2-(5,6-Dimethyl-9-oxoxanthen-4-yl)acetic acid (DMXAA) ≥98%
Supplier: Cayman Chemical Company
Synonyms:
Vadimezan, ASA-404, DMXAA, 2-(5,6-Dimethyl-9-oxo-9H-xanthen-4-yl)acetic acid, 2-(5,6-Dimethyl-9-oxoxanthen-4-yl)acetic acid
14617-1
14617-5
14617-10
14617-25
76292-910EA
38.18
USD
76292-910
76292-912
76292-914
76292-916
2-(5,6-Dimethyl-9-oxoxanthen-4-yl)acetic acid (DMXAA) ≥98%
2-(5,6-Dimethyl-9-oxoxanthen-4-yl)acetic acid (DMXAA)
- A STING activator and tumor vascular disrupting agent
A tumor vascular disrupting agent, inducing apoptosis in tumor vascular endothelium resulting in necrosis at the tumor core; potently activates the STING/TBK1/IRF3 signaling pathway in mouse leukocytes, inducing type-I-IFN production; inhibits VEGFR1 and VEGFR2 (IC50 = 119 and 11 µM, respectively)
Formula:
C₁₇H₁₄O₄ Storage Temperature: Freezer |
MDL Number:
MFCD00870555 CAS Number: 117570-53-3 |
|
Specification Test Results
Formulation | A crystalline solid |
Purity | ≥98% |
Stability | ≥ 2 years |
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