Calcimycin (A23187) free acid (from Streptomyces chartreusensis), Calbiochem®

Supplier: MilliporeSigma

Synonyms: Calcium Ionophore A23187, Calcium Ionophore III, Antibiotic A23187

100105-1MG 100105-5MG 100105-10MG 100105-50MG

80055-580EA 85.88 USD

80055-580 80055-584 80055-578 80055-582

Calcimycin (A23187) free acid (from Streptomyces chartreusensis), Calbiochem®

Calcimycin (A23187)

A mobile ion-carrier that forms stable complexes with divalent cations. Useful for increasing intracellular Ca2+ levels. Also acts as an uncoupler of oxidative phosphorylation and inhibitor of mitochondrial ATPase activity. An antibiotic with weak activity against gram-positive bacteria. Also induces apoptosis in mouse lymphoma cell line (S49); however, has been shown to block apoptosis in other systems, such as when interleukin-3 (IL-3) is withdrawn from IL-3-dependent cells.

Formula: C₂₉H₃₇N₃O₆
MW: 523.63 g/mol

MDL Number: MFCD00151202
CAS Number: 52665-69-7

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