BSTFA Silylation Reagents

Supplier: Thermo Scientific

TS-38828 TS-38829 TS-38830
10066-308EA 219.01 USD
10066-308 10066-310 10066-312
BSTFA Silylation Reagents
Chromatography Sorbents GC Sorbents

Improve GC analysis with Thermo Scientific™ BSTFA Silylation Reagent. The highly volatile byproducts mono(trimethylsilyl)trifluoroacetamide (BSTFA) and trifluoroacetamide elute with the solvent front to ensure excellent chromatographic separations.


  • Increased volatility
  • Store at 2 to 8 °C
  • Standard concentration: 98 to 100%
  • Standard components: Trimethylsilyl 2,2,2-trifluoro-N-(trimethylsilyl)acetimidate


This silylation reagent reacts with a wide range of polar compounds and is particularly well suited for the GC analyses of some lower boiling TMS-amino acids and TMS Krebs cycle acids.


BSTFA is a powerful thrimethylsilyl donor, with donor strength that is comparable to its unfluorinated analog BSA [N,O-Bis(trimethylsilyl)acetamide]. BSTFA reacts to replace labile hydrogens on a wide range of polar compounds with a Si(CH₃)₃ group.


Increased volatility of reaction byproducts mono(trimethylsilyl)trifluoroacetamide and trifluoroacetamide over corresponding nonfluorinated compounds from BSA. Increased volatility makes it possible to derivatize smaller molecules with which the TMS derivatives elute with the byproducts from BSA.

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