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Anti-TRIM29 Mouse Monoclonal Antibody [clone: TRIM29/1042]

Supplier: Biotium

BNUB1042-100 BNUB1042-500

75977-770EA 240.92 USD

75977-770 75977-772

Anti-TRIM29 Mouse Monoclonal Antibody [clone: TRIM29/1042]

Antibodies

This antibody recognizes a 66 kDa protein, which is identified as Tripartite motif-containing protein 29 (TRIM29). It interacts with the intermediate filament protein vimentin, a substrate for the PKC family of protein kinases, and with hPKCI-1, an inhibitor of the PKCs. TRIM29 protein contains both zinc finger and leucine zipper motifs, suggesting that the it may form homodimers and possibly associate with DNA. High expression of TRIM29 has been reported in gastric cancer and pancreatic cancer, and correlates with enhanced tumor growth and lymph node metastasis. TRIM29 is also able to distinguish lung squamous cell carcinoma from lung adenocarcinoma with ~90% positive accuracy, when used in a panel with TTF-1, p63, CK5/6, and Napsin-A antibodies.

Type: Primary
Antigen: TRIM29
Clonality: Monoclonal
Clone: TRIM29/1042
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype: IgG2b, kappa
Reactivity: Human

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