Anti-KRT8 & KRT18 Mouse Monoclonal Antibody (CF543) [clone: B22.1 B23.1]

Supplier: Biotium

BNC431221-100 BNC431221-500
75920-688EA 205.77 USD
75920-688 75920-690
Anti-KRT8 & KRT18 Mouse Monoclonal Antibody (CF543) [clone: B22.1 B23.1]
Antibodies
Cytokeratin 8 (CK8) belongs to the type II (or B or basic) subfamily of high molecular weight cytokeratins and exists in combination with cytokeratin 18 (CK18). This MAb cocktail recognizes all simple epithelia including glandular epithelium, for example thyroid, female breast, gastrointestinal tract, respiratory tract, and urogenital tract including transitional epithelium. All adenocarcinomas and most squamous carcinomas are positive but keratinizing squamous carcinomas are usually negative. This antibody is useful in demonstrating the presence of Paget cells; there is very little keratin 18 in the normal epidermis so only Paget cells are stained.Immunohistochemical staining with this MAb is indistinguishable from that obtained with monoclonal antibody 5D3.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®543 is an orange fluorescent dye (Ex/Em 541/560 nm) designed for the 543 nm laser line. It yields the brightest conjugates among spectrally similar dyes.

Type: Primary
Antigen: KRT8 & KRT18
Clonality: Monoclonal
Clone: Clone B22.1 B23.1
Conjugation: CF543
Epitope:
Host: Mouse
Isotype: IgGs
Reactivity: Human
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