Anti-CD34 Mouse Monoclonal Antibody (Biotin) [clone: HPCA1/1171]

Supplier: Biotium

BNCB1171-100 BNCB1171-500

75894-258EA 205.77 USD

75894-258 75894-260

Anti-CD34 Mouse Monoclonal Antibody (Biotin) [clone: HPCA1/1171]

Antibodies

This antibody recognizes a carbohydrate epitope on a single chain, transmembrane, heavily glycosylated protein of 90-120 kDa, which is identified as CD34 (VI international workshop on human differentiation antigens). Its expression is a hallmark for identifying pluripotent hematopoietic stem or progenitor cells. Its expression is gradually lost as lineage committed progenitors differentiate. CD34 is a marker of choice for staining blasts in acute myeloid leukemia. In addition, it is expressed by soft tissue tumors, such as solitary fibrous tumor and gastrointestinal stromal tumor. CD34 expression is also found in vascular endothelium. Additionally, proliferating endothelial cells overexpress this molecule than the non-proliferating endothelial cells. Anti-CD34 labels > 85% of angiosarcoma and Kaposi's sarcoma, but shows low specificity.

Type: Primary
Antigen: CD34
Clonality: Monoclonal
Clone: Clone HPCA1/1171
Conjugation: Biotin
Epitope:
Host: Mouse
Isotype: IgG1 kappa
Reactivity: Human, Rat

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