T4 UvsY Protein (from T4 Phage)

Supplier: INTACT GENOMICS, INC MS

3572 3575
103753-194EA 369.23 USD
103753-194 103753-196
T4 UvsY Protein (from T4 Phage)
Enzymes

Offers the largest collection of T4 Enzymes and proteins in the industry.


  • Extremely high purity
  • Variety of uses including RPA optimization
  • Quality control is performed following the production of each new lot of product to ensure that it meets the quality standards and specifications designated for the product
  • 10X UvsY reaction buffer


UvsY is the phage T4 recombination mediator protein, and structural and biophysical studies provide insights into its role in T4 homologous recombination. During T4 homologous recombination, the UvsX recombinase must compete with the prebound gp32 single-stranded binding protein for DNA-binding sites and T4 UvsY Protein stimulates this filament nucleation event. UvsY is a 15.8 kDa protein with properties that are consistent with its role as mediator; it stimulates the DNA-dependent ATPase activity of UvsX, lowers the critical concentration of UvsX that is required for activity, and promotes strand exchange. UvsY efficiently promotes the UvsX-catalyzed strand invasion reaction by recruiting to ssDNA–gp32 complexes, promotes the release of gp32, and favors the binding of UvsX.

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