RO8191 ≥98%

Supplier: Cayman Chemical Company
Danger

Synonyms: RO4948191, 2-[2,4-Bis(trifluoromethyl)imidazo[1,2-a]1,8-naphthyridin-8-yl]-1,3,4-oxadiazole, 8-(1,3,4-Oxadiazol-2-yl)-2,4-bis(trifluoromethyl)-imidazo[1,2-a][1,8]naphthyridine

20449-1 20449-5 20449-10 20449-25
76292-940EA 38.18 USD
76292-940 76292-942 76292-944 76292-946
RO8191 ≥98%
RO8191

  • An IFNAR2 agonist


An IFNAR2 agonist with antiviral activity (EC50 = 200 nM in an anti-HCV replicon assay); exhibits 1:1 binding to the IFNAR2 extracellular domain; induces expression of IFN-stimulated genes without induction of genes encoding inflammatory cytokines and chemokines in vitro and in vivo; reduces HCV titer in HCV-infected humanized liver mice following oral administration

Formula: C₁₄H₅F₆N₅O
MW: 373.21 g/mol
Storage Temperature: Freezer
MDL Number: MFCD03102493
CAS Number: 691868-88-9
UN: 2811
ADR: 6.1,I
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Specification Test Results

Formulation A crystalline solid
Purity ≥98%
Stability ≥ 2 years

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