Human Recombinant IL-15 (from E. coli)

Supplier: VWR International

77751-798 77751-800 77751-802 77751-804
77751-798EA 696.9 USD
77751-798 77751-800 77751-802 77751-804
Human Recombinant IL-15 (from E. coli)
Proteins and Peptides

Interleukin 15 (IL-15) is a widely expressed proinflammatory cytokine that is structurally and functionally related to interleukin 2 (IL-2). IL-15 signals through JAK kinases to activate STAT3, STAT5, and STAT6 transcription factors. IL-15 regulates the activation of T cells, neutrophils, and macrophages, and is a stimulatory cytokine promoting dendritic cell function. IL-15 expression is dysregulated in chronic inflammatory disorders, including rheumatoid arthritis, psoriasis, and pulmonary inflammatory diseases. Therefore, IL-15 may serve as an effective therapeutic target, due to the beneficial outcomes of IL-15 neutralization in models of psoriasis and diabetes. Human IL-15 shows activity on mouse cells.



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  • Low endotoxin
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