Virus Recombinant SARS-COV-2 Trim Spike D614G Mutant 100 µg (from Mammalian Cells)

Supplier: ReVacc Scientific

Cartoon illustration of protein

Functional binding test by ELISA assay

Purity test by gel

Purity test by SEC

Cartoon illustration of protein

Functional binding test by ELISA assay

Purity test by gel

Purity test by SEC

J23V36-100UG J23V36-500UG

76515-424EA 758.86 USD

76515-424 76515-426

Virus Recombinant SARS-COV-2 Trim Spike D614G Mutant 100 µg (from Mammalian Cells)

Proteins and Peptides

A recombinant trimeric form of the spike glycoprotein (S protein) of SARS-Cov-2 (GenBank: MN908947) bearing a mutated S protein from D (Asp) to G (Gly) at site of 614 was produced by human embryonic kidney HEK293F cells, followed by purification.

Protein function: Bind to its receptor

This product contains ectodomain of S protein with S1/S2 cleavage site knocked-down, and also had a pair of mutations (N1067P and L1068P), a HRV3C cleavage site, T4 foldon trimerization domain, C-terminal 8 hexa-histidine tag and twin-strep tag. Twin-strep tag can be used for streptavidin labeling.

This product has been run on SDS-PAGE with reduced condition and Native blue gels as well as SEC, with results proving trimerization and glycosylation. The binding to two control mAbs and CR3022 was tested in ELISAs.

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