Human Recombinant GDF-15-D Mutant (from E. coli)

Supplier: VWR International

VWR100-172-1MG VWR100-172-20UG VWR100-172-500UG VWR100-172-5UG VWR100-172-100UG
77750-714EA 5590.35 USD
77750-714 77750-716 77750-718 77750-720 77750-712
Human Recombinant GDF-15-D Mutant (from E. coli)
Proteins and Peptides

Growth differentiation factor 15 (GDF-15) is a member of the transforming growth factor beta (TGF-β) family and is made by the placenta and cardiovascular tissues. GDF-15 regulates inflammatory and apoptotic pathways during cellular stress and injury. GDF-15 is emerging as a biomarker of early heart disease, such that increased levels of circulating GDF-15 are associated with an increased risk of developing heart failure. The GDF-15 D variant has a Histidine to an Aspartate substitution at amino acid position 7.



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