Human Recombinant IL-15 (from E. coli)

Supplier: VWR International

Human Recombinant IL-15 (from E. coli)

Human Recombinant IL-15 (from E. coli)

77751-806 77751-808 77751-810 77751-812

77751-806EA 757.5 USD

77751-806 77751-808 77751-810 77751-812

Human Recombinant IL-15 (from E. coli)

Proteins and Peptides

Interleukin 15 (IL-15) is a widely expressed proinflammatory cytokine that is structurally and functionally related to interleukin 2 (IL-2). IL-15 signals through JAK kinases to activate STAT3, STAT5, and STAT6 transcription factors. IL-15 regulates the activation of T cells, neutrophils, and macrophages, and is a stimulatory cytokine promoting dendritic cell function. IL-15 expression is dysregulated in chronic inflammatory disorders, including rheumatoid arthritis, psoriasis, and pulmonary inflammatory diseases. Therefore, IL-15 may serve as an effective therapeutic target, due to the beneficial outcomes of IL-15 neutralization in models of psoriasis and diabetes. Human IL-15 shows activity on mouse cells.

High quality
Low endotoxin
Affordable

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For research use only.

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