N-(4-n-Pentylcinnamoyl)anthranilic acid ≥96%, Moligand™
Supplier: ALADDIN SCIENTIFIC CORPORATION
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Warning
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Synonyms:
N-(p-Amylcinnamoyl)anthranilic acid, 2-[3-(4-Pentylphenyl)prop-2-enoylamino]benzoicacid, 2-(3-(4-Pentylphenyl)acrylamido)benzoic acid
N-(p-Amylcinnamoyl) anthranilic Acid (ACA), a cell permeable inhibitor of PLA2, has been reported to inhibit α-ketoisocaproic acid and glyceraldehyde-induced insulin secretion, as well as glucose-induced insulin secretion. Additionally, by inhibiting PLA2, ACA consequentially suppresses glucose-induced arachidonic acid formation in cells. Furthermore, research has shown ACA to modulate the activity of different transient receptor potential channels. In particular, ACA's blocking ability of diacylglycerol-activated TRP channels is of special interest since it offers the opportunity to interfere with receptor-induced Ca2+-dependent signaling processes in vascular smooth muscle cells and platelets.
Formula:
C₂₁H₂₃NO₃ MW: 337.419 g/mol Storage Temperature: Freezer |
MDL Number:
MFCD00211365 CAS Number: 110683-10-8 |
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