Silylation Grade Solvents

Supplier: Thermo Scientific

TS-20062 TS-20672 TS-27530
10066-268EA 125.39 USD
10066-268 10066-272 10066-292
Silylation Grade Solvents
Chromatography Sorbents GC Sorbents

Use specially manufactured and packaged Silylation Grade Solvents to meet the exacting needs of silylation and other sensitive derivatization reactions.


  • Purified, dried, and packaged under nitrogen in convenient Hypo-Vial™ sample storage vials,
  • Supplied with elastomer septa to enable immediate access to the sample without exposure to moisture and oxygen


Recommended use: Avoid water or alcohol, as TMS reagents react with active hydrogen. Avoid enolizable ketones. Use dimethylformamide for steroids and other large molecules. Use dimethylsulfoxide to prepare TMS derivatives of tertiary alcohols and some compounds with low solubility in other silylation solvents.


Use polar solvents (acetonitrile, dimethylformamide, dimethylsulfoxide, pyridine, tetrahyrdrofuran) to facilitate reactions; nonpolar organic solvents may be used but will not accelerate the rate of reaction. Pyridine is an excellent solvent and reaction medium for MS reactions and is an HCI acceptor in reactions involving organochlorosilanes.


Precaución: For research use only. Not for use in diagnostic procedures.

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