Silylation Grade Solvents
Supplier: Thermo Scientific
Use specially manufactured and packaged Silylation Grade Solvents to meet the exacting needs of silylation and other sensitive derivatization reactions.
- Purified, dried, and packaged under nitrogen in convenient Hypo-Vial™ sample storage vials,
- Supplied with elastomer septa to enable immediate access to the sample without exposure to moisture and oxygen
Recommended use: Avoid water or alcohol, as TMS reagents react with active hydrogen. Avoid enolizable ketones. Use dimethylformamide for steroids and other large molecules. Use dimethylsulfoxide to prepare TMS derivatives of tertiary alcohols and some compounds with low solubility in other silylation solvents.
Use polar solvents (acetonitrile, dimethylformamide, dimethylsulfoxide, pyridine, tetrahyrdrofuran) to facilitate reactions; nonpolar organic solvents may be used but will not accelerate the rate of reaction. Pyridine is an excellent solvent and reaction medium for MS reactions and is an HCI acceptor in reactions involving organochlorosilanes.
Precaución: For research use only. Not for use in diagnostic procedures.
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