point (°C): 254
Specific rotation [a]20/D: 4.0 deg (C=4, H2O)
Supplier: Bachem Americas
Description: 250mg CAS: 40968-46-5 C12H26N6O3 FW: 302.38

Supplier: VWR
Description: Magnesium sulphate heptahydrate ACS
Catalog Number: (H-6134.0001BA)
Supplier: Bachem Americas
Description: PAR peptides (TRAP peptides and thrombin receptor-like peptides) activate the proteinase-activated receptors PAR-1 to PAR-4.


Catalog Number: (100504-948)
Supplier: Electron Microscopy Sciences
Description: A technique producing an electron dense osmiophilic polymer when Lucifer yellow is injected into cells. Lucifer yellow also can be viewed in living cells as a dye marker and is more sensitive than any other dye.

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Catalog Number: (BDH9288-2.5KG)
Supplier: VWR International
Description: Colorless or white solid

Catalog Number: (103007-656)
Supplier: Anaspec Inc
Description: This is a H3 peptide acetylated at the lysine residue at the 14th position. This peptide has been shown to act as part of the active promoter state and the extent of its acetylation could be driven by cis regulatory elements such as CpG contents at promoters. It's expression has been shown to be decreased as malignancy of ovarian epithelial tumors increased, suggesting that this peptide could act as a prognostic marker although it does not show significant relation with the occurence or development of ovarian tumors.
Sequence:KSTGG-K(Ac)-APRKQ
MW:1199.4 Da
% peak area by HPLC:95
Storage condition:-20° C


Catalog Number: (103007-664)
Supplier: Anaspec Inc
Description: This peptide is Histone 4 acetylated at lysine 12. Based on genome-wide localization studies, this peptide has been found to occupy promoter region at the transcription start sites, especially being associated with particular promoters that may drive high levels of mRNA transcripts stored in mature spermatozoa. Such observations have led to assumptions that H4K12Ac may be one of the epigenetic marks for developmentally important genes.
Sequence:SGRGKGGKGLG-K(Ac)-GGAKRHRK
MW:2034.4 Da
% peak area by HPLC:95
Storage condition:-20° C


Catalog Number: (H-7252.0500BA)
Supplier: Bachem Americas
Description: Stable isotope-labeled human ghrelin useful for pharmacokinetic/pharmacodynamic studies.


Supplier: MORAVEK BIOCHEMICALS MS
Description: Acetic acid sodium salt, [1,2-14C] ≥96% (by HPLC)

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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