7-Amino-4-methyl-3-coumarinylacetic acid (AMCA-H) ~90% (by HPLC), BioReagent fluorescent dye, Sigma-Aldrich®

Irritant Warning

Warning

Synonyms: AMCA, 2H-1-Benzopyran-3-acetic acid, 7-Amino-4-methylcoumarin-3-acetic acid, Aminomethyl coumarin acetic acid, 2-(7-Amino-4-methyl-2-oxo-2H-chromen-3-yl)acetic acid

08445-100MG 08445-500MG

220032-778EA 135.18 USD

220032-778 220032-779

7-Amino-4-methyl-3-coumarinylacetic acid (AMCA-H) ~90% (by HPLC), BioReagent fluorescent dye, Sigma-Aldrich®

7-Amino-4-methyl-3-coumarinylacetic acid (AMCA-H)

AMCA is a useful agent for labeling proteins. Demonstrates a characteristic absorption peak at 345 nm with a fluorescence emission at 440-460 nm (blue region); however, when conjugated with proteins the absorption peak shifts to 355 nm with a fluorescence emission at 440-460 nm. It has a high fluorescence yield with a sufficient Stokes shift (100 nm) and is relatively photostable. Relatively easy to activate and couple to the N-terminal amino group of a peptide resulting in an acid stable amide bond.

Fluorescence - λex 350 nm; λem 433 nm in methanol

Formula: C₁₂H₁₁NO₄
MW: 233.22 g/mol

MDL Number: MFCD00081051
CAS Number: 106562-32-7

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