Anti-B2M Mouse Monoclonal Antibody (Biotin) [clone: B2M/1118]

Supplier: Biotium

BNCB1118-100 BNCB1118-500

75882-022EA 205.77 USD

75882-022 75882-024

Anti-B2M Mouse Monoclonal Antibody (Biotin) [clone: B2M/1118]

Antibodies

Beta-2 microglobulin is a 12 kDa protein with a pI of 5.6. Serum beta-2 microglobulin levels are a reflection of cell turnover. Levels rise with fever, inflammation, and infection. Increased serum levels are also seen in B-cell malignancies and in renal failure and may indicate a worse prognosis for patients with early-stage Hodgkins lymphoma. In urine, increased levels are seen in proximal renal tubular disease as well as renal transplant rejection. Beta-2 microglobulin levels can rise either because its rate of synthesis has increased (e.g. in AIDS, malignant monoclonal plasma cell dyscrasia, solid tumours and autoimmune disease) or because of impaired renal filtration (e.g. due to renal insufficiency, graft rejection or nephrotoxicity induced by post-transplantation immunosuppressive therapy).

Type: Primary
Antigen: B2M
Clonality: Monoclonal
Clone: Clone B2M/1118
Conjugation: Biotin
Epitope:
Host: Mouse
Isotype: IgG1 kappa
Reactivity: Human, Non-human primates

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