Paraffin wax blended with synthetic polymers, Solidification point: 56-58°C, in pastille form, Histosec® embedding agent for histology, without DMSO, Sigma-Aldrich®

Supplier: MilliporeSigma


M-Clarity™ quality level = MQ400

1.15161.2504 1.15161.9025
EM1.15161.2504EA 408.06 USD
EM1.15161.2504 EM1.15161.9025
Paraffin wax blended with synthetic polymers, Solidification point: 56-58°C, in pastille form, Histosec® embedding agent for histology, without DMSO, Sigma-Aldrich®
Paraffin wax blended with synthetic polymers

Histosec® pastilles (without DMSO) is an embedding medium for histology of samples of human origin. It is a paraffin enriched with polymers, also available with the addition of DMSO (dimethyl sulfoxide). DMSO increases the rate of penetration of paraffin and provides additional preservation of the tissue structures. Its melting range is between 56 - 58 °C and, within this range any specimen can be processed without fear of damage irrespective of the method used.
In most clinical laboratories the paraffinization is performed with an automated embedding system and is performed directly after the histoprocessing.


  • The paraffins are ready-to-use and are used at a temperature of 60 °C.


The Histosec® pastilles (without DMSO) are well soluble with the Intermedia Xylene or xylene substitutes (such as Neo-Clear(R)).
The paraffin is an IVD registered product and CE certified, thus can be used for clinical diagnostic purposes.

Storage Temperature: Ambient
CAS Number: 8002-74-2
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Specification Test Results

Solidification point (rotating thermometer method) 56 - 58 °C
Effect of heating (at 60 °C/100 g) clear melt within max. 20 hours
Solubility in xylene (at 20 °C/0.1 g in 5 ml) clear solute within max. 20 hours
Cutting results (4 µm slices) conforms
Solubility of slices in xylene < 50 seconds

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