Hygromycin B ≥90% (by HPLC)
Supplier: Invivogen
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Synonyms:
(3aS,3'R,4S,4'S,5'R,6R,6'R,7S,7aS)-4-(((1R,2S,3R,5S,6R)-3-Amino-2,6-dihydroxy-5-(methylamino)cyclohexyl)oxy)-6'-((S)-1-amino-2-hydroxyethyl)-6-(hydroxymethyl)octahydro-3aH-spiro[[1,3]dioxolo[4,5-c]pyran-2,2'-pyran]-3',4',5',7-tetraol
Hygromycin B Gold™ is an ultrapure Hygromycin B. Hygromycin B is an aminoglycoside antibiotic produced by streptomyces hygroscopicus. It kills bacteria, fungi and higher eukaryotic cells by inhibiting protein synthesis. It has been reported to interfere with translocation and to cause mistranslation at the 70S ribosome.
Hygromycin B is used as a selective agent in molecular genetics experiments on a wide variety of eukaryotic and prokaryotic species.
Información de suministro: Hygromycin B gold is supplied as a sterile filtered yellow solution at 100 mg/ml in HEPES buffer.
Formula:
C₂₀H₃₇N₃O₁₃ MW: 527.5 g/mol Storage Temperature: Freezer |
MDL Number:
MFCD06795479 CAS Number: 31282-04-9 |
Specification Test Results
Purity (HPLC) | ≥90% |
Endotoxin Level | <0.5 EU/mg |
Cell Culture Tested | Potency Validated in Hygromycin‑Sensitive and Hygromycin-Resistant Mammalian Cell Lines |
Non‑Cytotoxicity of Trace Contaminants | Absence of Long‑Term Effects Confirmed in Hygromycin‑Resistant Cells |
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