Anti-FBXO5 Mouse Monoclonal Antibody (Biotin) [clone: EMI1/1176]

Supplier: Biotium

BNCB1176-100 BNCB1176-500
75925-712EA 205.77 USD
75925-712 75925-714
Anti-FBXO5 Mouse Monoclonal Antibody (Biotin) [clone: EMI1/1176]
Antibodies
This antibody recognizes a 56 kDa protein, which is identified as Early Mitotic Inhibitor-1 (EMI1). It regulates mitosis by inhibiting the anaphase promoting complex/cyclosome (APC). Emi1 is a conserved F box protein containing a zinc-binding region essential for APC inhibition. The Emi1 protein functions to promote cyclin A accumulation and S phase entry in somatic cells by inhibiting the APC complex. At the G1-S transition, Emi1 is transcriptionally induced by the E2F transcription factor. Emi1 overexpression accelerates S-phase entry and can override a G1 block caused by overexpression ofMore Product Information
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SPECIFICATIONS

Antigen Symbol FBXO5
Antigen Name EMI1
Environmentally Preferable
Antibody Type Primary
Clonality Monoclonal
Conjugation Biotin
Clone EMI1/1176
Reactivity Human
Host Mouse
Gene ID Unigene ID: 520506
Isotype IgG2a kappa
Western Blot Yes
ImmunoChemistry Yes
ImmunoFluorescence Yes
Concentration 0.1 mg/mL
Storage Buffer PBS/0.1% BSA/0.05% azide

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