Calbiochem® Proteasome inhibitor II

Supplier: MilliporeSigma

539162-1MG 539162-5MG
80053-878EA 129.45 USD
80053-878 80053-880
Calbiochem® Proteasome inhibitor II
Proteins and Peptides

A potent and cell-permeable proteasome inhibitor


Inhibits the chymotrypsin-like activity of the pituitary multicatalytic proteinase complex (MPC; Ki=460nM). Does not inhibit the peptidylglutamyl-peptide hydrolyzing activity of MPC even at concentrations of 200µM. Also blocks the decay of l[kappa]B-[alpha] and l[kappa]B-[beta] proteins in exponentially growing WEHI 231 cells.

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