You Searched For: PD-161570

Catalog Number: (103885-888)

Supplier: Sino Biological

Description: A DNA sequence encoding the human CD274 (NP_054862.1) (Met1-Arg238) was expressed.

Supplier: Strem Chemicals Inc

Description: CAS #: 2035-66-7. Size: 1g.

Catalog Number: (75789-262)

Supplier: Prosci

Description: CD274, also known as B7-H1 or programmed death ligand 1 (PD-L1), is a 40 kD type I transmembrane protein and a member of the B7 family within the immunoglobulin receptor superfamily. Programmed death-1 ligand-1 (PD-L1, CD274, B7-H1) has been identified as the ligand for the immunoinhibitory receptor programmed death-1(PD1/PDCD1) and has been demonstrated to play a role in the regulation of immune responses and peripheral tolerance. By binding to PD1 on activated T-cells and B-cells, PD-L1 may inhibit ongoing T-cell responses by inducing apoptosis and arresting cell-cycle progression. Accordingly, it leads to growth of immunogenic tumor growth by increasing apoptosis of antigen specific T cells and may contribute to immune evasion by cancers. PD-L1 thus is regarded as promising therapeutic target for human autoimmune disease and malignant cancers.

Supplier: Abcam

Description: Alexa Fluor® 555 Rabbit monoclonal [CAL10] to PD-L1.

New Product

Catalog Number: (76949-244)

Supplier: ANTIBODIES.COM LLC

Description: Mouse monoclonal [PDL1/2746] antibody to PD-L1 (PE) for Flow Cytometry and IF with samples derived from Human and Mouse.

Catalog Number: (76966-280)

Supplier: ANTIBODIES.COM LLC

Description: Recombinant mouse monoclonal [rPDL1/4773] antibody to PD-L1 for WB and IHC-P with samples derived from Human.

Supplier: Strem Chemicals Inc

Description: CAS #: 7440-05-3. Size: 5g.

Catalog Number: (AA46685-03)

Supplier: Thermo Scientific Chemicals

Description: Palladium(II) trimethylacetate

SDS Certificates

Catalog Number: (ABCA_AB236119-1MG)

Supplier: Abcam

Description: Rabbit monoclonal [EP12357] to Prostaglandin D Synthase (Lipocalin)/PDS - BSA and Azide free.

New Product

Supplier: Abcam

Description: Rabbit recombinant multiclonal [RM1012] to PD-L1.

New Product

Supplier: Abcam

Description: Rabbit monoclonal [EPR23546-160] to PD-L1.

New Product

Catalog Number: (ABCA_AB278124-1X96)

Supplier: Abcam

Description: Human PD-L1 ELISA Kit, fluorescent is a single-wash 90-min Simplestep used to quantify Human PD-L1 with a sensitivity of 1.04 pg/ml. The assay uses a simple mix-wash-read protocol with just one incubation and one wash step. - Fluorescent Sandwich ELISA - 530/570/590 nm readout : works on any standard plate reader

New Product

Catalog Number: (75842-364)

Supplier: BIOGEMS INTERNATIONAL INC.

Description: The 10F.9G2 monoclonal antibody specifically reacts with mouse CD274, also known as B7-H1 or PD-L1, a 43 kDa glycoprotein of the B7 family of the immunoglobulin superfamily. CD274 is expressed on the B and T lymphocytes, natural killer cells, and dendritic cells. The receptor for the B7-H1 molecule is PD-1, which contains an Immunoreceptor Tyrosine-based Inhibitory Motif (ITIM), and is expressed on activated B and T cells. The interaction between CD274 and PD-1 seems to downregulate the T and B immune responses.

Catalog Number: (75842-362)

Supplier: BIOGEMS INTERNATIONAL INC.

Description: The 10F.9G2 monoclonal antibody specifically reacts with mouse CD274, also known as B7-H1 or PD-L1, a 43 kDa glycoprotein of the B7 family of the immunoglobulin superfamily. CD274 is expressed on the B and T lymphocytes, natural killer cells, and dendritic cells. The receptor for the B7-H1 molecule is PD-1, which contains an Immunoreceptor Tyrosine-based Inhibitory Motif (ITIM), and is expressed on activated B and T cells. The interaction between CD274 and PD-1 seems to downregulate the T and B immune responses.

Catalog Number: (102211-282)

Supplier: Novus Biologicals

Description: The PD-1 Antibody from Novus Biologicals is a rabbit polyclonal antibody to PD-1. This antibody reacts with human, mouse, rat. The PD-1 Antibody has been validated for the following applications: Western Blot, ELISA, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunofluorescence.

Catalog Number: (75791-812)

Supplier: Prosci

Description: CD274, also known as B7-H1 or programmed death ligand 1 (PD-L1), is a 40 kD type I transmembrane protein and a member of the B7 family within the immunoglobulin receptor superfamily. Programmed death-1 ligand-1 (PD-L1, CD274, B7-H1) has been identified as the ligand for the immunoinhibitory receptor programmed death-1(PD1/PDCD1) and has been demonstrated to play a role in the regulation of immune responses and peripheral tolerance. By binding to PD1 on activated T-cells and B-cells, PD-L1 may inhibit ongoing T-cell responses by inducing apoptosis and arresting cell-cycle progression. Accordingly, it leads to growth of immunogenic tumor growth by increasing apoptosis of antigen specific T cells and may contribute to immune evasion by cancers. PD-L1 thus is regarded as promising therapeutic target for human autoimmune disease and malignant cancers.