2-(5,6-Dimethyl-9-oxoxanthen-4-yl)acetic acid (DMXAA) ≥98%
Supplier: Cayman Chemical Company
- A STING activator and tumor vascular disrupting agent
A tumor vascular disrupting agent, inducing apoptosis in tumor vascular endothelium resulting in necrosis at the tumor core; potently activates the STING/TBK1/IRF3 signaling pathway in mouse leukocytes, inducing type-I-IFN production; inhibits VEGFR1 and VEGFR2 (IC50 = 119 and 11 µM, respectively)
Specification Test Results
Formulation | A crystalline solid |
Purity | ≥98% |
Stability | ≥ 2 years |
Learn more

About VWR
Avantor is a vertically integrated, global supplier of discovery-to-delivery solutions for...