Human Recombinant IL-34 (from CHO cells)

Supplier: VWR International

VWR100-220-100UG VWR100-220-10UG VWR100-220-1MG VWR100-220-500UG

77751-164EA 1403.9 USD

77751-164 77751-166 77751-168 77751-170

Human Recombinant IL-34 (from CHO cells)

Proteins and Peptides

Interleukin 34 (IL-34) was originally identified in humans, by large scale screening of secreted proteins; orthologs have also been found in chimpanzee, murine, rat and chicken. Human IL-34 is synthesized as a 242 amino acid (aa) precursor that contains a 20 aa signal sequence and a 222 aa mature chain. IL-34 is secreted as a homodimer and contains one potential N-glycosylation site.

High quality
Low endotoxin
Affordable

IL-34 increases proliferation of immune cells known as monocytes; it elicits its activity by binding the colony stimulating factor 1 Receptor (CSF-1R). Expression of IL-34 is most abundant in the spleen and is expressed in many other tissues including the heart, brain, liver, kidney, thymus, intestine and lung. Human IL-34 contains a C-terminal 6×-polyhistidine (6×His) tag.

Precaución: For research use only.

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