A-803467 ≥98%, Moligand™
Supplier: ALADDIN SCIENTIFIC CORPORATION
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Warning
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Synonyms:
5-(4-Chlorophenyl)-N-(3,5-dimethoxyphenyl)furan-2-carboxamide
A-803467 inhibits spontaneous and evoked action potentials in sensory neurons. It exhibits antinociceptive effects.A-803467 decreases the firing in spinal dorsal horn neurons in vivo.The small molecule A-803467 is a potent and selective Nav1.8 sodium channel blocker. Nav1.8 is a tetrodotoxin-resistant (TTX-R) sodium channel that contributes to pain sensation by transmitting pain stimuli in peripheral sensory neurons; blockage of this channel by A-803467 reduces pain with varying effectiveness in a number of different models.A-803467 has been used to further understand the role of Nav1.8 in transmitting pain stimuli and also can be used as an analgesic
Formula:
C₁₉H₁₆ClNO₄ MW: 357.79 g/mol Storage Temperature: Freezer |
MDL Number:
MFCD10574689 CAS Number: 944261-79-4 |
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