2-(5,6-Dimethyl-9-oxoxanthen-4-yl)acetic acid (DMXAA) ≥98%

Supplier: Cayman Chemical Company

Synonyms: Vadimezan, ASA-404, DMXAA, 2-(5,6-Dimethyl-9-oxo-9H-xanthen-4-yl)acetic acid, 2-(5,6-Dimethyl-9-oxoxanthen-4-yl)acetic acid

14617-1 14617-5 14617-10 14617-25
76292-910EA 38.18 USD
76292-910 76292-912 76292-914 76292-916
2-(5,6-Dimethyl-9-oxoxanthen-4-yl)acetic acid (DMXAA) ≥98%
2-(5,6-Dimethyl-9-oxoxanthen-4-yl)acetic acid (DMXAA)

  • A STING activator and tumor vascular disrupting agent


A tumor vascular disrupting agent, inducing apoptosis in tumor vascular endothelium resulting in necrosis at the tumor core; potently activates the STING/TBK1/IRF3 signaling pathway in mouse leukocytes, inducing type-I-IFN production; inhibits VEGFR1 and VEGFR2 (IC50 = 119 and 11 µM, respectively)

Formula: C₁₇H₁₄O₄
Storage Temperature: Freezer
MDL Number: MFCD00870555
CAS Number: 117570-53-3
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Specification Test Results

Formulation A crystalline solid
Purity ≥98%
Stability ≥ 2 years


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