Anti-CDC20 Mouse Monoclonal Antibody (CF405S) [clone: CDC20/1102]

Supplier: Biotium

BNC041102-100 BNC041102-500
75909-302EA 205.77 USD
75909-302 75909-304
Anti-CDC20 Mouse Monoclonal Antibody (CF405S) [clone: CDC20/1102]
Antibodies
Cyclins, regulatory subunits that associate with kinases, control many of the important steps in cell cycle progression. The Cdc2 protein kinase (p34Cdc2) exhibits protein kinase activity in vitro and exists in a complex with both cyclin B and a protein homologous to p13SUC1. Cdc2 kinase is the active subunit of the M phase promoting factor (MPF) and the M phase-specific Histone H1 kinase. The p34Cdc2/cyclin B complex is required for the G2 to M transition. An additional cell cycle-dependent protein kinase, termed p55cdc, exhibits a high degree of homology with the S. cerevisiae proteins Cdc20 and Cdc4. The p55cdc transcript is readily detectable in a variety of cultured cell lines in growth phase, but disappears when cell growth is chemically arrested.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®405S is a blue fluorescent dye (Ex/Em 404/431 nm) with superior brightness compared to other blue dyes; it is also compatible with super-resolution imaging by SIM. Note: Conjugates of blue fluorescent dyes are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Type: Primary
Antigen: CDC20
Clonality: Monoclonal
Clone: Clone CDC20/1102
Conjugation: CF405S
Epitope:
Host: Mouse
Isotype: IgG1, kappa
Reactivity: Human
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