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6-Bromo-1H-[1,2,3]triazolo[4,5-b]pyridine ≥98.0% (by HPLC, titration analysis)

Description: CAS Number: 92276-38-5
Molecular Formula: C5H3BrN4
Molecular Weight: 199.01
Purity/Analysis Method: >98.0% (HPLC,T)
Form: Crystal
Melting point (°C): 206
Catalog Number: TCB3034-5G
Supplier: TCI America

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Product Image-101786-574

4,5-Dimethoxy-2-methylaniline

Description: MF=C9H13No2 MW=167.21 Cas=41864-45-3 MDL=MFCD00130067 5G
Catalog Number: 101786-574
Supplier: Matrix Scientific
Image Unavailable-76773-918

6-Bromo-1H-imidazo[4,5-b]pyridin-2(3H)-one 95%

Description: 6-Bromo-1H-imidazo[4,5-b]pyridin-2(3H)-one 95%
Catalog Number: 76773-918
Supplier: Ambeed
Image Unavailable-77392-530

AASTY 6-45

Description: AASTYs (Acrylic acid-co-styrenes) - like AASTY 6-45 - are highly alternating copolymers, well-suited for generating native lipid nanodiscs. They are a 2022 novel developed series for membrane protein solubilization & stabilization. AASTY 6-45 gets it's name from its molecular weight and Acrylic Acid : Styrene Ratio. These varying ratios of acrylic acid to styrene contribute to the hydrophilic properties of our AASTYs. In general lighter AASTYs, like 6-45 tend to be more aggressive, while heavier AASTYs, such as 11-45 show higher thermodynamic stability.

The exact composition of AASTY copolymers shows different extraction efficiency, depending on the lipid composition of the lipid bilayers being formulated into nanodiscs. As AASTY is made by controlled radical polymerization techniques, the dispersity of polymer molecular weight distribution is low, and the molecular weights are controlled. This means that excess AASTY copolymer can be removed by dialysis after nanodisc formation. Based on previous findings on SMA, it is the expectation that AASTY of different molecular weights will display different rates of nanodisc formation, extraction efficacy, and stability of resulting nanodiscs.

Every membrane protein solubilization needs to undergo a screening process before. The characteristic phospholipid environment surrounding the different membrane proteins in question performs differently well with each polymer. To support you in this process we offer a handy Screening Kit for AASTYs to test them all. Additionally, we recommend the two following publications if you would like to get further information: Smith et al. 2020 & Timcenko et al. 2022
Catalog Number: 77392-530
Supplier: CUBE BIOTECH
Image Unavailable-102841-990

(6-Bromo-3H-imidazo[4,5-b]pyridin-2-yl)methanol ≥97%

Description: (6-Bromo-3H-imidazo[4,5-b]pyridin-2-yl)methanol ≥97%
Catalog Number: 102841-990
Supplier: Matrix Scientific
Product Image-101788-412

4,5-Difluorobenzimidazole

Description: MF=C7H4F2N2 MW=154.12 Cas=236736-21-3 MDL=MFCD00153122 100Mg
Catalog Number: 101788-412
Supplier: Matrix Scientific
Image Unavailable-TCD2026-250G

4,5-Dicyanoimidazole ≥98.0% (by HPLC, total nitrogen)

Description: CAS Number: 1122-28-7
MDL Number: MFCD00005194
Molecular Formula: C5H2N4
Molecular Weight: 118.10
Purity/Analysis Method: >98.0% (HPLC,N)
Form: Crystal
Melting point (°C): 175
Catalog Number: TCD2026-250G
Supplier: TCI America

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Image Unavailable-102893-490

1-Bromo-4,5-difluoro-2-(4-nitrophenoxy)benzene ≥97%

Catalog Number: 102893-490
Supplier: Matrix Scientific

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Image Unavailable-77884-964

4,5-Difluoro-2-iodoaniline 95%, Ambeed.Inc

Description: 4,5-Difluoro-2-iodoaniline 95%, Ambeed.Inc
Catalog Number: 77884-964
Supplier: Ambeed

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Image Unavailable-77405-468

Dimethyl-2-bromo-1H-imidazole-4,5-dicarboxylate

Description: Dimethyl-2-bromo-1H-imidazole-4,5-dicarboxylate
Catalog Number: 77405-468
Supplier: APOLLO SCIENTIFIC
Image Unavailable-102519-142

4-Bromo-2-(tert-butyl)-6-iodooxazolo[4,5-c]pyridine-7-carbaldehyde

Description: MF=C11H10BRIN2O2 MW=409.03 MDL=MFCD20487000 250MG
Catalog Number: 102519-142
Supplier: Matrix Scientific
Image Unavailable-102519-146

4-Bromo-2-(tert-butyl)-7-(dimethoxymethyl)-6-iodooxazolo[4,5-c]pyridine

Description: MF=C13H16BRIN2O3 MW=455.10 MDL=MFCD20487008 250MG
Catalog Number: 102519-146
Supplier: Matrix Scientific
Image Unavailable-102897-930

3-(2-Bromo-4,5-difluorophenoxy)propanoic acid ≥97%

Catalog Number: 102897-930
Supplier: Matrix Scientific

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Image Unavailable-102519-144

4-Bromo-2-(tert-butyl)-7-chloro-6-iodooxazolo[4,5-c]pyridine

Description: MF=C10H9BRCLIN2O MW=415.46 MDL=MFCD20487007 250MG
Catalog Number: 102519-144
Supplier: Matrix Scientific
Image Unavailable-AAH32695-14

4,5-Dimethyl-o-phenylenediamine, (∼15% H₂O) 98%

Description: 5g CAS: 3171-45-7, MDL: MFCD00007729
Catalog Number: AAH32695-14
Supplier: Thermo Scientific Chemicals

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Product Image-101918-068

6-Bromo-1H-imidazo[4,5-b]pyridin-2(3H)-one

Description: Matrix Scientific Part Number: 059396-250MG , MDL Number: MFCD17171335
Catalog Number: 101918-068
Supplier: Matrix Scientific
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